Results 31 to 40 of about 1,535,483 (232)
Bis-isatin derivatives: design, synthesis, and biological activity evaluation as potent dimeric DJ-1 inhibitors [PDF]
Acta Pharmacol Sin, 2021 Xiao-bing Chen +9 more
semanticscholar +2 more sources
Isatin Derivatives and Their Antiviral Properties Against Arboviruses: A Review
Mini-Reviews in Medicinal Chemistry, 2018 Arboviruses have been spreading rapidly throughout the Western Hemisphere in recent decades. Among the arboviruses with high morbidity and mortality are the members of the Alphavirus and Flavivirus genera.
Lindomar J. Pena +5 more
core +3 more sources
Archiv der Pharmazie, 2023 Merging isatin and arylhydrazone moieties constitutes an efficient strategy to access new potential anticancer derivatives. Consequently, 14 hydrazone‐isatin derivatives were synthesized and evaluated for their antiproliferative activity against the NCI ...
Marwa F. Ahmed +6 more
semanticscholar +1 more source
Cytotoxicity study of dimethylisatin and its heterocyclic derivatives
Bangladesh Journal of Pharmacology, 2007 Isatin derivatives are bioactive molecules. To study the cytotoxicity and eventually the anticancer activities against cancer cell lines, a series of dimethyl-substitituted isatin derivatives (4-8) starting from isatin thiosemicarbazones (3) had been ...
Mohammad Mamun Hossain +3 more
doaj +2 more sources
Solvatochromism of isatin based Schiff bases: An LSER and LFER study [PDF]
Journal of the Serbian Chemical Society, 2016 The derivatives of isatin have already been reported to show a variety of biological activities. However, there has been no report on solvatochromic effect of isatin derivatives so far, and that could be of interest to study and relate to their ...
Brkić Dominik R. +6 more
doaj +1 more source
Iraqi Journal of Pharmaceutical Sciences, 2023 Till now, isatin derivatives have received a lot of interest in organic and medicinal chemistry due to their significant biological and pharmacological activities.
Mustafa Mahmood Mukhlif +1 more
doaj +1 more source
Synthesis of Isatin and its derivatives containing heterocyclic compounds
Journal of the Turkish Chemical Society, Section A: Chemistry, 2021 Isatin or 1H-indole-2,3-dione or 2,3-dioxindole is an indole derivative. Isatin and its analogs are synthetically useful substances where they may be utilized for the production of a broad range of heterocyclic molecules, which are depicting a wide reach
Pratibha MİSHRA +4 more
doaj +1 more source
Research in Pharmaceutical Sciences, 2018 Due to resistance of some epileptic patients to the current medications and the general incidence of severe side effects of these drugs, development and discovery of novel antiepileptic drugs is crucial.
Marzieh Rahmani Khajouei +3 more
doaj +1 more source
Room Temperature, Open-Flask C–P Bond-Formation on Water under Catalyst-Free Conditions
SynOpen, 2018 A catalyst-free C–P bond-formation in an open flask at room temperature between isatin derivatives and phosphorus surrogates on water is described. Isatin derivatives possessing different substitutes underwent C–P coupling reaction with a variety of ...
Rakhee Choudhary +4 more
doaj +1 more source
Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review
Al Mustansiriyah Journal of Pharmaceutical Sciences, 2022 Isatin is a heterocyclic molecule that belongs to one of the most important classes of organic compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently attracted a lot of attention in medicinal chemistry. Isatin, itself,
May Mohammed Jawad Al-Mudhafar +2 more
semanticscholar +1 more source