Results 111 to 120 of about 479,648 (301)

Elucidating Iron Metabolism through Molecular Imaging

Current Issues in Molecular Biology
Iron is essential for many physiological processes, and the dysregulation of its metabolism is implicated in the pathogenesis of various diseases.
Feifei Liao, Wenwen Yang, Linzi Long, Ruotong Yu, Hua Qu, Yuxuan Peng, Jieming Lu, Chenghuan Ren, Yueqi Wang, Changgeng Fu   +9 more
doaj   +1 more source

IRON METABOLISM IN PREGNANCY [PDF]

Obstetrical & Gynecological Survey, 1951
A, KLOPPER, S, VENTRUA
openaire   +2 more sources

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

The Floor‐Ceiling‐Chip, or 2 × 2D = Pseudo‐3D—Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell‐Adhesive Protein Micropatterns

Advanced Healthcare Materials, EarlyView.
Here, we present a novel 3D cell patterning and culture platform. The “Floor‐Ceiling‐Chip” (FC‐Chip) consists of two opposing track‐etched membranes, creating a pseudo‐3D microenvironment for the cells in between. By providing the membranes with micropatterned cell‐adhesive islands of varying geometries and sizes, the FC‐Chip enables control over cell ...
Urandelger Tuvshindorj, Francesca Giacomini, Esra Güben Kaçmaz, Tim ten Brink, Lorenzo Moroni, Zeinab Tahmasebi Birgani, Clemens van Blitterswijk, Pamela Habibović, Stefan Giselbrecht, Jan de Boer, Roman Truckenmüller   +10 more
wiley   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

Smart Molecules
Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates. In the last 3 decades, the disruption of iron homeostasis and the cytotoxic effects mediated by iron have been ...
Xinyu Tan, Man Li, Jing Chen, Gang Liu, Zhixiang Lu   +4 more
doaj   +1 more source

Integrating multi-omics techniques and in vitro experiments reveals that GLRX3 regulates the immune microenvironment and promotes hepatocellular carcinoma cell proliferation and invasion through iron metabolism pathways

Frontiers in Immunology
BackgroundHepatocellular carcinoma (HCC) is a common malignancy worldwide, and its development is closely related to abnormalities in iron metabolism. This study aims to systematically analyze changes in iron metabolism in the tumor microenvironment of ...
Yang Li, Yuan Chen, Yuan Chen, Yang Zhang, Yunsheng Fang, Yunsheng Fang, Ling Wu, Ying Zhao, Danqiong Wang, Xiaoyuan Qiao   +9 more
doaj   +1 more source

Coenzyme A corrects pathological defects in human neurons of PANK2‐associated neurodegeneration

EMBO Molecular Medicine, 2016
Pantothenate kinase‐associated neurodegeneration (PKAN) is an early onset and severely disabling neurodegenerative disease for which no therapy is available.
Daniel I Orellana, Paolo Santambrogio, Alicia Rubio, Latefa Yekhlef, Cinzia Cancellieri, Sabrina Dusi, Serena G Giannelli, Paola Venco, Pietro G Mazzara, Anna Cozzi, Maurizio Ferrari, Barbara Garavaglia, Stefano Taverna, Valeria Tiranti, Vania Broccoli, Sonia Levi   +15 more
doaj   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

P1496: TRANSFERRIN NON-CODING VARIANTS CAUSE MRNA DESTABILISATION IN CONGENITAL HYPOTRANSFERRINEMIA

HemaSphere, 2023
Xenia Ferrer, Lídia Romero-Cortadellas, Cristina Diaz-de-Heredia, Katja Moser, Ilona Kleine Budde, Mayka Sanchez   +5 more
doaj   +1 more source

Role of the liver in iron metabolism – histochemical iron identification [PDF]

, 2009
Željezo je potrebno za osnovno funkcioniranje svih stanica u organizmu sisavaca, ali posebnu važnost ima u stanicama koje proizvode hemoglobin i mioglobin. Sisavci primaju željezo isključivo putem prehrane.
Hršak, Marija
core   +2 more sources