Results 11 to 20 of about 3,007 (178)

Microwave Synthesis, Characterization, and Antimicrobial Activity of Some Novel Isatin Derivatives

Journal of Chemistry, 2015
Three series of isatin derivatives [3-hydrazino, 3-thiosemicarbazino, and 3-imino carboxylic acid derivatives] were synthesized employing microwave irradiation.
Ayman El-Faham, Wael N. Hozzein, Mohammad A. M. Wadaan, Sherine N. Khattab, Hazem A. Ghabbour, Hoong-Kun Fun, Mohammed Rafiq Siddiqui   +6 more
doaj   +1 more source

Room Temperature, Open-Flask C–P Bond-Formation on Water under Catalyst-Free Conditions

SynOpen, 2018
A catalyst-free C–P bond-formation in an open flask at room temperature between isatin derivatives and phosphorus surrogates on water is described. Isatin derivatives possessing different substitutes underwent C–P coupling reaction with a variety of ...
Rakhee Choudhary, Rekha Bai, Pratibha Singh, Mahesh C. Sharma, Satpal Singh Badsara   +4 more
doaj   +1 more source

Synthesis and spectroscopic analysis of Schiff Bases of Imesatin and Isatin derivatives

Journal of Applied Sciences and Environmental Management, 2016
A series of new Schiff bases of Imesatin and Isatin derivatives which have been previously prepared from the reaction of Hydrazine monohydrate, p-phenylenediamine and 4,4- diaminodiphenylmethane with Isatin were reported.
Olubunmi S. Oguntoye, Abdulmumeen A. Hamid, Gabriel S. Iloka, Sunday O. Bodede, Samson O. Owalude, Adedibu C. Tella   +5 more
doaj   +1 more source

Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives [PDF]

Journal of the Serbian Chemical Society, 2014
The isatin derivatives, Schiff bases, were synthesized by the reaction of isatin and various substituted primary amines and characterized by several spectroscopic methods.
Šekularac Gavrilo M., Nikolić Jasmina B., Petrović Predrag, Bugarski Branko, Đurović Boban, Drmanić Saša Ž.   +5 more
doaj   +1 more source

Theoretical and experimental prediction of corrosion inhibition efficiency of isatin and its derivatives by DFT calculations and weight loss method: A comparative study [PDF]

Journal of the Serbian Chemical Society
The corrosion inhibition performance of isatin and its N1/C5 substituted derivatives were analyzed by DFT calculation (B3LYP, 6311g, dp) in gas phase and solvation method with the help of Gaussian 09W and Gaussian 16.
Joseph Xavier Raj Jone Celestina, Shenbagapushpam Muthumanickam, Vincent Arul Deepa, Shanmugaraj Priyadharsani, Raj Chakkaravarthy, Rajamohan Satheesh, Viruthachalam Ramasamy Raja   +6 more
doaj   +1 more source

Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli Derivatives

Tikrit Journal of Pure Science, 2023
In this work, a series of novel Mannich's bases incorporated with Ibuprofen core and Biginelli derivatives have been reported. The synthesis process was dependent on linking Ibuprofen hydrazone with Isatin to Biginelli derivatives via methylene group of
Layth W. Abdullah, Hanaa K.Saleh, Mustafa R. Aeyyd   +2 more
doaj   +1 more source

Computational Screening and Synthesis of Some Isatin-Thiadiazole Hybrids Potentially Targeting Diabetes

Chemistry Proceedings
This study explores the design, synthesis and preliminary in silico screening of novel thiadiazole-isatin hybrid derivatives targeting diabetes mellitus.
Monika, Nishtha Shalmali, Priyanshu
doaj   +1 more source

Electronic structure, reactivity, and predicted biological activity of halogenated isatin-pyridine Schiff bases: a DFT study [PDF]

Pharmacia
Isatin derivatives have been at the forefront of pharmaceutical research, displaying a wide range of biological activities, including antioxidant, antimicrobial, and anticancer properties. In this study, twelve isatin-pyridine Schiff bases were evaluated
Nikolay Toshev, Armina Abdollahi, Kaloyan Mihalev, Ivelin Iliev, Yordanka Uzunova, Vassil Delchev, Nadya Agova, Svetlana Georgieva   +7 more
doaj   +3 more sources

Synthesis and in vitro cytotoxicity evaluation of isatin-pyrrole derivatives against HepG2 cell line

Open Chemistry, 2021
This paper reports the synthesis and in vitro cytotoxicity evaluation of isatin-pyrrole derivatives 5–8, obtained from the appropriate isatins with pyrrole, with good yields and purity.
Santoso Mardi, Fadlan Arif, Fahmi Muhammad Riza Ghulam, Rahmayanti Ardhana   +3 more
doaj   +1 more source

Molecular docking and synthesis of N-alkyl-isatin-3-imino aromatic amine derivatives and their antileishmanial and cytotoxic activities

Research in Pharmaceutical Sciences
Background and purpose: Isatin derivatives have excited attention due to their biological attractions, especially, anticancer properties. Isatin analogs such as semaxanib and sunitinib were exposed to tyrosine kinase inhibitory properties.
Farshid Hassanzadeh, Seyed Hossein Hejazi, Elham Jafari, Atefeh Mohammadi fard, Hojjat Sadeghi-aliabadi   +4 more
doaj   +1 more source