Cytotoxicity study of some indophenines and isatin derivatives
Eight indophenines were synthesized for the interest of studying biological activity especially for cytotoxicity. The cytotoxicity of some indophenines and some isatin derivatives was studied by the brine shrimp lethality bioassay.
Md. Mahbubul Hoque, Md. Rabiul Islam
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THE SYNTHESIS OF NEW SPIROLACTONES FROM SUBSTITUTED ISATINS [PDF]
Interaction of N-ethyl isatin 3 with dimethyl acetylenedicarboxylate in the presence triphenylphosphine has led to good selectivity of methyl 1'-ethyl-4-methoxy-2',5-dioxo-5H-spiro[furan-2,3'-indoline]-3-carboxylate 4 formation.
Natalia Sucman +5 more
doaj
Review On Isatin and its Antidiabetic Isatin Scaffolds
Isatin (1H-indole-2,3-dione) is a well-known heterocyclic compound that has gained considerable attention in medicinal chemistry due to its broad range of biological activities. The molecule possesses a bicyclic structure consisting of a benzene ring fused with a five-membered heterocyclic ring containing two carbonyl groups at the C-2 and C-3 ...
openaire +2 more sources
Chromium (VI) is a highly toxic and persistent heavy metal ion often present in industrial effluent, presenting significant hazards to human health and the environment.
Chandrakant D. Ghugare +6 more
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A Survey of Isatin Hybrids and their Biological Properties
The emergence of diverse infections worldwide, which is a serious global threat to human existence, necessitate the urgent development of novel therapeutic candidates that can combat these diseases with efficacy. Isatin, a secondary metabolite from tryptophan is considered a privileged scaffold and favorable pharmacophore with a unique structural ...
Vanessa Asoh Shu +2 more
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Design, synthesis, and anti-inflammatory evaluation of new isatin azo disperse dyes: computational studies, molecular docking, and printing performance on polyester fabrics. [PDF]
Hekal HA +5 more
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Synthesis of azole-linked <i>s</i>-triazine-isatin molecular architectures as nanoscale DNA-targeting agents: a combined spectroscopic and computational study. [PDF]
Mushtaq A, Nazia B, Naseer MM.
europepmc +1 more source
NMR spectroscopic and computational analysis of <i>E</i>/<i>Z</i> isomerism in imines derived from isatin. [PDF]
Gonzalez-Oñate A +4 more
europepmc +1 more source
Synthesis and Biological Evaluation of Imidazopyridine-Isatin Hybrids as Inhibitors of <i>Leishmania major</i> Growth. [PDF]
El Hassab MA +12 more
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A sustainable one-pot multi-component approach toward the synthesis of symmetric and unsymmetrical spiro heterocycles catalyzed by the Brønsted acidic ionic liquid [CMMIM][BF<sub>4</sub>]. [PDF]
Begum R, Maiti B.
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