Results 61 to 70 of about 22,432 (259)
Rat liver regeneration following ablation with irreversible electroporation [PDF]
PeerJ, 2016 During the past decade, irreversible electroporation (IRE) ablation has emerged as a promising tool for the treatment of multiple diseases including hepatic cancer.
Alexander Golberg +4 more
doaj +2 more sources
Sequential Irreversible Electroporation for Locally Advanced Pancreatic Cancer
Diagnostics, 2023 Pancreatic cancer is a lethal disease, with locally advanced pancreatic cancer (LAPC) having a dismal prognosis. For patients with LAPC, gemcitabine-based regimens, with or without radiation, have long been the standard of care.
Daniel Yuxuan Ong, Uei Pua
doaj +1 more source
Irreversible Electroporation of Pancreatic Tumors
, 2017 Over 95% of pancreatic cancers are exocrine tumors that bare a dismal prognosis. Although oncological outcome is best for patients presenting with nonmetastatic resectable disease, cure is rarely achieved [1]. Up to 40% of patients present with nonmetastatic disease that is considered unresectable due to vascular encasement (locally advanced pancreatic
Meijerink, Martijn R. +3 more
openaire +5 more sources
A new principle of cell sorting by using selective electroporation in a modified flow cytometer [PDF]
, 1990 When a strong electric field pulse of a few microseconds is applied to biological cells, small pores are formed in the cell membranes; this process is called electroporation.
Bakker Schut, Tom C. +2 more
core +3 more sources
DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss
Advanced Science, EarlyView.Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim +11 more
wiley +1 more source
The effects of irreversible electroporation (IRE) on nerves. [PDF]
PLoS ONE, 2011 BACKGROUND: If a critical nerve is circumferentially involved with tumor, radical surgery intended to cure the cancer must sacrifice the nerve. Loss of critical nerves may lead to serious consequences. In spite of the impressive technical advancements in
Wei Li +4 more
doaj +1 more source
Observations on the water distribution and extractable sugar content in carrot slices after pulsed electric field treatment [PDF]
, 2014 peer-reviewedThe impact of pulsed electric field (PEF) processing conditions on the distribution of water in carrot tissue and extractability of soluble sugars from carrot slices was studied.
Aguilo-Aguayo, Ingrid +5 more
core +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Applied Sciences, 2022 Background: Irreversible electroporation (IRE) is an ablation technique based on the application of short, high-voltage pulses between needle electrodes (diameter: ~1.0 × 10−3 m). A Finite Difference-based software simulating IRE treatment generally uses
Pierre Agnass +5 more
doaj +1 more source
Irreversible Electroporation in Hepatopancreaticobiliary Tumours
Canadian Association of Radiologists Journal, 2018 Hepatopancreaticobiliary tumours are often diagnosed at an advanced disease stage, in which encasement or invasion of local biliary or vascular structures has already occurred. Irreversible electroporation (IRE) is an image-guided tumour ablation technique that induces cell death by exposing the tumour to high-voltage electrical pulses.
Ruarus, A. H. +8 more
openaire +4 more sources