Results 231 to 240 of about 1,016,828 (293)

Iron overload damages mitochondria and induces metabolic rewiring of hematopoietic stem cells toward glycolysis.

Blood
Sighinolfi S, Cassina L, Lidonnici MR, Beretta S, Stefanoni D, Storto M, Mayerhofer C, Kristiansen TA, Scadden DT, Merelli I, Boletta A, Aprile A, Ferrari G.   +12 more
europepmc   +1 more source

ALDH1a3 Protects Against Iron Overload-Induced Oxidative Stress and Mitochondrial Impairment in Renal Tubular Epithelial Cells. [PDF]

Antioxidants (Basel)
Wei T, Xiong Z, Wang T, Huang C, Luo Q, Shi R, Jia L, Liu W, Yang D, Chen Z.   +9 more
europepmc   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Utility of Native T1 Mapping for the Evaluation of Myocardial Iron Overload in Patients with Thalassemia Major. [PDF]

Tomography
Amadu AM, Contena A, Dessì A, Piscopo L, Solinas E, Turilli D, Fanni SC, Scaglione M, Masala S.   +8 more
europepmc   +1 more source

Responsive nanoheterojunctions for built‐in electric field‐promoted cascade tumor targeting and cuproptosis‐based therapy

Responsive Materials, EarlyView.
Nanoheterojunctions have been synthesized as responsive biomaterials for cascade targeting of tumor cells and mitochondria, ROS‐mediated apoptosis and Cu‐promoted cuproptosis. And drug‐device‐field integration as an advanced paradigm of tumor treatment was employed for photo‐triggered tumor cell elimination in vitro and lesion eradication in vivo ...
Zhe Liu, Yandai Lin, Xuehui Li, Fengqi Xuan   +3 more
wiley   +1 more source

Impact of iron overload on hematopoietic stem cell transplantation in pediatric patients with nonmalignant hematological disorders. [PDF]

Blood Adv
Gibson NM, Nguyen N, Amaral S, Hsu J, Haney M, Heimbruch KE, Sabulski A, Zurawel A, Davidow KA, Lind KT, Scanlon S, Alva H, Hall L, Bailey LC, Olson TS, Kwiatkowski JL.   +15 more
europepmc   +1 more source

National Policy Coherence Counts for Reducing Inequality in Global Climate and Development Agendas

Sustainable Development, EarlyView.
ABSTRACT International institutions promote policy coherence as crucial to the effective and fair implementation of global sustainability agendas, though the evidence for its benefits is slim. We present here the first systematic cross‐country dataset on the consequences of national government efforts to promote policy coherence for vulnerable groups ...
Katherine Browne, Adis Dzebo, Zoha Shawoo, Mario Cardenas, Pierrick Chalaye, Alexia Faus Onbargi, Cassilde Muhoza, Patricia Nicdao, Nokwethaba Makhanya, Navam Niles, Priyatma Singh   +10 more
wiley   +1 more source

Hereditary Hyperferritinemia-Cataract Syndrome Misdiagnosed as Iron Overload: A Case Report. [PDF]

Cureus
Güven S, Öztürk M.
europepmc   +1 more source

Perovskite‐Based Catalysts for the Oxygen Evolution Reaction: Synthesis, Device Relevant Performance, and Scale‐Up Strategies

Small, EarlyView.
Perovskites are emerging as catalysts for acidic oxygen evolution in proton exchange membrane water electrolyzers. This manuscript focuses on catalyst behavior under device‐relevant conditions, highlighting surface reconstruction, elemental utilization, and membrane electrode assembly performance. By linking materials design with electrolyzer operation,
Jala Bib Khan, Norbert Kazamer, Marco Brand, Tim Hülser, Clemens Pollerberg, Ulrich Rost   +5 more
wiley   +1 more source

Iron overload in steatotic hepatocytes drives systemic metabolic dysfunction via alterations in hepatokine production. [PDF]

J Clin Invest
Jo HJ, Kim A, Rho H, Park AK, Kim GH, Jo SJ, Yuxin H, Hong YJ, Yeon JM, Yu HC, Song MY, Park J, Jeong YH, Hong SE, Yeon HJ, Oh DY, Scherer PE, Choi CS, Lee DH, Ki SH, Kang KW, Choi M, Park BH, Bae EJ, Kim SG, Kim W, Han CY.   +26 more
europepmc   +1 more source