Results 131 to 140 of about 65,436 (336)

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

open access: yesAdvanced Science, EarlyView.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai   +7 more
wiley   +1 more source

Effect of iron chelation on inflammatory joint disease. [PDF]

open access: bronze, 1987
Fiona Andrews   +3 more
openalex   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

open access: yesAdvanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu   +4 more
wiley   +1 more source

DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation

open access: yesAdvanced Science, EarlyView.
DR5 knockout exhibits a thinner colonic mucus layer, leading to mild dysbiosis, increased susceptibility to Citrobacter rodentium invasion, and exacerbated epithelial injury. Mechanistically, DR5 binds transcription factor TBP, which regulates the expression of gene Best2 via its promoter.
Ying Wang   +9 more
wiley   +1 more source

Research Progress on Iron Chelates of Foodborne Peptides

open access: yesShipin gongye ke-ji
Iron is an essential nutrient for maintaining red blood cell metabolism and assisting bone marrow hematopoiesis. Iron deficiency can cause various diseases, such as anemia, stunted growth, and premature birth in pregnant women.
Ying ZHOU   +7 more
doaj   +1 more source

Full Sequence Bleaching with Dimethyldioxirane [PDF]

open access: yes, 1995
Research work to date has shown dimethyldioxirane to be a very powerful, yet highly selective oxidant. Dimethyldioxirane bleaching may become more important in the future with legislative restrictions on chlorine based bleaching agents as it contains no ...
Krueger, Daniel
core   +1 more source

Revealing Robust Atomic Configurations of the Ligand‐Assisted Synthesized High‐Entropy PtIrFeCoNiCu Nano‐Intermetallic Catalysts During Oxygen Reductions in Fuel Cells

open access: yesAdvanced Science, EarlyView.
A facile ligand‐assisted strategy is developed to synthesize nanosized high‐entropy PtIr‐iHEA/C intermetallic catalyst (∼4.8 nm, 90% ordered). Structural analysis during oxygen reduction reveals its surface reconstructions, leading to a core–shell atomic configuration (PtIr‐iHEA@Pt) that originates the superior durability.
Yuting Jiang   +5 more
wiley   +1 more source

Monitoring iron chelation effect in hearts of thalassaemia patients with improved sensitivity using reduced transverse relaxation rate (RR2) [PDF]

open access: yes, 2010
Posters - Myocardial Viability: Human Models: No. 3660Accurate MRI characterization of myocardial iron is needed to improve the diagnosis and management of thalassaemia patients with transfusional iron overload. This study aimed to demonstrate that a new
Au, WY   +13 more
core  

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

open access: yesAdvanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao   +12 more
wiley   +1 more source

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