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Design, synthesis, docking, and antidepressant activity evaluation of isatin derivatives bearing Schiff bases [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Depression is a prevalent psychiatric disorder. Treatment of depression is still a challenge due to the lack of response of some patients to a variety of available medications and side effects.
Azadeh Mesripour +3 more
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Anticancer Compounds Based on Isatin-Derivatives: Strategies to Ameliorate Selectivity and Efficiency [PDF]
Frontiers in Molecular Biosciences, 2021 In this review we compare and discuss results of compounds already reported as anticancer agents based on isatin-derivatives, metalated as well as non-metallated.
Raphael Enoque Ferraz de Paiva +4 more
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Pharmaceuticals, 2022 Isatin (1H indole 2, 3-dione) is a heterocyclic, endogenous lead molecule recognized in humans and different plants. The isatin nucleus and its derivatives are owed the attention of researchers due to their diverse pharmacological activities such as ...
Rameshwar S. Cheke +11 more
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Cytotoxicity study of some indophenines and isatin derivatives [PDF]
Bangladesh Journal of Pharmacology, 2008 Eight indophenines were synthesized for the interest of studying biological activity especially for cytotoxicity. The cytotoxicity of some indophenines and some isatin derivatives was studied by the brine shrimp lethality bioassay.
Md. Mahbubul Hoque, Md. Rabiul Islam
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Solvatochromism of isatin based Schiff bases: An LSER and LFER study [PDF]
Journal of the Serbian Chemical Society, 2016 The derivatives of isatin have already been reported to show a variety of biological activities. However, there has been no report on solvatochromic effect of isatin derivatives so far, and that could be of interest to study and relate to their ...
Brkić Dominik R. +6 more
doaj +1 more source
Cytotoxicity study of dimethylisatin and its heterocyclic derivatives
Bangladesh Journal of Pharmacology, 2007 Isatin derivatives are bioactive molecules. To study the cytotoxicity and eventually the anticancer activities against cancer cell lines, a series of dimethyl-substitituted isatin derivatives (4-8) starting from isatin thiosemicarbazones (3) had been ...
Mohammad Mamun Hossain +3 more
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Iraqi Journal of Pharmaceutical Sciences, 2023 Till now, isatin derivatives have received a lot of interest in organic and medicinal chemistry due to their significant biological and pharmacological activities.
Mustafa Mahmood Mukhlif +1 more
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The impact of isatin derivatives on antibiotic production by Streptomyces hygroscopicus CH-7 [PDF]
Hemijska Industrija, 2016 The effect of isatin derivatives as a nitrogen source on antibiotic (Hexaene H-85 and Azalomycine B) production by Streptomyces hygroscopicus CH-7 was studied.
Ćirić Jovan T. +5 more
doaj +1 more source
Research in Pharmaceutical Sciences, 2018 Due to resistance of some epileptic patients to the current medications and the general incidence of severe side effects of these drugs, development and discovery of novel antiepileptic drugs is crucial.
Marzieh Rahmani Khajouei +3 more
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Synthesis of Isatin and its derivatives containing heterocyclic compounds
Journal of the Turkish Chemical Society, Section A: Chemistry, 2021 Isatin or 1H-indole-2,3-dione or 2,3-dioxindole is an indole derivative. Isatin and its analogs are synthetically useful substances where they may be utilized for the production of a broad range of heterocyclic molecules, which are depicting a wide reach
Pratibha MİSHRA +4 more
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