Results 81 to 90 of about 1,030,253 (321)

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia.

open access: yesCochrane Database of Systematic Reviews, 2018
BACKGROUND Regularly transfused people with sickle cell disease (SCD) and people with thalassaemia (who are transfusion-dependent or non-transfusion-dependent) are at risk of iron overload.
Patricia Fortin   +6 more
semanticscholar   +1 more source

Mechanisms of Anode Interfacial Phenomena and Multi‐perspective Optimization in Aqueous Alkaline Zinc‐Air Batteries

open access: yesAdvanced Functional Materials, EarlyView.
Zinc‐air batteries demonstrate great potential for sustainable energy storage but face major anode‐related challenges. This review provides a mechanism‐driven overview of zinc anode interfacial issues, e.g. dendrite formation, passivation, self‐corrosion, and hydrogen evolution; and explores advances in electrode, surface, and electrolyte engineering ...
Hong Zhao   +2 more
wiley   +1 more source

Use of deferoxamine (DFO) in transfusion-dependent β-thalassemia during pregnancy: A retrospective study

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2020
Objective: To report cases of use of chelation therapy during pregnancy which resulted in favorable outcomes for the babies. Materials and methods: In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian ...
Maria Grazia Piccioni   +8 more
doaj  

Italian Society of Hematology practice guidelines for the management of iron overload in thalassemia major and related disorders

open access: yesHaematologica, 2008
New measures of iron accumulation in liver and heart (superconducting quantum inference device and magnetic resonance imaging), and oral iron chelators (deferiprone and deferasirox) are available for managing iron overload in thalassemia major. To assure
Emanuele Angelucci   +8 more
doaj   +1 more source

Metabolically programmed iron chelators [PDF]

open access: yesBioorganic & Medicinal Chemistry, 2015
Extensive structure activity relationship (SAR) studies focused on the desferrithiocin [DFT, (S)-4,5-dihydro-2-(3-hydroxy-2-pyridinyl)-4-methyl-4-thiazolecarboxylic acid] pharmacophore have led to three different DFT analogs being evaluated clinically for the treatment of iron overload diseases, for example, thalassemia.
James S. McManis   +3 more
openaire   +3 more sources

Advancing Electrochemical Nitrate Reduction: Overcoming Rate‐Limiting Bottlenecks with Copper/Cobalt Catalysts

open access: yesAdvanced Functional Materials, EarlyView.
This paper synthesizes CuO@CuCo2O4 catalysts via an emulsion hydrothermal method. Among them, CuCuCo2O4 perfectly inherits the advantages of CuO and Co3O4 and successfully connects the reactions in series. During the electrolysis process, CuO is reduced to Cu.
Jin Li   +5 more
wiley   +1 more source

Recent developments centered on orally active iron chelators

open access: yesThalassemia Reports, 2014
Over the past twenty years there has been a growing interest in the orally active iron chelators, deferiprone and deferasirox, both have been extensively studied.
Robert Hider
doaj   +1 more source

Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
Semiconducting polymer nanoparticles (SPNs) exhibit many advantageous optical and biological properties. Multimodal SPN‐based contrast agents that integrate several imaging modalities yield a wealth of information through the use of different imaging mechanisms.
Faysal A. Farah   +3 more
wiley   +1 more source

Presence of a loner strain maintains cooperation and diversity in well-mixed bacterial communities [PDF]

open access: yes, 2016
Cooperation and diversity abound in nature despite cooperators risking exploitation from defectors and superior competitors displacing weaker ones. Understanding the persistence of cooperation and diversity is therefore a major problem for evolutionary ...
Biernaskie, Jay   +3 more
core   +2 more sources

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

open access: yesAdvanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li   +7 more
wiley   +1 more source

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