Results 71 to 80 of about 660,493 (200)

Synthesis of new functionalized thiazolo pyridine-fused and thiazolo pyridopyrimidine-fused spirooxindoles via one-pot reactions

Heliyon, 2020
A sequential multi-component reaction of the nitroketene dithioacetals, cysteamine hydrochloride, isatin and different CH-acids is described. This efficient method provides new functionalized thiazolo pyridine-fused spirooxindoles and thiazolo ...
Shima Nasri, Mohammad Bayat, Hassan Vasheghani Farahani, Solmaz Karami   +3 more
doaj   +1 more source

Therapeutic Potential of Alkanna tinctoria Root in Ameliorating Obesity‐Associated Hepatic, Adipose, and Reproductive Dysfunctions in Diet‐Induced Obese Zebrafish

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Obesity is a worldwide metabolic condition linked to various health problems such as non‐alcoholic fatty liver disease (NAFLD) and reproductive disorders. Anti‐obesity medications currently available on the market exhibit severe adverse effects, which leads to the exploration of safer natural alternatives. Alkanna tinctoria (L.) Tausch is well‐
Samriti Sharma, Deepika Choudhary, Anupam Kaur, Pooja Chadha   +3 more
wiley   +1 more source

Imide and isatin derivatives as γ-lactam mimics of β-lactamantibiotics

, 2002
Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the β-lactam antibiotics and their chemical and biological reactivity determined.
Hadfield, Peter S., Page, Michael I., Galt, Ronald H.B., Casey, Lorraine A., Vilanova, Bartholomew   +4 more
core   +3 more sources

Anti-Tubercular Activity of Isatin Derivatives

International Journal of Research in Pharmaceutical Sciences, 2010
Tuberculosis (TB) remains among the world’s great public health challenges. Worldwide resurgence of TB is due to two major problems: the acquired immunodeficiency syndrome (AIDS) epidemic, which started in the mid-1980s, and the outbreak of multidrug ...
Tarek Aboul-Fadl, Fayzah A. S. Bin-Jubair   +1 more
doaj  

Enantioselective Alkynylation of Isatin Derivatives Using a Chiral Phase-Transfer/Transition-Metal Hybrid Catalyst System

, 2019
An enantioselective alkynylation of isatin derivatives can be realized by using a hybrid catalyst system consisting of chiral phase-transfer catalyst and transition-metal catalyst.
Suva Paria (2618773), Keiji Maruoka, Keiji Maruoka (1433869), Hyo-Jun Lee (1478830), Suva Paria, Hyo-Jun Lee   +5 more
core   +1 more source

Synthesis, Characterization, and Antibacterial Activity of New Isatin Derivatives. [PDF]

Pharm Chem J, 2023
Nain S, Mathur G, Anthwal T, Sharma S, Paliwal S.   +4 more
europepmc   +1 more source

Bioactive and luminescent indole and isatin based gold(I) derivatives [PDF]

, 2019
A series of luminescent monometallic [AuL(PPh3)] (1-3) and bimetallic [Au2(μ-dppe)L2] (4, 6, 8) and [Au2(μ-dppp)L2] (5, 7, 9) complexes, where L is either 4-cyano-indole, isatin, or 5,7-dimethyl-isatin, and dppe and dppp are 1,2-bis(diphenylphosphino ...
Marzo, I., Gimeno, M. Concepción, Ospino, Isaura, Val-Campillo, C., Val-Campillo, Cynthia, Ospino, I., Fernández-Moreira, Vanesa, Marzo, Isabel, Laguna, Antonio, Herrera, Raquel P., Fernández-Moreira, V., Herrera, R.P., Laguna, A., Gimeno, M.C.   +13 more
core   +1 more source

Synthesis biological evaluation and molecular docking of isatin hybrids as anti-cancer and anti-microbial agents

Journal of Enzyme Inhibition and Medicinal Chemistry
Isatin, known as 1H-indole-2,3-dione, was originally recognised as a synthetic molecule until its discovery in the fruits of the cannonball tree, Couroupita guianensis.
Mohammad Altamimi, Saeed Ali Syed, Burak Tuzun, Mohammad Rashid Alhazani, Osamah Alnemer, Ahmed Bari   +5 more
doaj   +1 more source

Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors. [PDF]

J Enzyme Inhib Med Chem, 2023
Shaldam MA, Almahli H, Angeli A, Badi RM, Khaleel EF, Zain-Alabdeen AI, Elsayed ZM, Elkaeed EB, Salem R, Supuran CT, Eldehna WM, Tawfik HO.   +11 more
europepmc   +1 more source

Tackling Microbial Resistance with Isatin-Decorated Thiazole Derivatives: Design, Synthesis, and in vitro Evaluation of Antimicrobial and Antibiofilm Activity

Drug Design, Development and Therapy, 2022
Refaie M Kassab,1 Sami A Al-Hussain,2 Nooran S Elleboudy,3 Amgad Albohy,4 Magdi EA Zaki,2 Khaled AM Abouzid,5,6 Zeinab A Muhammad7 1Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt; 2Department of Chemistry, Faculty of ...
Kassab RM, Al-Hussain SA, Elleboudy NS, Albohy A, Zaki MEA, Abouzid KAM, Muhammad ZA   +6 more
doaj