Results 61 to 70 of about 660,493 (200)

Synthesis of spiro[dihydropyridine-oxindoles] via three-component reaction of arylamine, isatin and cyclopentane-1,3-dione

Beilstein Journal of Organic Chemistry, 2013
A fast and convenient protocol for the synthesis of novel spiro[dihydropyridine-oxindole] derivatives in satisfactory yields was developed by the three-component reactions of arylamine, isatin and cyclopentane-1,3-dione in acetic acid at room temperature.
Yan Sun, Jing Sun, Chao-Guo Yan
doaj   +1 more source

Synthesis and therapeutic evaluation of isatin-linked pyrazole motif derivatives

Multi-target drugs possess significant therapeutic potential for the therapy of complex diseases and drug-resistant conditions. Based on this fact, isatin-pyrazole derivatives, namely, 5-substituted isatin-pyrazole derivatives 7a-d and N-alkyl isatin ...
Hamad M. Alkahtani, Mashooq A. Bhat, Hazem A. Ghabbour, Ahmed M. Naglah, Mohamed A. Al-Omar, Ashraf S. Hassan, Abdulrahman A. Almehizia, Wael M. Aboulthana   +7 more
core   +1 more source

Defects Induced Instability of Perovskite Solar Cells

Advanced Energy and Sustainability Research, Volume 7, Issue 9, September 2026.
Defect passivation and grain‐size engineering in perovskite films are achieved through precursor additives, antisolvent additives, interfacial modification, light treatment, surface polishing, and temperature treatment. The synergistic effects suppress defect states and enhance film quality, providing insights into effective strategies for improving ...
Davoud Dastan, Fariba Tajabadi, Mohammad Sajedi Alvar, Mustafa Kareem, Amirhossein Rahimi, Mahboubeh Hadadian, Mohammad Hatamvand, Zhicheng Shi, Yingxin Chen, Lin Tao, Antonio Abate, Xi‐Tao Yin, Hanieh Helli, Mohammad Khaja Nazeeruddin   +13 more
wiley   +1 more source

New bactericide derived from Isatin for treating oilfield reinjection water

Chemistry Central Journal, 2012
Isatin, an extract from Strobilanthes cusia (Nees) Kuntze, was the base for synthesizing derivatives that were screened for antibacterial activity against oilfield water-borne bacteria. The bacterial groups are sulfate reducing, iron and total.
Chen Gang, Su Hui-jun, Zhang Min, Huo Fang, Zhang Jie, Hao Xiao-jiang, Zhao Jing-rui   +6 more
doaj   +1 more source

Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
In this paper, a new series of isatin-sulphonamide based derivatives were designed, synthesised and evaluated as caspase inhibitors. The compounds containing 1-(pyrrolidinyl)sulphonyl and 2-(phenoxymethyl)pyrrolidin-1-yl)sulphonyl substitution at C5 ...
Loghman Firoozpour, Lixin Gao, Setareh Moghimi, Parvin Pasalar, Jamshid Davoodi, Ming-Wei Wang, Zahra Rezaei, Armin Dadgar, Hoda Yahyavi, Massoud Amanlou, Alireza Foroumadi   +10 more
doaj   +1 more source

Computational analysis of 3-monosubstituted isatin derivatives for physicochemical properties and drug-likeness [PDF]

Isatin and its derivatives have garnered significant interest in medicinal chemistry due to their diverse pharmacological activities, including anticancer, antiviral, and antimicrobial effects.
Iliev, Ivelin; Medical University of Varna, Mihalev, Kaloyan; Medical University of Varna, Georgieva, Svetlana; Medical University of Varna   +2 more
core   +7 more sources

Overview of Photochemical Reactions for the Synthesis of Aza and Oxa‐Spirocyclic Compounds Under Visible Light Irradiation

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review presents the visible‐light‐mediated photochemical reaction for the synthesis of aza, oxa, and aza–oxa spirocyclic compounds via photoinduced electron transfer (PET), hydrogen atom transfer (HAT), single‐electron transfer (SET), or energy transfer (EnT) pathways.
Annu Bhardwaj, Shivangi Jaiswal, Khushboo Bhardwaj, Swapnil Sharma, Jaya Dwivedi   +4 more
wiley   +1 more source

A Series of Isatin-Hydrazones with Cytotoxic Activity and CDK2 Kinase Inhibitory Activity: A Potential Type II ATP Competitive Inhibitor

Molecules, 2020
Isatin derivatives potentially act on various biological targets. In this article, a series of novel isatin-hydrazones were synthesized in excellent yields.
Huda S. Al-Salem, Md Arifuzzaman, Hamad M. Alkahtani, Ashraf N. Abdalla, Iman S. Issa, Aljawharah Alqathama, Fatemah S. Albalawi, A. F. M. Motiur Rahman   +7 more
doaj   +1 more source

Synthesis Characterization, Biological Evaluation of Acetyl Substituted Heterocyclic Isatin Derivatives [PDF]

Isatin-1H-Indole-2,3-dione and its derivatives are group of indole derivatives that contain one nitrogen at the first position and two ketone groups at second and third position and is able to involve in electrophilic and nucleophilic substitution ...
Kadapal Gopal, D. Radha, Pyata Rohini, Dasari Pavithra, A. Kruthika, Kuruva Janardhan
core   +1 more source

Computational, In Vitro, and In Vivo Evaluation of Benzimidazole–Pyrazole Hybrid Scaffolds as Multi‐Target Anti‐Ulcer Agents

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The hybrid pharmacophore approach involves the combination of benzimidazole‐pyrazole moieties to form multi‐functional anti‐ulcer compounds. Molecular modeling and biological evaluations show significant proton pump inhibition, anti‐inflammatory action, antioxidant property, and remarkable prevention of gastric ulcers.
Hafiz Aamir Ali Kharl, Abdul Malik, Humaira Nadeem, Mohammad Shamsul Ola, Sara Aiman, Arif Ullah Khan, Muhammad Akmal Farooq, Humaira Muzaffar, Syed Muzzammil Masaud   +8 more
wiley   +1 more source