Results 121 to 130 of about 4,322 (180)
Synthesis of novel spiro[chromeno[2,3-d][1,3,4]thiadiazolo[3,2-a] pyrimidines via an isatin-based three-component reaction. [PDF]
Khalili M, Esmaeili AA.
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Tricyclic Isatin Derivatives as Anti-Inflammatory Compounds with High Kinase Binding Affinity. [PDF]
Uvarov AV +3 more
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There has been growing interest in the synthesis of new derivatives from isatin, found in Isatis genus. Our objectives were to characterize the antinociceptive mechanism of action of isatin, N-methyl-isatin (MI) and N-methyl-3-(2-oxopropyl)-3-hydroxy-2-oxindole (MOI).Substances (0.1-10mg/kg, p.o.) were studied in chemical (paw licking induced by ...
Patricia Dias Fernandes +1 more
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A Review an Isatin, Isatin Derivatives and their Pharmacological Activity
Research Journal of Pharmacology and Pharmacodynamics, 2021Isatin or 1H-indole-2, 3-dione is an indole derivative. Isatin is an important class of heterocyclic compounds. Recently, heterocyclic compounds analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The structure have offered a high value of diversity that is proven
S. Janet Beula +3 more
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Alkylation of isatins with trichloroacetimidates
Organic & Biomolecular Chemistry, 2022N-Alkylation or O-alkylation of isatins can be achieved utilizing trichloroacetimidate electrophiles with the major product being controlled by solvent effects. These reactions provide access to N-alkyl isatins, versatile scaffolds which are often employed in synthesis.
Nilamber A. Mate +3 more
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Isatin dimers and their biological activities
Archiv Der Pharmazie, 2020AbstractDimerization is a promising strategy to develop novel drug candidates that could extend the biological spectrum, enhance the activity, overcome drug resistance, as well as improve pharmacological, pharmacokinetic, and physicochemical profiles.
Zhi Xu
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Synthesis of Isatin Derivatives.
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
E. G. Mesropyan +3 more
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Journal of Photochemistry, 1987
Abstract Isatin does not show fluorescence or phosphorescence under any conditions. After excitation it undergoes rapid intersystem crossing to the triplet state (τ = 340 ns in deaerated benzene). This triplet state is capable of hydrogen abstraction, yielding a product analogous to pinacol, isatide.
G. Haucke, B. Seidel, A. Graness
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Abstract Isatin does not show fluorescence or phosphorescence under any conditions. After excitation it undergoes rapid intersystem crossing to the triplet state (τ = 340 ns in deaerated benzene). This triplet state is capable of hydrogen abstraction, yielding a product analogous to pinacol, isatide.
G. Haucke, B. Seidel, A. Graness
openaire +1 more source

