Results 121 to 130 of about 4,322 (180)

<i>Operando</i> benchtop NMR study of ion transport through fluorine-free polymer membranes in a symmetric redox flow cell.

open access: yesJ Mater Chem A Mater
Silva Testa GA   +6 more
europepmc   +1 more source

Antinociceptive effect and mechanism of action of isatin, N-methyl isatin and oxopropyl isatin in mice

open access: yesLife Sciences, 2016
There has been growing interest in the synthesis of new derivatives from isatin, found in Isatis genus. Our objectives were to characterize the antinociceptive mechanism of action of isatin, N-methyl-isatin (MI) and N-methyl-3-(2-oxopropyl)-3-hydroxy-2-oxindole (MOI).Substances (0.1-10mg/kg, p.o.) were studied in chemical (paw licking induced by ...
Patricia Dias Fernandes   +1 more
exaly   +3 more sources
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A Review an Isatin, Isatin Derivatives and their Pharmacological Activity

Research Journal of Pharmacology and Pharmacodynamics, 2021
Isatin or 1H-indole-2, 3-dione is an indole derivative. Isatin is an important class of heterocyclic compounds. Recently, heterocyclic compounds analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The structure have offered a high value of diversity that is proven
S. Janet Beula   +3 more
openaire   +1 more source

Alkylation of isatins with trichloroacetimidates

Organic & Biomolecular Chemistry, 2022
N-Alkylation or O-alkylation of isatins can be achieved utilizing trichloroacetimidate electrophiles with the major product being controlled by solvent effects. These reactions provide access to N-alkyl isatins, versatile scaffolds which are often employed in synthesis.
Nilamber A. Mate   +3 more
openaire   +2 more sources

Isatin dimers and their biological activities

Archiv Der Pharmazie, 2020
AbstractDimerization is a promising strategy to develop novel drug candidates that could extend the biological spectrum, enhance the activity, overcome drug resistance, as well as improve pharmacological, pharmacokinetic, and physicochemical profiles.
Zhi Xu
exaly   +3 more sources

Synthesis of Isatin Derivatives.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
E. G. Mesropyan   +3 more
openaire   +1 more source

The photochemistry of isatin

Journal of Photochemistry, 1987
Abstract Isatin does not show fluorescence or phosphorescence under any conditions. After excitation it undergoes rapid intersystem crossing to the triplet state (τ = 340 ns in deaerated benzene). This triplet state is capable of hydrogen abstraction, yielding a product analogous to pinacol, isatide.
G. Haucke, B. Seidel, A. Graness
openaire   +1 more source

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