Results 41 to 50 of about 3,007 (178)

Synthesis of Spiro Heterocyclic Compounds

E-Journal of Chemistry, 2010
Reaction of isatin with acetophenone derivatives gave 3-hydroxy-3-phenacyl oxindole derivatives (II), dehydration of (II) gave 3-phenacylidene-2-indolinone derivatives (III).
Mohamed N. Ibrahim, Mohamed F. El-Messmary, Mohamed G. A. Elarfi   +2 more
doaj   +1 more source

Supramolecular Chiral Assembly of Open‐Shell Quinoids With Chiral Additives and Their Spin‐Dependent Transport in Magneto Field‐Effect Transistors

Small, Volume 22, Issue 38, 8 July 2026.
Open‐shell quinoids with intrinsic spins are assembled into chiral supramolecular structures via blending with chiral additives. Thermal annealing induces stable co‐crystallization, leading to a 30‐fold amplification of chirality (gabs = 1.23 × 10−2). Significantly, this study represents the first integration of spin‐possessing chiral assemblies into ...
Younghyo Kim, Jeongwoo Beak, Yunseul Kim, Seungrae Cho, Byungho Park, Kyoungtae Hwang, Kihyeun Kim, David H. Waldeck, Minwoo Lee, Taesun Yun, Chang‐Lyoul Lee, Dong‐Yu Kim   +11 more
wiley   +1 more source

Innovating Electrosynthesis From Metal Electrodeposition to Organic Chemistry: Deep Eutectic Solvents as Efficient and Sustainable Media

ChemSusChem, Volume 19, Issue 11, 15 June 2026.
This review analyzes deep eutectic solvents (DESs) as efficient media for both organic and inorganic electrosynthesis. The improvements in terms of synthetic opportunities and sustainability are discussed, by exploring the multiple roles of DESs as solvents, electrolytes, and promoters, enabling effective and selective electrosynthesis under mild and ...
Cristiana Margarita, Stefano Nejrotti, Alejandro Leal‐Duaso, Marta Feroci, Alessandra Sanson, Claudia Barolo, Matteo Bonomo   +6 more
wiley   +1 more source

Syntheses and Pharmacological Activities of Isatin Derivatives

Journal of Drug Delivery and Therapeutics, 2019
Twenty derivatives of isatin (1H-indole-2, 3-Dione) were synthesized by the schematic route as per as scheme. These were further characterized by spectroscopic analysis. All the novel synthesized derivatives of isatin were screened for their antimicrobial activity against Gram-positive bacteria: Staphylococcus aureus, Bacillus subtilis, Streptococcus ...
Asif Husain, Sushil Kumar, Neetu Sachan, Mayank Yadav   +3 more
openaire   +1 more source

Ultrasound‐Assisted Synthesis and Comprehensive Characterization of Nanosized VO(II), Fe(III), and Ru(III) Complexes: From Density Functional Theory/Nonlinear Optical Properties to Pharmaceutical Applications and Docking Insights

ChemistryOpen, Volume 15, Issue 6, June 2026.
Ultrasound‐assisted synthesis enabled the formation of ultrafine hydrazone‐based metal complexes with controlled nanostructures and enhanced stability. Density functional theory revealed optimized geometries and electronic properties. The nanosized complexes exhibited superior antimicrobial, anticancer, and antioxidant activities, supported by ...
R. A. El‐Kasaby, Eida S. Al‐Farraj, Senem Akkoc, Amal H. Alsehli, Maher Fathalla, Samir A. Abdel‐Latif, Mashael A. Alghamdi, Ahmed M. Abu‐Dief   +7 more
wiley   +1 more source

New bactericide derived from Isatin for treating oilfield reinjection water

Chemistry Central Journal, 2012
Isatin, an extract from Strobilanthes cusia (Nees) Kuntze, was the base for synthesizing derivatives that were screened for antibacterial activity against oilfield water-borne bacteria. The bacterial groups are sulfate reducing, iron and total.
Chen Gang, Su Hui-jun, Zhang Min, Huo Fang, Zhang Jie, Hao Xiao-jiang, Zhao Jing-rui   +6 more
doaj   +1 more source

A Series of Isatin-Hydrazones with Cytotoxic Activity and CDK2 Kinase Inhibitory Activity: A Potential Type II ATP Competitive Inhibitor

Molecules, 2020
Isatin derivatives potentially act on various biological targets. In this article, a series of novel isatin-hydrazones were synthesized in excellent yields.
Huda S. Al-Salem, Md Arifuzzaman, Hamad M. Alkahtani, Ashraf N. Abdalla, Iman S. Issa, Aljawharah Alqathama, Fatemah S. Albalawi, A. F. M. Motiur Rahman   +7 more
doaj   +1 more source

Phase‐Transfer‐Catalyzed Interrupted Barton–Zard Reaction Between Electron‐Deficient Indoles and Benzophenone‐Derived Isocyanides

European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
A cascade reaction under phase‐transfer conditions between 3‐nitro indoles and isocyanomethylene dibenzenes affords the construction of pyrrolo[3,4‐b]indole cores. Control experiments provide insight into moderate product yields and clarify why the reaction is not amenable to asymmetric induction. A cascade reaction enabling the construction of pyrrolo[
Ana Mikleušević, Ines Bašić, Mateja Matišić, Josip Rešetar, Matija Gredičak   +4 more
wiley   +1 more source

Synthesis of spiro[dihydropyridine-oxindoles] via three-component reaction of arylamine, isatin and cyclopentane-1,3-dione

Beilstein Journal of Organic Chemistry, 2013
A fast and convenient protocol for the synthesis of novel spiro[dihydropyridine-oxindole] derivatives in satisfactory yields was developed by the three-component reactions of arylamine, isatin and cyclopentane-1,3-dione in acetic acid at room temperature.
Yan Sun, Jing Sun, Chao-Guo Yan
doaj   +1 more source

Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
In this paper, a new series of isatin-sulphonamide based derivatives were designed, synthesised and evaluated as caspase inhibitors. The compounds containing 1-(pyrrolidinyl)sulphonyl and 2-(phenoxymethyl)pyrrolidin-1-yl)sulphonyl substitution at C5 ...
Loghman Firoozpour, Lixin Gao, Setareh Moghimi, Parvin Pasalar, Jamshid Davoodi, Ming-Wei Wang, Zahra Rezaei, Armin Dadgar, Hoda Yahyavi, Massoud Amanlou, Alireza Foroumadi   +10 more
doaj   +1 more source