Biological activities and chemical composition of methanolic extracts of selected Autochthonous microalgae strains from the Red Sea [PDF]
, 2015 Four lipid-rich microalgal species from the Red Sea belonging to three different genera (Nannochloris, Picochlorum and Desmochloris), previously isolated as novel biodiesel feedstocks, were bioprospected for high-value, bioactive molecules.
Carolina Bruno De Sousa +14 more
core +4 more sources
From Iron Chelation to Overload as a Therapeutic Strategy to Induce Ferroptosis in Leukemic Cells
Frontiers in Oncology, 2020 Despite its crucial importance in numerous physiological processes, iron also causes oxidative stress and damage which can promote the growth and proliferation of leukemic cells.
E. Grignano +3 more
semanticscholar +1 more source
Overview of chelation recommendations for thalassaemia and sickle cell disease
Thalassemia Reports, 2014 The long term consequences of iron toxicity are mostly reversible with effective iron chelation therapy. Recommendations for use of chelation therapy in transfusion dependent thalassaemia (TDT), sickle cell disease (SCD) and non transfusion dependent ...
Banu Kaya
doaj +1 more source
Antioxidant and antihemolytic activities of methanol extract of Hyssopus angustifolius [PDF]
, 2012 This study was designed to evaluate antioxidant and antihemolytic activities of Hyssopus angustifolius flower, stem and leaf methanol extracts by employing various in vitro assays.
Alinezhad, H. +6 more
core +3 more sources
Iron Pathways and Iron Chelation Approaches in Viral, Microbial, and Fungal Infections
Pharmaceuticals, 2020 Iron is an essential element required to support the health of organisms. This element is critical for regulating the activities of cellular enzymes including those involved in cellular metabolism and DNA replication.
Ravneet Chhabra +5 more
semanticscholar +1 more source
Iron Chelation Therapy in Myelodysplastic Syndromes
Advances in Hematology, 2010 Myelodysplastic syndromes (MDS) are a heterogeneous disorder of the hematopoietic stem cells, frequently characterized by anemia and transfusion dependency. In low-risk patients, transfusion dependency can be long lasting, leading to iron overload.
Emanuela Messa +2 more
doaj +1 more source
Bistable equilibrium points of mercury body burden [PDF]
, 2007 In the last century mercury levels in the global environment have tripled as a result of increased pollution from industrial, occupational, medicinal and domestic uses \cite{BaMe03}. Glutathione is known to be the main agent responsible for the excretion
Boulos, Areen, Owhadi, Houman
core +2 more sources
Can iron chelation as an adjunct treatment of COVID-19 improve the clinical outcome?
European Journal of Clinical Pharmacology, 2020 A recent bioinformatic study showed that one of the important pathogenic effects of coronavirus disease 2019 (COVID-19) is through the direct damage of haemoglobin molecules by the novel coronavirus (SARS-CoV-2) [1].
Anis Abobaker
semanticscholar +1 more source
Challenges of Iron Chelation in Thalassemic Children
Thalassemia ReportsThalassemia treatment still relies on supportive care, mainly including blood transfusion and iron chelation therapy. Iron chelation is considered the main factor responsible for the marked improvement in survival rates of thalassemic patients ...
Alkistis Adramerina, Marina Economou
doaj +1 more source
Naringin is a promising natural compound for therapy of iron-overload disorders
Brazilian Journal of Pharmaceutical Sciences, 2022 Naringin has been shown to exhibit satisfying iron chelation capacity. Considering the side effects of routinely-used iron chelator (desferrioxamine, DFO), we decided to evaluate the iron chelation potency of naringin to discover whether or not it can be
Mehrdad Jahanshahi +3 more
doaj +1 more source