Results 151 to 160 of about 660,493 (200)

Isatin Halogen-Derivatives Redox Behaviour

Journal of Electroanalytical Chemistry, 2016
Abstract Isatin halogen-derivatives like other isatin derivatives have several pharmacoterapeutic applications, such as antibacterial, antitubercular, and anticancer activities. The electrochemical behaviour, at a glassy carbon electrode, of some mono- and di- fluoro, chloro, bromo and iodo isatin derivatives, by cyclic, square wave and differential ...
Isabel P G Fernandes, Ana Maria Oliveira-Brett, Bárbara V Silva   +2 more
exaly   +2 more sources

Micellar Effects on the Alkaline Hydrolysis of Isatin and Its Derivatives

Journal of Colloid and Interface Science, 2011
Herein we have investigated the hydrolysis of 1H-indol-2,3-dione (isatin, I) and its derivatives of different hydrophobicities, viz. N-dimethylaminomethyl indol-2,3-dione (II), N-morpholinomethyl indol-2,3-dione (III), N-pipridinomethyl indol-2,3-dione (IV), N-heptylaminomethyl indol-2,3-dione (V), N-dodecylaminomethyl indol-2,3-dione (VI), N ...
Hamad A Al-Lohedan, Mohd Sajid Ali, Zuheir A Issa   +2 more
exaly   +3 more sources

Biochemical and Pharmacological Characterization of Isatin and Its Derivatives: From Structure to Activity

Pharmacological Reports, 2013
Isatin, 1H-indole-2,3-dione, is a heterocyclic compound of significant importance in medicinal chemistry. It is a synthetically versatile molecule, a precursor for a large number of pharmacologically active compounds.
Soheila Kashanian, Mohammad Mehdi Khodaei, Parvaneh Pakravan   +2 more
exaly   +2 more sources

A Review an Isatin, Isatin Derivatives and their Pharmacological Activity

Research Journal of Pharmacology and Pharmacodynamics, 2021
Isatin or 1H-indole-2, 3-dione is an indole derivative. Isatin is an important class of heterocyclic compounds. Recently, heterocyclic compounds analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The structure have offered a high value of diversity that is proven
S. Janet Beula, T. Rama Mohan Reddy, R. Suthakaran, Suneetha K.   +3 more
openaire   +1 more source

Synthesis of Isatin Derivatives.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
E. G. Mesropyan, G. B. Ambartsumyan, A. A. Avetisyan, M. G. Sarkisyan   +3 more
openaire   +1 more source

New isatin derivatives with antioxidant activity

European Journal of Medicinal Chemistry, 2010
The reaction between isatin and 2,5-dimethoxyaniline is described. The main product was identified as 3,3-bis(4-amino-2,5-dimethoxyphenyl)-1,3-dihydroindol-2-one. The antioxidant activity of the compounds isolated was evaluated with two methods. Three published antitumor E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones entered the same tests to
ANDREANI, ALDO, BURNELLI, SILVIA, GRANAIOLA, MASSIMILIANO, LEONI, ALBERTO, LOCATELLI, ALESSANDRA, MORIGI, RITA, RAMBALDI, MIRELLA, VAROLI, LUCILLA, CREMONINI, MAURO ANDREA, PLACUCCI, GIUSEPPE, CERVELLATI, RINALDO, GRECO, EMANUELA   +11 more
openaire   +2 more sources

Synthesis of New Aromatic Isatin Derivatives

Russian Journal of Organic Chemistry, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
E. G. Mesropyan, G. B. Ambartsumyan, A. A. Avetisyan, M. G. Sargsyan, A. S. Galstyan   +4 more
openaire   +1 more source

Electrochemical characterization of isatin-thiosemicarbazone derivatives

Journal of Chemical Sciences, 2021
Herein, we have notably described the electrochemical behavior of four isatin-thiosemicarbazone derivatives. In this regard, cyclic voltammograms of isatin-3-thiosemicarbazone (ITSC), isatin-3-(N4-benzylthiosemicarbazone) (ITSC-Ph), 1-(5-nitro-2-oxoindolin-3-ylidene)thiosemicarbazide (NO2-ITSC) and 1-(5-nitro-2-oxoindolin-3-ylidene)-4 ...
Juliano da Rosa Justim, Lucas Martins Correa Bohs, Bianca Barreto Martins, Katlen Christian Tribuzy Bandeira, Ana Paula Lopes de Melo, Vanessa Carratu Gervini, Leandro Bresolin, Marcelo Godoi, Carlos Roberto de Menezes Peixoto   +8 more
openaire   +1 more source

VASODILATORY ACTIVITY OF NOVEL CARBAMATE DERIVATIVES OF ISATIN

Clinical and Experimental Pharmacology and Physiology, 2008
SUMMARY Isatin (1H‐indole‐2,3 dione) is an endogenous compound that may act as a physiological regulator of muscle contraction by reducing cGMP production by inhibition of guanylyl cyclase (GC) activity. Intracellular cGMP levels can regulate the contractile response of smooth muscle.
Patricia A, Maroñas, Roberto T, Sudo, Marilza B, Corrêa, Angelo C, Pinto, Simon J, Garden, Margarete M, Trachez, Gisele, Zapata-Sudo   +6 more
openaire   +2 more sources

New isatin derivatives: synthesis and reactions

Synthetic Metals, 1990
Abstract The synthesis of new 5-substituted isatins with 2-thienyl, 3-thienyl, 2,2′-bithien-5-yl and phenyl substituents is described. The compounds were prepared via the palladium-catalysed cross-coupling reaction of 5-bromoisatin with 2-thiophene, 3-thiophene, 2,2′-bithien-5-yl and benzene boronic acids, respectively.
Francisco Martinez, Herbert Naarmann
openaire   +1 more source