Results 71 to 80 of about 1,030,253 (321)
Ironing out the details: Untangling dietary iron and genetic background in diabetes [PDF]
, 2018 The search for genetic risk factors in type-II diabetes has been hindered by a failure to consider dietary variables. Dietary nutrients impact metabolic disease risk and severity and are essential to maintaining metabolic health.
Lawson, Heather A, Miranda, Mario A
core +2 more sources
Controversies on the Consequences of Iron Overload and Chelation in MDS
HemaSphere, 2020 Many patients with MDS are prone to develop systemic and tissue iron overload in part as a consequence of disease-immanent ineffective erythropoiesis. However, chronic red blood cell transfusions, which are part of the supportive care regimen to correct ...
F. Vinchi, S. Hell, U. Platzbecker
semanticscholar +1 more source
Iron Chelation and Multiple Sclerosis
ASN Neuro, 2014 Histochemical and MRI studies have demonstrated that MS (multiple sclerosis) patients have abnormal deposition of iron in both gray and white matter structures. Data is emerging indicating that this iron could partake in pathogenesis by various mechanisms, e.g., promoting the production of reactive oxygen species and enhancing the production of ...
Sharon G. Lynch +2 more
openaire +4 more sources
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
Advanced Functional Materials, EarlyView.This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson +12 more
wiley +1 more source
Journal of Rawalpindi Medical College, 2019 Background: To compare hydroxyurea plus iron chelation therapy with iron chelation therapy alone in controlling iron overload in children with beta thalassaemia major.
Tatheer Zahra +2 more
doaj
In vivo analysis of staphylococcus aureus-infected mice reveals differential temporal and spatial expression patterns of fhuD2 [PDF]
, 2017 Staphylococcus aureus is an opportunistic human pathogen and a major cause of invasive infections such as bacteremia, endocarditis, pneumonia and wound infections.
Bacconi, Marta +7 more
core +1 more source
Metal Nanoclusters for Cancer Imaging and Treatment
Advanced Functional Materials, EarlyView.This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu +5 more
wiley +1 more source
Cell Death Discovery, 2019 Iron overload, notably caused by hereditary hemochromatosis, is an excess storage of iron in various organs that causes tissue damage and may promote tumorigenesis.
N. Rainey +5 more
semanticscholar +1 more source
Cu2O/Cu Chiral Catalysts for Highly Selective Solar‐Assisted CO2‐to‐CO Electroreduction
Advanced Functional Materials, EarlyView.To address the poor target‐product selectivity of the eCO2RR, breakthrough approaches based on the chiral‐induced spin selectivity phenomenon enhance the Faradaic efficiency (FE) for target hydrocarbons, such as CO. To induce this spin polarization strategy in Cu2O/Cu catalysts, it is proposed using amine‐based intermediate organic molecules with ...
Hyungsoo Lee +13 more
wiley +1 more source
Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis [PDF]
, 2018 Background. The lead (Pb) exposure crisis in Flint, Michigan has passed from well-publicized event to a footnote, while its biological and social impact will linger for lifetimes.
Bayon, Baindu L. +3 more
core +1 more source