Results 41 to 50 of about 4,322 (180)
Recent advances in isatin-derived hybrids: promising multifunctional agents for drug development [PDF]
Isatin-based hybrids have emerged as promising candidates in medicinal chemistry due to their broad biological activities and structural versatility. This review outlines recent developments (2020–2025) in the design of isatin hybrids targeting cancer ...
Aleksandar Dimkovski +2 more
doaj +1 more source
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis +2 more
wiley +1 more source
Solvatochromism of isatin based Schiff bases: An LSER and LFER study [PDF]
The derivatives of isatin have already been reported to show a variety of biological activities. However, there has been no report on solvatochromic effect of isatin derivatives so far, and that could be of interest to study and relate to their ...
Brkić Dominik R. +6 more
doaj +1 more source
Open‐shell quinoids with intrinsic spins are assembled into chiral supramolecular structures via blending with chiral additives. Thermal annealing induces stable co‐crystallization, leading to a 30‐fold amplification of chirality (gabs = 1.23 × 10−2). Significantly, this study represents the first integration of spin‐possessing chiral assemblies into ...
Younghyo Kim +11 more
wiley +1 more source
This study explores the design, synthesis and preliminary in silico screening of novel thiadiazole-isatin hybrid derivatives targeting diabetes mellitus.
Monika, Nishtha Shalmali, Priyanshu
doaj +1 more source
1-Tetradecylindoline-2,3-dione
In the title N-alkyl isatin, C22H33NO2, the isatin moiety is planar (r.m.s. deviation = 0.03 Å). The tetradecyl substituent has all torsion angles in an antiperiplanar conformation.
Khalil Mamari +3 more
doaj +1 more source
This review analyzes deep eutectic solvents (DESs) as efficient media for both organic and inorganic electrosynthesis. The improvements in terms of synthetic opportunities and sustainability are discussed, by exploring the multiple roles of DESs as solvents, electrolytes, and promoters, enabling effective and selective electrosynthesis under mild and ...
Cristiana Margarita +6 more
wiley +1 more source
Synthesis and Preliminary Antimicrobial Analysis of Isatin–Ferrocene and Isatin–Ferrocenyl Chalcone Conjugates [PDF]
In this study, we outline the synthesis of isatin-ferrocenyl chalcone and 1H-1,2,3-triazole-tethered isatin-ferrocene conjugates along with their antimicrobial evaluation against the human mucosal pathogen Trichomonas vaginalis. The introduction of a triazole ring among the synthesized conjugates improved the activity profiles with most of the ...
Amandeep Singh +10 more
openaire +3 more sources
A cascade reaction under phase‐transfer conditions between 3‐nitro indoles and isocyanomethylene dibenzenes affords the construction of pyrrolo[3,4‐b]indole cores. Control experiments provide insight into moderate product yields and clarify why the reaction is not amenable to asymmetric induction. A cascade reaction enabling the construction of pyrrolo[
Ana Mikleušević +4 more
wiley +1 more source

