Results 61 to 70 of about 8,195 (166)

On‐DNA Nitro Reduction for Use in DNA‐Encoded Library Synthesis: Methods, Applications, and Challenges

Asian Journal of Organic Chemistry, Volume 15, Issue 10, October 2026.
Reducing aryl nitro groups provides DNA‐linked anilines for use in benzimidazole synthesis and other scaffold‐forming reactions during the construction of DNA‐encoded libraries. This review examines transfer hydrogenation and Fe(II)‐, dithionite/viologen‐, diboron‐, and Pd‐based methods, focusing on how reaction efficiency, chemoselectivity, DNA ...
Yeongjoo Suh, Yeongyeon Lee, Yujin Han, Hongjun Jeon   +3 more
wiley   +1 more source

Iodine-catalyzed Synthesis, Antibacterial, and Antioxidant Activity of Isatin Derivatives

Indonesian Journal of Chemistry
Isatin is a unique compound with many bioactivities such as antiviral, anti-HIV, antitumor, anti-inflammatory, anticonvulsant, and antifungal. In this study, isatin derivatives were synthesized with an iodine catalyst and tested for antibacterial and ...
Antonius Herry Cahyana, Agus Rimus Liandi, Yosua Ongkowidjawa   +2 more
doaj   +1 more source

A Neuroprotective Dose of Isatin Causes Multilevel Changes Involving the Brain Proteome: Prospects for Further Research

, 2020
Isatin (indole-2,3-dione) is an endogenous regulator, exhibiting a wide range of biological and pharmacological activities. At doses of 100 mg/kg and above, isatin is neuroprotective in different experimental models of neurodegeneration.
Alexei Medvedev, Olga Buneeva, Leonid Kurbatov, Alexis Ivanov, Arthur Kopylov, Olga Tikhonova, Victor Zgoda   +6 more
core   +1 more source

A Green Sample Preparation Procedure for Determining Proline in Honey and Wine by Visible Molecular Absorption Spectrophotometry After Microwave‐Assisted Derivatization

ChemistrySelect, Volume 11, Issue 38, 13 October 2026.
A green, simple, and rapid method quantifies proline in wine and honey. Microwave‐assisted derivatization and ultrasonic cooling drastically reduced reaction and cooling times. The validated spectrophotometric method shows high accuracy (95.7%–109.4% recovery) and is an eco‐friendly alternative, confirmed by the AGREEPrep (Analytical GReenness metric ...
Amanda de Aguiar Barreto, Maryellen Batista dos Santos, Alexia Tamyres Moreira Silva Barberino, Lara Pinto de Araújo, Madson Moreira Nascimento, Raildo Mota de Jesus, Ivon Pinheiro Lôbo   +6 more
wiley   +1 more source

Microwave Synthesis, Characterization, and Antimicrobial Activity of Some Novel Isatin Derivatives

Journal of Chemistry, 2015
Three series of isatin derivatives [3-hydrazino, 3-thiosemicarbazino, and 3-imino carboxylic acid derivatives] were synthesized employing microwave irradiation.
Ayman El-Faham, Wael N. Hozzein, Mohammad A. M. Wadaan, Sherine N. Khattab, Hazem A. Ghabbour, Hoong-Kun Fun, Mohammed Rafiq Siddiqui   +6 more
doaj   +1 more source

Synthesis, Anti‐Leishmania amazonensis Activity, Cytotoxicity, and Molecular Docking of Anthranilate–Naphthoquinone Hybrids

ChemistrySelect, Volume 11, Issue 40, 27 October 2026.
New anthranilate–naphthoquinone hybrids display potent inhibition of Leishmania (L.) amazonensis with low host cell toxicity. Molecular docking reveals key interactions with TR, GP63, and PTR1, suggesting a multitarget mechanism that contributes to parasite death.
Eduardo Miranda da Silva Magesfeste, Lidilhone Hamerski, Diego Mendes Nunes, Ana Paula Sotero da Silva Ribeiro, Elvira Maria Saraiva, Magaly Girão Albuquerque, Camilo Henrique da Silva Lima, Bárbara Vasconcellos da Silva   +7 more
wiley   +1 more source

Defects Induced Instability of Perovskite Solar Cells

Advanced Energy and Sustainability Research, Volume 7, Issue 9, September 2026.
Defect passivation and grain‐size engineering in perovskite films are achieved through precursor additives, antisolvent additives, interfacial modification, light treatment, surface polishing, and temperature treatment. The synergistic effects suppress defect states and enhance film quality, providing insights into effective strategies for improving ...
Davoud Dastan, Fariba Tajabadi, Mohammad Sajedi Alvar, Mustafa Kareem, Amirhossein Rahimi, Mahboubeh Hadadian, Mohammad Hatamvand, Zhicheng Shi, Yingxin Chen, Lin Tao, Antonio Abate, Xi‐Tao Yin, Hanieh Helli, Mohammad Khaja Nazeeruddin   +13 more
wiley   +1 more source

Synthesis and Supramolecular Organization of 5-(4-Alkylphenyl)isatin

, 2016
The synthesis of a homologous series of 5-(4-alkylphenyl)isatin derivatives, as well as the crystal structure and DFT studies of the respective hexyl derivative are presented, constituting the first examples of a new family of supramolecular bilayer ...
Dirk Blunk (2179042), Jan H. Porada (2179044), Jörg Neudörfl (2179046)   +2 more
core   +2 more sources

Enantioselective Solvent-Free Synthesis of 3-Alkyl-3-hydroxy-2-oxoindoles Catalyzed by Binam-Prolinamides

Molecules, 2015
BINAM-prolinamides are very efficient catalyst for the synthesis of non-protected and N-benzyl isatin derivatives by using an aldol reaction between ketones and isatins under solvent-free conditions.
Abraham Bañn-Caballero, Jesús Flores-Ferrándiz, Gabriela Guillena, Carmen Nájera   +3 more
doaj   +1 more source

Antibacterial potentials of pillar[5]arene, pillar[4]arene[1]quinone derivative and their isatin inclusion complexes

, 2023
Host–guest complexation of decamethoxypillar[5]arene and difunctionalized pillar[4]arene[1]quinone with isatin were demonstrated by 1H NMR titration experiments. The antibacterial potentials of isatin, decamethoxypillar[5]arene, difunctionalized pillar[4]
Dhandapani Kavitha (14652014), Sekar JothiNayaki (14652002), Ravindhiran Ramya (14652005), Sankar Srividhya (9453318), Murugan Arunachalam (6316799), Krishnamurthy Ramya (14652008), Sivarajan Karthiga (14652011), Jeyavelraman Kiruthika (9453315)   +7 more
core   +1 more source