Results 101 to 110 of about 7,251 (220)

Biological activities of isatin and its derivatives

, 2005
Izatin je endogeni spoj prisutan u organizmu čovjeka koji posjeduje niz farmakoloških učinaka. Izatin djeluje kao antioksidans, sedativ i antikonvulziv. In vitro je snažni antagonist na receptorima za natrijeve ione u atriju.
MAYANK JYOTI, SIVAKUMAR SMITHA, SRIDHAR, SESHAIAH KRISHNAN, SURENDRA NATH PANDEYA, PANDEYA, SURENDRA NATH, SESHAIAH KRISHNAN SRIDHAR, SMITHA, SIVAKUMAR, JYOTI, MAYANK   +7 more
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A neuroprotective dose of isatin causes multilevel changes involving the brain proteome: Prospects for further research

, 2021
Isatin (indole-2,3-dione) is an endogenous regulator, exhibiting a wide range of biological and pharmacological activities. At doses of 100 mg/kg and above, isatin is neuroprotective in different experimental models of neurodegeneration.
Medvedev A.
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Hemodynamic effon ects of isatin on isolated perfused heart

, 2014
Yüksek Lisans Teziİsatin vücut sıvılarında bulunan, natriüretik peptid antagonisti olduğu bilinen endojen bir indoldür. Bu çalışmada isatinin izole sıçan kalbindeki hemodinamik etkisi ve isatin uygulanmasına bağlı siklik guanozin monofosfat ...
Guksu, Zuhal
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A Survey of Isatin Hybrids and their Biological Properties

Molecular Diversity
The emergence of diverse infections worldwide, which is a serious global threat to human existence, necessitate the urgent development of novel therapeutic candidates that can combat these diseases with efficacy. Isatin, a secondary metabolite from tryptophan is considered a privileged scaffold and favorable pharmacophore with a unique structural ...
Vanessa Asoh Shu, Donatus Bekindaka Eni, Fidele Ntie-Kang   +2 more
openaire   +2 more sources

Mutagenicity and genotoxicity of isatin in mammalian cells in vivo

, 2011
Isatin (1H-indole-2,3-dione) is a synthetically versatile substrate used for the synthesis of heterocyclic compounds and as a raw material for drug synthesis.
Tamara Regina Calvo, Juliana Mara Serpeloni, Calvo, Tamara Regina [UNESP], Candido-Bacani, Priscila de Matos, Vilegas, Wagner, Varanda, Eliana Aparecida [UNESP], Wagner Vilegas, Serpeloni, Juliana Mara, Varanda, Eliana Aparecida, Priscila de Matos Cândido-Bacani, Calvo, Tamara Regina, Mariana Bisarro dos Reis, Eliana Aparecida Varanda, dos Reis, Mariana Bisarro, Ilce Mara de Syllos Cólus, de Syllos Colus, Ilce Mara, Vilegas, Wagner [UNESP]   +16 more
core   +1 more source

REAKSI ISATIN DENGAN 4-BROMOANILINA MAUPUN 3-BROMOANILINA

, 2014
Reaksi isatin dengan 2,5-dimetoksianilina dengan perbandingan 1:1 telah dikaji guna memperoleh 3-(2,5- dimetoksifenilimino)-1,3-dihidroindol-2-on, tapi yang diperoleh adalah 3,3-bis(4-amino-2,5-dimetoksifenil)-1,3-dihidroindol-2-on sehingga dilakukan
SAGITA, DEVIN ARI
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Synthesis and Supramolecular Organization of 5-(4-Alkylphenyl)isatin

, 2016
The synthesis of a homologous series of 5-(4-alkylphenyl)isatin derivatives, as well as the crystal structure and DFT studies of the respective hexyl derivative are presented, constituting the first examples of a new family of supramolecular bilayer ...
Dirk Blunk (2179042), Jan H. Porada (2179044), Jörg Neudörfl (2179046)   +2 more
core   +1 more source

ELECTROLYTIC REDUCTION OF ISATIN AND ITS DERIVATIVES. II. : REDUCTION OF N-METHYL ISATIN

, 1951
N-methyl-isatin can be reduced by the same process as in the case of isatin only by controlling the conditions as follows: (1) It is reduced to N-methyl-dioxyindol with lead cathode suspended in 20% dilute sulphuric acid solution.
SAKURAI, Buhei, SAKURAI Buhei
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5-Acetamido-1-(methoxybenzyl) isatin inhibits tumor cell proliferation, migration, and angiogenesis

, 2019
Indole and its derivatives are widely distributed in both animals and plants. Among its array of biological activities, the anti-tumor activity of indole has garnered much attention.
Yufan Zhao, Hervé Galons, Fu, Ying, Yu, Peng, Cui, Shanshan, Peng Yu, Zhang, Qian, Liu, Fengxi, Jing Wang, Wang, Jing, Galons, Hervé, Zhao, Yufan, Yuou Teng, Ying Fu, Yuan Yuan, Shanshan Cui, Fengxi Liu, Yuan, Yuan, Qian Zhang, Teng, Yuou   +19 more
core   +1 more source

Efficient removal of Cr(VI) from aqueous solutions using graphene Oxide@Isatin-PVP composite: Synthesis, characterization, and adsorption studies

Chemistry of Inorganic Materials
Chromium (VI) is a highly toxic and persistent heavy metal ion often present in industrial effluent, presenting significant hazards to human health and the environment.
Chandrakant D. Ghugare, Nilesh V. Rathod, Jayshri S. Jadhao, Ankita Rao, Akash V. Kubade, Parikshit S. Thakare, Arun B. Patil   +6 more
doaj   +1 more source