Results 51 to 60 of about 1,179 (184)

Molecular Iodine-Catalyzed Synthesis of 3,3-Disubstituted Isatins: Total Synthesis of Indole Alkaloid, 3,3-Dimethoxy-2-oxindole

Chemistry
3,3-Dialkoxy-2-oxindoles are prevalent in natural products and exhibit unique biological activities. Among them, acyclic alkoxy analogues show instability in acidic conditions, making access to acyclic isatin ketals highly challenging.
Keisuke Tokushige, Shota Asai, Takumi Abe   +2 more
doaj   +1 more source

5-Bromo-1H-indole-2,3-dione

IUCrData, 2016
The title compound, C8H4BrNO2, has a single, almost planar, planar molecule in the asymmetric unit, with the non-H atoms having a mean deviation from planarity of 0.024 Å.
Sita Gurung, James A. Golen, David R. Manke   +2 more
doaj   +1 more source

Synthesis and Preliminary Antimicrobial Analysis of Isatin–Ferrocene and Isatin–Ferrocenyl Chalcone Conjugates [PDF]

ACS Omega, 2018
In this study, we outline the synthesis of isatin-ferrocenyl chalcone and 1H-1,2,3-triazole-tethered isatin-ferrocene conjugates along with their antimicrobial evaluation against the human mucosal pathogen Trichomonas vaginalis. The introduction of a triazole ring among the synthesized conjugates improved the activity profiles with most of the ...
Amandeep Singh, Grant Fong, Jenny Liu, Yun-Hsuan Wu, Kevin Chang, William Park, Jihwan Kim, Christina Tam, Luisa W. Cheng, Kirkwood M. Land, Vipan Kumar   +10 more
openaire   +3 more sources

Mesityl‐Substituted Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxalines: Synthesis, Functionalization, Photophysical, and Electrochemical Properties

European Journal of Organic Chemistry, Volume 29, Issue 26, 13 July 2026.
Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxaline with a mesityl group as a solubilizing group was synthesized. By synthesizing derivatives in which various functional groups were introduced into two electronically distinct sites, the pyrrole nitrogen atom and the azulene five‐membered ring, we were able to reveal that the photophysical and electrochemical ...
Ryuta Sekiguchi, Hiroki Mizuno, Ikumi Uchiyama, Souta Yuruka, Atsuya Shimizu, Taku Shoji, Shunji Ito   +6 more
wiley   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

Supramolecular Chiral Assembly of Open‐Shell Quinoids With Chiral Additives and Their Spin‐Dependent Transport in Magneto Field‐Effect Transistors

Small, Volume 22, Issue 38, 8 July 2026.
Open‐shell quinoids with intrinsic spins are assembled into chiral supramolecular structures via blending with chiral additives. Thermal annealing induces stable co‐crystallization, leading to a 30‐fold amplification of chirality (gabs = 1.23 × 10−2). Significantly, this study represents the first integration of spin‐possessing chiral assemblies into ...
Younghyo Kim, Jeongwoo Beak, Yunseul Kim, Seungrae Cho, Byungho Park, Kyoungtae Hwang, Kihyeun Kim, David H. Waldeck, Minwoo Lee, Taesun Yun, Chang‐Lyoul Lee, Dong‐Yu Kim   +11 more
wiley   +1 more source

Innovating Electrosynthesis From Metal Electrodeposition to Organic Chemistry: Deep Eutectic Solvents as Efficient and Sustainable Media

ChemSusChem, Volume 19, Issue 11, 15 June 2026.
This review analyzes deep eutectic solvents (DESs) as efficient media for both organic and inorganic electrosynthesis. The improvements in terms of synthetic opportunities and sustainability are discussed, by exploring the multiple roles of DESs as solvents, electrolytes, and promoters, enabling effective and selective electrosynthesis under mild and ...
Cristiana Margarita, Stefano Nejrotti, Alejandro Leal‐Duaso, Marta Feroci, Alessandra Sanson, Claudia Barolo, Matteo Bonomo   +6 more
wiley   +1 more source

Ultrasound‐Assisted Synthesis and Comprehensive Characterization of Nanosized VO(II), Fe(III), and Ru(III) Complexes: From Density Functional Theory/Nonlinear Optical Properties to Pharmaceutical Applications and Docking Insights

ChemistryOpen, Volume 15, Issue 6, June 2026.
Ultrasound‐assisted synthesis enabled the formation of ultrafine hydrazone‐based metal complexes with controlled nanostructures and enhanced stability. Density functional theory revealed optimized geometries and electronic properties. The nanosized complexes exhibited superior antimicrobial, anticancer, and antioxidant activities, supported by ...
R. A. El‐Kasaby, Eida S. Al‐Farraj, Senem Akkoc, Amal H. Alsehli, Maher Fathalla, Samir A. Abdel‐Latif, Mashael A. Alghamdi, Ahmed M. Abu‐Dief   +7 more
wiley   +1 more source

Metal-Dependent Umpolung Reactivity of Carbenes Derived from Cyclopropenes

iScience, 2019
Summary: Metal carbenes, divalent carbon species, are versatile intermediates that enable novel synthetic pathways. These species exhibit either electrophilic or nucleophilic character, depending on the carbene and metal fragments.
Dan Zhang, Zhenghui Kang, Junwen Liu, Wenhao Hu   +3 more
doaj   +1 more source

Phase‐Transfer‐Catalyzed Interrupted Barton–Zard Reaction Between Electron‐Deficient Indoles and Benzophenone‐Derived Isocyanides

European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
A cascade reaction under phase‐transfer conditions between 3‐nitro indoles and isocyanomethylene dibenzenes affords the construction of pyrrolo[3,4‐b]indole cores. Control experiments provide insight into moderate product yields and clarify why the reaction is not amenable to asymmetric induction. A cascade reaction enabling the construction of pyrrolo[
Ana Mikleušević, Ines Bašić, Mateja Matišić, Josip Rešetar, Matija Gredičak   +4 more
wiley   +1 more source