Results 91 to 100 of about 7,251 (220)

Evaluation of the Antibacterial Activity of Isatin against Campylobacter jejuni and Campylobacter coli Strains

Applied Microbiology
Antibiotic resistance, particularly against fluoroquinolones and macrolides, has emerged globally among thermophilic Campylobacters (Campylobacter jejuni and Campylobacter coli), giving rise to concerns about the efficacy of antibiotic treatment of these
Claudia B. Barroso, Liliane M. Seki, Wagner T. C. Esteves, Michele C. Nascimento, Aurea Echevarria   +4 more
doaj   +1 more source

Synthesis and anticancer activity of new isatin-benzoic acid conjugates

, 2016
A series of new isatin-benzoic acid conjugates (9a - n) were synthesized via conjugation of isatin (3a) and its derivatives (3b - d, 4, 5 and 6) with 4-amino-5 chloro-2-ethoxybenzoic acid or 4-amino-5-(ethylsulfonyl)-2- methoxybenzoic acid by using ...
Panga, Shyam, Asres, Kaleab, Podila, Naveen Kumar, Ciddi, Veeresham   +3 more
core   +1 more source

Molecular docking and synthesis of N-alkyl-isatin-3-imino aromatic amine derivatives and their antileishmanial and cytotoxic activities

Research in Pharmaceutical Sciences
Background and purpose: Isatin derivatives have excited attention due to their biological attractions, especially, anticancer properties. Isatin analogs such as semaxanib and sunitinib were exposed to tyrosine kinase inhibitory properties.
Farshid Hassanzadeh, Seyed Hossein Hejazi, Elham Jafari, Atefeh Mohammadi fard, Hojjat Sadeghi-aliabadi   +4 more
doaj   +1 more source

N-Alkyl-Substituted Isatins Enhance P2X7 Receptor-Induced Interleukin-1β Release from Murine Macrophages

Mediators of Inflammation, 2016
Extracellular adenosine 5′-triphosphate (ATP) activates the P2X7 receptor channel to induce the rapid release of the proinflammatory cytokine, interleukin- (IL-) 1β, from macrophages. Microtubule rearrangements are thought to be involved in this process.
Ronald Sluyter, Kara L. Vine
doaj   +1 more source

Chemical structure of the isatin derivative RMNC6.

, 2016
Chemical structure of the isatin derivative RMNC6.
Rita Meleddu (847391), Simona Distinto (847393), Giulia Bianco (847394), Luis Menéndez-Arias (847396), Francesca Esposito (847392), Stefano Alcaro (152511), Enzo Tramontano (847397), Angela Corona (847390), Elias Maccioni (847395), Takashi Masaoka (542370), Stuart F. J. Le Grice (6613)   +10 more
core   +1 more source

Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling

, 2017
Hatem A Abdel-Aziz,1 Wagdy M Eldehna,2 Adam B Keeton,3 Gary A Piazza,3 Adnan A Kadi,4 Mohamed W Attwa,4 Ali S Abdelhameed,4 Mohamed I Attia4,5 1Department of Applied Organic Chemistry, National Research Centre, Giza, 2Department of Pharmaceutical ...
Keeton AB, Abdel-Aziz HA, Eldehna WM, Attwa MW, Attia MI, Abdelhameed AS, Piazza GA, Kadi AA   +7 more
core  

Conformational stabilization of isatin Schiff bases – biologically active chemical probes

, 2017
Two ways of conformation stabilization for isatin Schiff bases (group of biologically active compounds) are reported here: complexation with metals that stabilize E-conformer and substitution in the 4th position of isatin core stabilizing Z-form.
Pavel B. Davidovich, Dmitriy N. Nikolaev, Sergey N. Smirnov, Andrey S. Smirnov, Vlad V. Gurzhiy, Alexander V. Garabadzhiu, Vitaliy S. Suslonov   +6 more
core   +1 more source

THE SYNTHESIS OF NEW SPIROLACTONES FROM SUBSTITUTED ISATINS [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2015
Interaction of N-ethyl isatin 3 with dimethyl acetylenedicarboxylate in the presence triphenylphosphine has led to good selectivity of methyl 1'-ethyl-4-methoxy-2',5-dioxo-5H-spiro[furan-2,3'-indoline]-3-carboxylate 4 formation.
Natalia Sucman, Vsevolod Pogrebnoi, Mykola Obushak, Elena Melnic, Victor Kravtsov, Fliur Macaev   +5 more
doaj  

Spectroscopic studies on Isatin-3-Semicarbazone and Isatin-3-Thiosemicarbazone

Global Journal of Pure and Applied Sciences, 2004
The configurations of semi-and thiosemicarbazone derivatives of isatin are assigned by means of 1H and 13C NMR Spectroscopy including NOE difference spectra, IR and electronic spectral data of these compounds are also reported and discussed. The electron impact (EI), fast atom bombardment (FAB) and negative ion chemical ionization (NICI) mass spectra ...
openaire   +3 more sources

Evaluation of Diuretic Activity of Isatin Derivatives in Wistar Rats

, 2013
In the present studies we have synthesized ten derivatives of novel isatin-3-[N2-(2-benzalaminothiazol-4-yl)]hydrazone and characterized by the help of physical and spectral data.
J. Venkateshwar Rao, K. Umasankar, E. Venkateshwarlu, B.S. Sharvana Bhava   +3 more
core   +1 more source