Results 81 to 90 of about 1,030,253 (321)
BACKGROUND Regularly transfused people with sickle cell disease (SCD) and people with thalassaemia (who are transfusion-dependent or non-transfusion-dependent) are at risk of iron overload.
Patricia Fortin+6 more
semanticscholar +1 more source
Zinc‐air batteries demonstrate great potential for sustainable energy storage but face major anode‐related challenges. This review provides a mechanism‐driven overview of zinc anode interfacial issues, e.g. dendrite formation, passivation, self‐corrosion, and hydrogen evolution; and explores advances in electrode, surface, and electrolyte engineering ...
Hong Zhao+2 more
wiley +1 more source
Objective: To report cases of use of chelation therapy during pregnancy which resulted in favorable outcomes for the babies. Materials and methods: In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian ...
Maria Grazia Piccioni+8 more
doaj
New measures of iron accumulation in liver and heart (superconducting quantum inference device and magnetic resonance imaging), and oral iron chelators (deferiprone and deferasirox) are available for managing iron overload in thalassemia major. To assure
Emanuele Angelucci+8 more
doaj +1 more source
Metabolically programmed iron chelators [PDF]
Extensive structure activity relationship (SAR) studies focused on the desferrithiocin [DFT, (S)-4,5-dihydro-2-(3-hydroxy-2-pyridinyl)-4-methyl-4-thiazolecarboxylic acid] pharmacophore have led to three different DFT analogs being evaluated clinically for the treatment of iron overload diseases, for example, thalassemia.
James S. McManis+3 more
openaire +3 more sources
This paper synthesizes CuO@CuCo2O4 catalysts via an emulsion hydrothermal method. Among them, CuCuCo2O4 perfectly inherits the advantages of CuO and Co3O4 and successfully connects the reactions in series. During the electrolysis process, CuO is reduced to Cu.
Jin Li+5 more
wiley +1 more source
Recent developments centered on orally active iron chelators
Over the past twenty years there has been a growing interest in the orally active iron chelators, deferiprone and deferasirox, both have been extensively studied.
Robert Hider
doaj +1 more source
Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging
Semiconducting polymer nanoparticles (SPNs) exhibit many advantageous optical and biological properties. Multimodal SPN‐based contrast agents that integrate several imaging modalities yield a wealth of information through the use of different imaging mechanisms.
Faysal A. Farah+3 more
wiley +1 more source
Presence of a loner strain maintains cooperation and diversity in well-mixed bacterial communities [PDF]
Cooperation and diversity abound in nature despite cooperators risking exploitation from defectors and superior competitors displacing weaker ones. Understanding the persistence of cooperation and diversity is therefore a major problem for evolutionary ...
Biernaskie, Jay+3 more
core +2 more sources
Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li+7 more
wiley +1 more source