Results 131 to 140 of about 3,007 (178)

A Review an Isatin, Isatin Derivatives and their Pharmacological Activity

Research Journal of Pharmacology and Pharmacodynamics, 2021
Isatin or 1H-indole-2, 3-dione is an indole derivative. Isatin is an important class of heterocyclic compounds. Recently, heterocyclic compounds analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The structure have offered a high value of diversity that is proven
S. Janet Beula, T. Rama Mohan Reddy, R. Suthakaran, Suneetha K.   +3 more
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Pharmacophore Modeling and 3D-QSAR Study of Indole and Isatin Derivatives as Antiamyloidogenic Agents Targeting Alzheimer’s Disease [PDF]

Molecules, 2020
Cosimo Damiano Altomare, Orazio Nicolotti, Alba Espargaró   +2 more
exaly   +2 more sources

Synthesis of Isatin Derivatives.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
E. G. Mesropyan, G. B. Ambartsumyan, A. A. Avetisyan, M. G. Sarkisyan   +3 more
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New isatin derivatives

Russian Journal of Organic Chemistry, 2009
The review compiles published data on the synthesis and biological action of new isatin derivatives containing in their composition additional oxygen, nitrogen, or sulfur heterocycles.
E. G. Mesropyan, A. A. Avetisyan
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New isatin derivatives with antioxidant activity

European Journal of Medicinal Chemistry, 2010
The reaction between isatin and 2,5-dimethoxyaniline is described. The main product was identified as 3,3-bis(4-amino-2,5-dimethoxyphenyl)-1,3-dihydroindol-2-one. The antioxidant activity of the compounds isolated was evaluated with two methods. Three published antitumor E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones entered the same tests to
ANDREANI, ALDO, BURNELLI, SILVIA, GRANAIOLA, MASSIMILIANO, LEONI, ALBERTO, LOCATELLI, ALESSANDRA, MORIGI, RITA, RAMBALDI, MIRELLA, VAROLI, LUCILLA, CREMONINI, MAURO ANDREA, PLACUCCI, GIUSEPPE, CERVELLATI, RINALDO, GRECO, EMANUELA   +11 more
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Synthesis of New Aromatic Isatin Derivatives

Russian Journal of Organic Chemistry, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
E. G. Mesropyan, G. B. Ambartsumyan, A. A. Avetisyan, M. G. Sargsyan, A. S. Galstyan   +4 more
openaire   +1 more source

Electrochemical characterization of isatin-thiosemicarbazone derivatives

Journal of Chemical Sciences, 2021
Herein, we have notably described the electrochemical behavior of four isatin-thiosemicarbazone derivatives. In this regard, cyclic voltammograms of isatin-3-thiosemicarbazone (ITSC), isatin-3-(N4-benzylthiosemicarbazone) (ITSC-Ph), 1-(5-nitro-2-oxoindolin-3-ylidene)thiosemicarbazide (NO2-ITSC) and 1-(5-nitro-2-oxoindolin-3-ylidene)-4 ...
Juliano da Rosa Justim, Lucas Martins Correa Bohs, Bianca Barreto Martins, Katlen Christian Tribuzy Bandeira, Ana Paula Lopes de Melo, Vanessa Carratu Gervini, Leandro Bresolin, Marcelo Godoi, Carlos Roberto de Menezes Peixoto   +8 more
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VASODILATORY ACTIVITY OF NOVEL CARBAMATE DERIVATIVES OF ISATIN

Clinical and Experimental Pharmacology and Physiology, 2008
SUMMARY Isatin (1H‐indole‐2,3 dione) is an endogenous compound that may act as a physiological regulator of muscle contraction by reducing cGMP production by inhibition of guanylyl cyclase (GC) activity. Intracellular cGMP levels can regulate the contractile response of smooth muscle.
Patricia A, Maroñas, Roberto T, Sudo, Marilza B, Corrêa, Angelo C, Pinto, Simon J, Garden, Margarete M, Trachez, Gisele, Zapata-Sudo   +6 more
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New isatin derivatives: synthesis and reactions

Synthetic Metals, 1990
Abstract The synthesis of new 5-substituted isatins with 2-thienyl, 3-thienyl, 2,2′-bithien-5-yl and phenyl substituents is described. The compounds were prepared via the palladium-catalysed cross-coupling reaction of 5-bromoisatin with 2-thiophene, 3-thiophene, 2,2′-bithien-5-yl and benzene boronic acids, respectively.
Francisco Martinez, Herbert Naarmann
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Synthesis of Isatin and 5-Bromoisatin Derivatives

Russian Journal of Organic Chemistry, 2001
New N-derivatives of isatin were synthesized by treating ethyl chloroacetate, N-(2-chloroethyl)morpholine, and 1,4-di(chloromethyl)benzene with isatin sodium salt. N-Derivatives of isatin and 5-bromoisatin were also prepared by Mannich reaction.
E. G. Mesropyan, G. B. Ambartsumyan, A. A. Avetisyan, M. G. Sarkisyan, G. S. Amazaspyan   +4 more
openaire   +1 more source