Results 21 to 30 of about 660,493 (200)

Synthesis, Reaction and Biological Importance of Isatin Derivatives [PDF]

, 2022
Isatin is a heterocyclic nitrogen compound that has attracted much interest in recent years due to its diverse biological and pharmacological activities.
Mohammed G. A. Al-Khuzaie, Ahmed Jalil Al-Safi, Fahad, Mahmood M., Mahmood M. Fahad, Al-Safi, Ahmed Jalil, Al-Khuzaie, Mohammed G. A.   +5 more
core   +1 more source

Evaluation of Diuretic Activity of Isatin Derivatives in Wistar Rats [PDF]

, 2013
In the present studies we have synthesized ten derivatives of novel isatin-3-[N2-(2-benzalaminothiazol-4-yl)]hydrazone and characterized by the help of physical and spectral data.
J. Venkateshwar Rao, K. Umasankar, E. Venkateshwarlu, B.S. Sharvana Bhava   +3 more
core   +1 more source

Synthesis and spectroscopic analysis of Schiff Bases of Imesatin and Isatin derivatives

Journal of Applied Sciences and Environmental Management, 2016
A series of new Schiff bases of Imesatin and Isatin derivatives which have been previously prepared from the reaction of Hydrazine monohydrate, p-phenylenediamine and 4,4- diaminodiphenylmethane with Isatin were reported.
Olubunmi S. Oguntoye, Abdulmumeen A. Hamid, Gabriel S. Iloka, Sunday O. Bodede, Samson O. Owalude, Adedibu C. Tella   +5 more
doaj   +1 more source

Room Temperature, Open-Flask C–P Bond-Formation on Water under Catalyst-Free Conditions

SynOpen, 2018
A catalyst-free C–P bond-formation in an open flask at room temperature between isatin derivatives and phosphorus surrogates on water is described. Isatin derivatives possessing different substitutes underwent C–P coupling reaction with a variety of ...
Rakhee Choudhary, Rekha Bai, Pratibha Singh, Mahesh C. Sharma, Satpal Singh Badsara   +4 more
doaj   +1 more source

Effect of Substituents on the Biological Activity of Isatin Hybrids – A SAR Study

, 2023
: Isatin (2,3-dioxindole) is a benzopyrrole derivative that belongs to a large class of heterocyclic chemicals. Isatin derivatives are essential synthetic substrates that can be utilized as starting materials to build a wide range of heterocycles with ...
Sakshi Soam, Sreela Dasgupta
core   +1 more source

Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics [PDF]

, 2002
Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity ...
Hadfield, Peter S., Page, Michael I., Casey, Lorraine A., Vilanova, Bartholomew, Galt, Ronald H. B.   +4 more
core   +4 more sources

Isatin Derivatives as Inhibitors of Microtubule Assembly [PDF]

, 2008
This thesis describes the rationale, design, and syntheses of derivatives of isatin (1-H-indole-2,3-dione). Isatin was identified, during a high throughput screen of 10,000 compounds, as a potential scaffold for microtubule-destabilizing agents ...
Beckman, Karen
core   +1 more source

Theoretical and experimental prediction of corrosion inhibition efficiency of isatin and its derivatives by DFT calculations and weight loss method: A comparative study [PDF]

Journal of the Serbian Chemical Society
The corrosion inhibition performance of isatin and its N1/C5 substituted derivatives were analyzed by DFT calculation (B3LYP, 6311g, dp) in gas phase and solvation method with the help of Gaussian 09W and Gaussian 16.
Joseph Xavier Raj Jone Celestina, Shenbagapushpam Muthumanickam, Vincent Arul Deepa, Shanmugaraj Priyadharsani, Raj Chakkaravarthy, Rajamohan Satheesh, Viruthachalam Ramasamy Raja   +6 more
doaj   +1 more source

Computational Screening and Synthesis of Some Isatin-Thiadiazole Hybrids Potentially Targeting Diabetes

Chemistry Proceedings
This study explores the design, synthesis and preliminary in silico screening of novel thiadiazole-isatin hybrid derivatives targeting diabetes mellitus.
Monika, Nishtha Shalmali, Priyanshu
doaj   +1 more source

Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli Derivatives

Tikrit Journal of Pure Science, 2023
In this work, a series of novel Mannich's bases incorporated with Ibuprofen core and Biginelli derivatives have been reported. The synthesis process was dependent on linking Ibuprofen hydrazone with Isatin to Biginelli derivatives via methylene group of
Layth W. Abdullah, Hanaa K.Saleh, Mustafa R. Aeyyd   +2 more
doaj   +1 more source