Results 41 to 50 of about 240,454 (314)

Platelet Activating Factor Synthesis and Metabolism in Intestinal Ischaemia-Reperfusion Injury

open access: yesMediators of Inflammation, 1994
The object of this study was to characterize the synthesis and metabolism of platelet activating factor (PAF) by intestinal mucosa subjected to ischaemia–reperfusion injury.
M. J. Mangino   +3 more
doaj   +1 more source

The Diagnostic Significance of the Holter Monitoring in the Evaluation of Palpitation [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Purpose: To determine the diagnostic yield of the 24-hour Holter monitoring in the patients who were evaluated for palpitations. Methods: A prospective, single-centre study was performed to evaluate the diagnostic yield of the Holter monitoring.
Badri Paudel, Klara Paudel
doaj   +1 more source

Choroidal vascular ischaemia [PDF]

open access: yesEye, 1991
The term 'choroidal vascular ischaemia' refers to all the choroido-retinal changes which follow an acute or chronic circulatory disorder in the arterial capillary or venous network of the choroid. However, different clinical syndromes can be observed according to the type of vessel which is occluded, the origin and rate of development of the process ...
openaire   +2 more sources

Antegrade coeliac axis reconstruction for Chronic Mesenteric Ischaemia : a case series [PDF]

open access: yes, 2009
The management of chronic mesenteric ischaemia remains a compelling challenge for many vascular surgeons. Over the past four decades, several reports have demonstrated encouraging results following revascularisation of the splanchnic arteries.
Tait, William F.   +3 more
core  

Prevention of serious vascular events by aspirin amongst patients with peripheral arterial disease : randomized, double-blind trial

open access: yes, 2007
OBJECTIVE: To assess the prophylactic efficacy of aspirin and a high-dose antioxidant vitamin combination in patients with peripheral arterial disease (PAD) in terms of reduction of the risk of a first vascular event (myocardial infarction, stroke ...
M. Catalano   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Monitoring the skin NADH changes during ischaemia and reperfusion in humans

open access: yesJournal of Medical Science, 2020
Nicotinamide adenine dinucleotide (NADH/NAD+) is involved in many important biochemical reactions in human metabolism, including participation in energy production by mitochondria.
Jan Niziński   +4 more
doaj   +1 more source

Development and validation of a quantitative electron microscopy score to assess acute cellular stress in the human exocrine pancreas

open access: yesThe Journal of Pathology: Clinical Research, 2021
The pancreas is particularly sensitive to acute cellular stress, but this has been difficult to evaluate using light microscopy. Pancreatic ischaemia associated with deceased organ donation negatively impacts whole‐organ and isolated‐islet ...
Nicole Kattner   +13 more
doaj   +1 more source

Ischaemia-modified albumin: Clinical utility and pitfalls in measurement

open access: yes, 2008
Ischaemia occurs when there is a supply demand mismatch in cardiac blood flow. In unstable angina, this occurs due to partial or total occlusion of a coronary artery due to plaque rupture.
Collinson, P.O., Gaze, D.C.
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

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