Results 141 to 150 of about 8,195 (166)

2-Oxoindoline-based hydroxamic acids: novel HDAC inhibitors with promising anticancer activity. [PDF]

RSC Adv
Huong TTL, Kim HK, Thai NA, Anh DP, Thao NTP, Ngan NP, Thang NQ, Kang DH, Kim HY, Kang JS, Anh DT, Tung TT, Han SB, Nam NH.   +13 more
europepmc   +1 more source

Synthesis of heterocycles based on azomethine ylides from α-amino acids (or amines) and carbonyl compounds. [PDF]

Beilstein J Org Chem
Berezhnaya EV, Ponyaev AI, Boitsov VM, Stepakov AV.   +3 more
europepmc   +1 more source

Synthesis, spectroscopic investigation, theoretical insights via DFT and biological assessment of some isatin-based metal complexes. [PDF]

Sci Rep
El-Gammal OA, El-Boraey HA, Tolan DA.
europepmc   +1 more source

Dual Targeting Strategies in Cancer: Carbonic Anhydrase IX Inhibitors Targeting EGFR or VEGFR-2. [PDF]

Molecules
Charissopoulos E, Pontiki E.
europepmc   +1 more source

Synthesis and multipurpose assessment of Cu(II) and Pd(II) Schiff base complexes as catalysts and antimicrobial agents. [PDF]

Sci Rep
Malav R, Ray S.
europepmc   +1 more source

Isatin, a monoamine oxidase inhibitor, sensitizes resistant breast cancer cells to tamoxifen <i>via</i> MAO-A/HIF1α/MMPs modulation. [PDF]

RSC Med Chem
Abdelwahed FM, Ibrahim MA, Sharaky M, Effat H.   +3 more
europepmc   +1 more source

Molecular iodine catalyzed C3-quaternization <i>via</i> oxidative dearomatization of indoles: direct access to 3,3-di(indolyl)indolin-2-ones. [PDF]

RSC Adv
Singh N, Kokatla HP, Naddi N, Inapanuri M.   +3 more
europepmc   +1 more source

Synthesis, antitumor evaluation, and <i>in silico</i> investigation of pyridine-based pyrimidotriazine and triazolopyrimidine derivatives as potential EGFR-targeted anticancer agents. [PDF]

RSC Adv
Ramadan SK, Abdelrahman AH, Hegazy MA, Labena A, Gomha SM, Zaki MEA, Azab ME.   +6 more
europepmc   +1 more source

Isatin: A Link Between Natriuretic Peptides and Monoamines?

Biochemical Pharmacology, 1996
Isatin is an endogenous indole with a distinctive distribution in brain and tissues. In the brain, the highest levels have been found in the hippocampus (0.1 μg/g), and an immunocytochemical stain has shown specific localization within particular cells ...
Vivette Glover, Alexei Medvedev, Angela Clow   +2 more
exaly   +2 more sources

Biochemical and Pharmacological Characterization of Isatin and Its Derivatives: From Structure to Activity

Pharmacological Reports, 2013
Isatin, 1H-indole-2,3-dione, is a heterocyclic compound of significant importance in medicinal chemistry. It is a synthetically versatile molecule, a precursor for a large number of pharmacologically active compounds.
Soheila Kashanian, Mohammad Mehdi Khodaei, Parvaneh Pakravan   +2 more
exaly   +2 more sources