Results 91 to 100 of about 8,195 (166)

Enzymatic Detection and Quantification Assay of Isatin, a Putative Stress Biomarker in Blood

, 2015
Isatin is an endogenous inhibitor of monoamine oxidase B and is found in human blood and tissue. Increased levels of isatin have been linked to stress and anxiety in rodents and humans; however, the metabolism of isatin in humans is largely unknown.
Bjarne Jochimsen (1547692), Kaare Bjerregaard-Andersen (1547704), Theis Sommer (1547698), Stine Marie Simensen (1547695), Michael Etzerodt (1547689), Jan K. Jensen (474328), Patrick J. Riss (1547701), J. Preben Morth (1547707)   +7 more
core   +1 more source

A neuroprotective dose of isatin causes multilevel changes involving the brain proteome: Prospects for further research

, 2021
Isatin (indole-2,3-dione) is an endogenous regulator, exhibiting a wide range of biological and pharmacological activities. At doses of 100 mg/kg and above, isatin is neuroprotective in different experimental models of neurodegeneration.
Medvedev A.
core  

Synthesis and NMR Characterization of New Isatin Thiosemicarbazone Derivatives [PDF]

, 2017
In this research the main focus of the presentation is the synthesis of several different isatin thiosemicarbazone derivatives and their structural determination given by a 500-MHz NMR.
Susnjar, Antonia, McFadden, Hannah, Lisic, Edward C.   +2 more
core   +1 more source

Investigation Of The Inhibitory Mechanism Of Isatin Towards The Microbial Enzyme N5-Cair Synthetase

, 2017
INVESTIGATION OF THE INHIBITORY MECHANISM OF ISATIN TOWARDS THE MICROBIAL ENZYME N5-CAIR SYNTHETASE Cale C. Streeter Isatin has been identified in a diverse range of organisms, including microorganism, plants, invertebrates and vertebrates.
Streeter, Cale Charles
core   +1 more source

Synthesis and anticancer activity of new isatin-benzoic acid conjugates

, 2016
A series of new isatin-benzoic acid conjugates (9a - n) were synthesized via conjugation of isatin (3a) and its derivatives (3b - d, 4, 5 and 6) with 4-amino-5 chloro-2-ethoxybenzoic acid or 4-amino-5-(ethylsulfonyl)-2- methoxybenzoic acid by using ...
Panga, Shyam, Asres, Kaleab, Podila, Naveen Kumar, Ciddi, Veeresham   +3 more
core   +1 more source

Organocatalytic enantioselective construction of isatin-derived N-alkoxycarbonyl 1,3-aminonaphthols via sterically encumbered hydrocarbon-substituted quinine-based squaramide

, 2017
2-Adamantyl substituted quinine-squaramide catalyzed aza-Friedel–Crafts reaction of N-carbamate isatin ketimines with naphthol afforded chiral isatin-derived 1,3-aminonaphthols with excellent enantioselectivity up to greater than 99% and quantitative ...
Cihangir Tanyeli, Tanyeli, Cihangir, Karahan, SEDA, Seda Karahan   +3 more
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From Structure to Function: Isatin Derivatives as a Promising Class of Antiviral Agents.

A range of heterocyclic compounds, including Isatin (oneH-indole-2, 3-dione) and its by-products, have been shown to represent potential unit blocks in the synthesis of potential medicinal agents.
Chauhan, R, Dua, K, Kumar, A, Dalwal, V, Negi, P, Jamwal, A, Prasher, P, Sharma, S, Kapoor, VK   +8 more
core   +1 more source

Biological activities of isatin and its derivatives [PDF]

, 2005
Izatin je endogeni spoj prisutan u organizmu čovjeka koji posjeduje niz farmakoloških učinaka. Izatin djeluje kao antioksidans, sedativ i antikonvulziv. In vitro je snažni antagonist na receptorima za natrijeve ione u atriju.
SRIDHAR, SESHAIAH KRISHNAN, PANDEYA, SURENDRA NATH, SMITHA, SIVAKUMAR, JYOTI, MAYANK   +3 more
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1H‑1,2,3-Triazole Tethered Nitroimidazole–Isatin Conjugates: Synthesis, Docking, and Anti-Proliferative Evaluation against Breast Cancer

, 2018
1H-1,2,3-Triazole tethered imidazole–isatin and imidazole–isatin–thiosemicarbazone conjugates were synthesized and evaluated against MCF-7 and MDA-MB-231 cell lines.
Amit Anand (2362732), Sumit Kumar (592801), Mandeep Kaur (213886), Vipan Kumar, Shanen Perumal, Sourav Taru Saha, Vipan Kumar (828014), Sumit Kumar, Ashona Singh-Pillay (3711811), Sourav Taru Saha (4807041), Liang Gu (573034), Gabriella Palma, Ashona Singh-Pillay, Shanen Perumal (4807044), Amit Anand, Liang Gu, Parvesh Singh (774784), Mandeep Kaur, Parvesh Singh, Gabriella Palma (5796344)   +19 more
core   +1 more source

Efficient removal of Cr(VI) from aqueous solutions using graphene Oxide@Isatin-PVP composite: Synthesis, characterization, and adsorption studies

Chemistry of Inorganic Materials
Chromium (VI) is a highly toxic and persistent heavy metal ion often present in industrial effluent, presenting significant hazards to human health and the environment.
Chandrakant D. Ghugare, Nilesh V. Rathod, Jayshri S. Jadhao, Ankita Rao, Akash V. Kubade, Parikshit S. Thakare, Arun B. Patil   +6 more
doaj   +1 more source