MRI R2* and quantitative susceptibility mapping in brain tissue with extreme iron overload. [PDF]
Birkl C +7 more
europepmc +1 more source
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova +2 more
wiley +1 more source
Iron overload is not the same everywhere: Particularities of iron-metabolism gene mutations in Brazil and a proposal for the investigation and management of iron overload in this population. [PDF]
de Melo Campos P +3 more
europepmc +1 more source
Summary Introduction Pre‐operative anaemia is an established risk factor for mortality after cardiac surgery. The extent to which this risk is mediated by complications related to red blood cell transfusion remains uncertain, particularly across different age groups.
Elisabeth M. Groenewegen +23 more
wiley +1 more source
Multimodal evidence chain of iron overload, inflammation, and dysfunction: an integrated predictive model of early cardiac injury in pediatric transfusion-dependent <i>β</i>-thalassemia. [PDF]
Zhou P +5 more
europepmc +1 more source
The role of iron in normal and impaired testicular function
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source
Administration of green tea polyphenols mitigates iron-overload-induced bone loss in a β-thalassemia mouse model. [PDF]
Xu H +8 more
europepmc +1 more source
Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan +10 more
wiley +1 more source
Abstract Soils that contain swelling clay minerals (e.g., montmorillonite) expand and contract during wetting and drying, causing movement within the soil profile. This process, known as argilliturbation, can alter artefact distributions, destroy stratigraphy and complicate the interpretation of archaeological deposits.
Caroline Mather +11 more
wiley +1 more source

