Results 71 to 80 of about 8,195 (166)

Overview of Photochemical Reactions for the Synthesis of Aza and Oxa‐Spirocyclic Compounds Under Visible Light Irradiation

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review presents the visible‐light‐mediated photochemical reaction for the synthesis of aza, oxa, and aza–oxa spirocyclic compounds via photoinduced electron transfer (PET), hydrogen atom transfer (HAT), single‐electron transfer (SET), or energy transfer (EnT) pathways.
Annu Bhardwaj, Shivangi Jaiswal, Khushboo Bhardwaj, Swapnil Sharma, Jaya Dwivedi   +4 more
wiley   +1 more source

Recent advances in Isatin chemistry: Classical and modern synthetic strategies, mechanistic perspective, and biological applications of a privileged scaffold

Results in Chemistry
Isatin (1H-indole-2,3-dione) is a privileged scaffold that has attracted sustained interest because of its remarkable synthetic versatility and broad range of biological activities.
Seyed Mohammadreza Alavi, Mosayeb Akbari, Elham Mohammadi Mehr, Soodabeh Davaran, Rozita Yazzaf, Saghi Sepehri, Mohammad Mahdavi   +6 more
doaj   +1 more source

1-Benzyl-5-methylindoline-2,3-dione

IUCrData, 2016
The title compound, C16H13NO2, is an isatin (indole-2,3-dione) derivative. The isatin moiety is almost planar with an r.m.s. deviation of 0.022 Å, and its mean plane makes a dihedral angle of 74.19 (12)° with the benzyl ring.
N. Sharmila, T. V. Sundar, G. Satish, P. Venkatesan   +3 more
doaj   +1 more source

Síntese e caracterização estrutural do ligante isatina-3-(N4-benziltiossemicarbazona) e do seu complexo de mercúrio(II) Synthesis and structural characterization of the ligand isatin-3-(N4-benzylthiosemicarbazone) and its mercury(II) complex

Química Nova, 2010
The reaction of 4-(phenyl)thiosemicarbazide with isatin yielded a new ligand, isatin-3-(N4-benzylthiosemicarbazone). Isatin-3-(N4-benzylthiosemicarbazone) deprotonated in ethanol/KOH reacts with an ethanolic solution of Hg(NO3)2 to give a mercury complex.
Alexandra de Souza Fonseca, Gisele Louro Peres, Tomás Garcia Storino, Leandro Bresolin, Vanessa Santana Carratu, Vinícius F. Giglio, Estela dos Reis Crespan, Manfredo Hörner   +7 more
doaj   +1 more source

Chemical structure of the isatin derivative RMNC6.

, 2016
Chemical structure of the isatin derivative RMNC6.
Rita Meleddu (847391), Simona Distinto (847393), Giulia Bianco (847394), Luis Menéndez-Arias (847396), Francesca Esposito (847392), Stefano Alcaro (152511), Enzo Tramontano (847397), Angela Corona (847390), Elias Maccioni (847395), Takashi Masaoka (542370), Stuart F. J. Le Grice (6613)   +10 more
core   +1 more source

Computational, In Vitro, and In Vivo Evaluation of Benzimidazole–Pyrazole Hybrid Scaffolds as Multi‐Target Anti‐Ulcer Agents

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The hybrid pharmacophore approach involves the combination of benzimidazole‐pyrazole moieties to form multi‐functional anti‐ulcer compounds. Molecular modeling and biological evaluations show significant proton pump inhibition, anti‐inflammatory action, antioxidant property, and remarkable prevention of gastric ulcers.
Hafiz Aamir Ali Kharl, Abdul Malik, Humaira Nadeem, Mohammad Shamsul Ola, Sara Aiman, Arif Ullah Khan, Muhammad Akmal Farooq, Humaira Muzaffar, Syed Muzzammil Masaud   +8 more
wiley   +1 more source

Isatin-Derived Compounds as Carbon Steel Corrosion Inhibitors in Highly Saline Media

International Journal of Electrochemical Science, 2013
Carbon steel corrosion in CO2-saturated solutions, simulating the produced water generated in oil and gas extraction, was investigated using weight loss, electrochemical measurements and surface characterization. The effectiveness of two isatin compounds,
A.B. da Silva, J.A.C.P. Gomes, E. D’Elia, M.J.C. Rezende, A.C. Pinto, B.N.M. Silva, B.V. Silva   +6 more
doaj   +1 more source

[[alternative]]Isatin-β-thiosemicarbazones as potent herpes simplex virus inhibitors

, 2011
[[abstract]]A series of isatin-beta-thiosemicarbazones have been designed and evaluated for antiviral activity against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) in a plaque reduction assay.
Kang, IJ;Wang, LW;Hsu, TA;Yueh, A;Lee, CC;Lee, YC;Lee, CY;Chao, YS;Shih, SR;Chern, JH
core   +1 more source

Effects and mechanism of action of isatin, a MAO inhibitor, on in vivo striatal dopamine release [PDF]

Isatin is an endogenous indole that inhibits monoamine oxidase (MAO), being more selective for MAO-B than MAO-A isoform. By inhibiting MAO, isatin increases dopamine levels in the brain and, in animal models of Parkinson’s disease (PD) isatin is able to ...
Durán Barbosa, Rafael, Alfonso Pallarés, Miguel, Justo Cousiño, Lorenzo Antonio, Fajardo Blanco, Daniel, Ferreira Faro, Lilian Rosana   +4 more
core   +1 more source

Development of Synergetic Combinations of a Novel Apoptosis Inducer with AKT and Hsp90 Selective Inhibitors Targeting Hormone-Sensitive and Hormone-Resistant Breast Cancer Cells

Proceedings
Introduction: The design and development of antitumor compounds based on an isatin core led to the synthesis of 1-substituted isatin-5-sulfonamides with potent antiproliferative activity [...]
Diana I. Salnikova, Stepan K. Krymov, Danila V. Sorokin, Fedor B. Bogdanov, Olga E. Andreeva, Alvina I. Khamidullina, Andrey E. Shchekotikhin, Alexander M. Scherbakov   +7 more
doaj   +1 more source