Results 171 to 180 of about 9,186 (209)
Umpolung Activation of Bicyclobutanes via N-Heterocyclic Carbene Catalysis. [PDF]
Chang YC +5 more
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Carbon and Heteroatom Activation via N-Heterocyclic Carbene-Bound Dearomative Intermediates for Stereoselective Annulation Reactions. [PDF]
De Risi C +4 more
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Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel Coumarin-Triazole-Isatin Hybrids as Selective Butyrylcholinesterase Inhibitors. [PDF]
Dimkovski A +6 more
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Alkylation of isatins with trichloroacetimidates
Organic & Biomolecular Chemistry, 2022N-Alkylation or O-alkylation of isatins can be achieved utilizing trichloroacetimidate electrophiles with the major product being controlled by solvent effects. These reactions provide access to N-alkyl isatins, versatile scaffolds which are often employed in synthesis.
Nilamber A. Mate +3 more
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A Review an Isatin, Isatin Derivatives and their Pharmacological Activity
Research Journal of Pharmacology and Pharmacodynamics, 2021Isatin or 1H-indole-2, 3-dione is an indole derivative. Isatin is an important class of heterocyclic compounds. Recently, heterocyclic compounds analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The structure have offered a high value of diversity that is proven
S. Janet Beula +3 more
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Synthesis of Isatin Derivatives.
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
E. G. Mesropyan +3 more
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Isatin‐1,2,3‐triazole‐isatin Scaffolds and Their Antibacterial Activity
Journal of Heterocyclic Chemistry, 2019Twelve novel isatin‐1,2,3‐triazole‐isatin scaffolds 5a–l were designed, synthesized, and assessed for their in vitro antibacterial activity in this paper. The preliminary results showed that all dimers only endowed with weak antibacterial activity, which was less active than the reference ciprofloxacin.
Ruijing Cheng, Xinjia Yan, Zhi Xu
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Reductive 1,2-Arylation of Isatins
Organic Letters, 2022We report an intermolecular Ni-catalyzed reductive coupling of aryl iodides and isatins to form 3-hydroxyoxindoles. In contrast to common metal-mediated methods, sec-butanol is used as a mild stoichiometric reductant resulting in benign waste products.
Amrah Nasim +3 more
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Chemistry – An Asian Journal, 2020
AbstractA general method for the construction of trifluoromethylated 2‐quinolinones has been established herein by using a trifluoromethylative ring expansion of isatin with trifluorodiazoethane. The strategy provides a platform for the rapid synthesis of a wide range of substituted 3‐hydroxy‐4‐trifluoromethyl‐2‐quinolinones.
Muhammad Fahad Jamali +4 more
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AbstractA general method for the construction of trifluoromethylated 2‐quinolinones has been established herein by using a trifluoromethylative ring expansion of isatin with trifluorodiazoethane. The strategy provides a platform for the rapid synthesis of a wide range of substituted 3‐hydroxy‐4‐trifluoromethyl‐2‐quinolinones.
Muhammad Fahad Jamali +4 more
openaire +2 more sources

