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Postgraduate Medicine, 1973
The variable criteria used in diagnosing hemochromatosis have resulted in considerable confusion in the literature. How does one separate the alcoholic with cirrhosis and secondary iron overload from the patient with “familial hemochromatosis” who happens to drink too much? And if phlebotomy is the way to treat hemochromatosis, why not use this therapy
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The variable criteria used in diagnosing hemochromatosis have resulted in considerable confusion in the literature. How does one separate the alcoholic with cirrhosis and secondary iron overload from the patient with “familial hemochromatosis” who happens to drink too much? And if phlebotomy is the way to treat hemochromatosis, why not use this therapy
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The Detection of Iron Overload
New England Journal of Medicine, 1982Human physiology is such that few people accumulate excess iron. Indeed, normal persons are able to control the accumulation of body iron despite ingestion of up to 5 to 10 times the normal amount.1 There are, however, two disorders in which large amounts of iron accumulate in the parenchymal cells.
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Blood, 2009
Abstract In a remarkable study in this issue of Blood, Lok and colleagues describe the genotypic and phenotypic characteristics of hereditary hemochromatosis in 42 cases in 8 distinct families of Asian origin ...
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Abstract In a remarkable study in this issue of Blood, Lok and colleagues describe the genotypic and phenotypic characteristics of hereditary hemochromatosis in 42 cases in 8 distinct families of Asian origin ...
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Iron Metabolism: Iron Deficiency and Iron Overload
Annual Review of Genomics and Human Genetics, 2000Iron is an essential cofactor in a variety of cellular processes. Except for a few unusual bacterial species, iron is indispensable for living organisms. However, free iron is toxic because of its propensity to induce the formation of dangerous free radicals. Consequently, iron balance is tightly regulated.
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Iron Absorption and Iron Overload
Clinics in Gastroenterology, 1981Powell L.W., Halliday J.W.
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Iron Chelation for Iron Overload in Thalassemia.
Metal ions in life sciences, 2019This chapter is devoted to the chelation treatment of transfusion-dependent thalassemia patients. After a brief overview on the pathophysiology of iron overload and on the methods to quantify it in different organs, the chelation therapy is discussed, giving particular attention to the chemical and biomedical requisites.
Guido Crisponi +2 more
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Melatonin: Potential Avenue for Treating Iron Overload Disorders
Ageing Research Reviews, 2022Yuhong H Zeng, Jiancheng Yang
exaly
Annales de pathologie
Iron is essential for functioning of cells and of the body as a whole. Perls staining allows the histopathological identification of iron deposits. By classifying hepatic siderosis as parenchymal, mesenchymal or mixed, it may guide the search for its etiology. HFE1 hemochromatosis is the most common siderosis.
Turlin, Bruno, Allaume, Pierre
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Iron is essential for functioning of cells and of the body as a whole. Perls staining allows the histopathological identification of iron deposits. By classifying hepatic siderosis as parenchymal, mesenchymal or mixed, it may guide the search for its etiology. HFE1 hemochromatosis is the most common siderosis.
Turlin, Bruno, Allaume, Pierre
openaire +2 more sources