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Special Issue "Biosynthesis and Application of Natural Compound". [PDF]

Int J Mol Sci
Luzina OA, Volcho KP.
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Isatin derivatives and their anti-bacterial activities

European Journal of Medicinal Chemistry, 2019
Bacterial infections are account for the majority of hospital-acquired and community-acquired infections. The emergency and widespread of drug-resistant pathogens has further worsened the situation. In recent years, various isatin derivatives have been screened for their anti-bacterial activities, and some of them demonstrated promising in vitro and in 
Hua Guo
exaly   +4 more sources

Isatin Derivatives: A Frontier in Antimicrobial Agents

Letters in Organic Chemistry, 2023
Abstract: Microbial infection is one of the major concerns for human health in the modern era. Condition is further worsening due to the development of resistance by the microbe against the available drugs. This problem can be overcome by synthesizing novel antimicrobial agents. Isatin is a promising moiety possessing antimicrobial activity.
Charanjit Kaur, Gurvinder Singh
exaly   +3 more sources

A Review an Isatin, Isatin Derivatives and their Pharmacological Activity

Research Journal of Pharmacology and Pharmacodynamics, 2021
Isatin or 1H-indole-2, 3-dione is an indole derivative. Isatin is an important class of heterocyclic compounds. Recently, heterocyclic compounds analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The structure have offered a high value of diversity that is proven
S. Janet Beula, T. Rama Mohan Reddy, R. Suthakaran, Suneetha K.   +3 more
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Isatin nitro-derivatives redox behaviour

Journal of Electroanalytical Chemistry, 2013
Abstract Isatin derivatives possess a broad pharmacological profile and clinical applications, and the electrochemical behaviour of isatin-3-hydrazone, 7-methylisatin-3-hydrazone, isatin-3-semicarbazone, isatin-3-thiosemicarbazone, 5-bromoisatin-3-thiosemicarbazone and 5-nitroisatin, at a glassy carbon electrode, using cyclic, square-wave and ...
Severino Carlos B Oliveira, Isabel P G Fernandes, Barbara V Silva   +2 more
exaly   +2 more sources

Isatin halogen-derivatives redox behaviour

Journal of Electroanalytical Chemistry, 2016
Abstract Isatin halogen-derivatives like other isatin derivatives have several pharmacoterapeutic applications, such as antibacterial, antitubercular, and anticancer activities. The electrochemical behaviour, at a glassy carbon electrode, of some mono- and di- fluoro, chloro, bromo and iodo isatin derivatives, by cyclic, square wave and differential ...
Isabel P G Fernandes, Barbara V Silva, Severino Carlos B Oliveira   +2 more
exaly   +2 more sources

Analysis of DNA protection, interaction and antimicrobial activity of isatin derivatives

International Journal of Biological Macromolecules, 2019
Isatin, thiosemicarbazone and their derivatives have been widely used in biological applications such as antimicrobial, antiviral and anticancer therapies.
Mehmet Cengiz Baloǧlu, Aysenur Aygün, Yasemin Çelik Altunoglu   +2 more
exaly   +2 more sources

Micellar effects on the alkaline hydrolysis of isatin and its derivatives

Journal of Colloid and Interface Science, 2011
Herein we have investigated the hydrolysis of 1H-indol-2,3-dione (isatin, I) and its derivatives of different hydrophobicities, viz. N-dimethylaminomethyl indol-2,3-dione (II), N-morpholinomethyl indol-2,3-dione (III), N-pipridinomethyl indol-2,3-dione (IV), N-heptylaminomethyl indol-2,3-dione (V), N-dodecylaminomethyl indol-2,3-dione (VI), N ...
Mohd Sajid Ali, Hamad A Al-Lohedan, Zuheir A Issa   +2 more
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New antileishmanial quinoline linked isatin derivatives targeting DHFR-TS and PTR1: Design, synthesis, and molecular modeling studies.

European journal of medicinal chemistry, 2022
In a search for new drug candidates for one of the neglected tropical diseases, leishmaniasis, twenty quinoline-isatin hybrids were synthesized and tested for their in vitro antileishmanial activity against Leishmaniamajor strain.
Ahmed Sabt, Wagdy M. Eldehna, Tamer M. Ibrahim, A. Bekhit, Rasha Z. Batran   +4 more
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Synthesis of Isatin Derivatives.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
E. G. Mesropyan, G. B. Ambartsumyan, A. A. Avetisyan, M. G. Sarkisyan   +3 more
openaire   +1 more source