Results 221 to 230 of about 48,493 (287)

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

Neuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng, Min Bai, Changsheng Ma, Bo Han, Mengyuan Duan, Liying Zhang, Jinfen Guo, Changku Shi, Ke Li, Maotao He   +9 more
wiley   +1 more source

Iron overload is closely associated with metabolic dysfunction-associated fatty liver disease in type 2 diabetes. [PDF]

Obesity (Silver Spring)
Qu H, Zhou L, Wang J, Tang D, Zhang Q, Shi J.   +5 more
europepmc   +1 more source

Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation

ChemistryOpen, EarlyView.
The cyclodextrin polymer is conjugated with 35 deferoxamine units and can form iron(III) complexes. The polymer exhibits significantly lower antiproliferative activity than free deferoxamine. The cyclodextrin polymer with multiple deferoxamine units may present a promising strategy for improving the efficacy of iron chelation therapies.
Roberta Panebianco, Maurizio Viale, Graziella Vecchio   +2 more
wiley   +1 more source

Supplement-driven iron overload accelerates phenotypic aging via inflammatory biomarkers: Potential counteraction through anti-inflammatory or antioxidant diets. [PDF]

Redox Biol
Li B, Ming Z, Wang Y, Zhang Y, Zhou R, Zhang C, Wu Y, Wang G, Xie H, Li Y, Li R.   +10 more
europepmc   +1 more source

C282Y and H63D Mutations in the HFE Gene Have No Effect on Iron Overload Disorders in Japan.

, 2001
Yuhta Shiono, Ritsuko Ikeda, Hisao Hayashi, Shinya Wakusawa, Fujiko Sanae, Toshikuni Takikawa, Yoshihiro Imaizumi, Motoyoshi Yano, Kentaro Yoshioka, Miwa Kawanaka, Gohtaro YAMADA   +10 more
openalex   +2 more sources

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Hydrogen Sulfide (H₂S) Metabolism, Iron Overload, and Apoptosis-Autophagy Equilibrium in Vascular Smooth Muscle Cells. [PDF]

Antioxidants (Basel)
Arif HM, Fu M, Wang R.
europepmc   +1 more source

Surface‐Engineered 2D Nanomaterials in Gas Sensors: Advancement and Challenges

Small, EarlyView.
This review article gives a detailed overview of the surface‐engineered two‐dimensional (2D) nanomaterials gas sensors, highlighting the potential of various surface engineering techniques for the design of advanced and smart gas sensors. This article covers synthesis techniques, properties and recent developments and challenges in the designing of ...
Radha Bhardwaj, Martin Pumera
wiley   +1 more source

Lessons from Beta-Thalassemia for Improving Iron Overload Monitoring and Management in Kidney Failure. [PDF]

Cureus
Nashwan AJ, Yassin M.
europepmc   +1 more source