Results 211 to 220 of about 170,400 (293)

Attenuation of renal ischemia/reperfusion injury by oleanolic acid preconditioning via its antioxidant, anti-inflammatory, and anti-apoptotic activities

, 2016
Chengmei Long, Jinran Yang, Hua Yang, Xinchang Li, Gongxian Wang   +4 more
openalex   +2 more sources

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

VAMP4 in hypoxic adipose stem cell exosomes alleviates ischemia-reperfusion injury. [PDF]

Cell Mol Life Sci
Wang Y, Yu S, Wang X, Jin R, Liu F, Yang J.   +5 more
europepmc   +1 more source

Effects of sodium–glucose co‐transporter inhibitors on individual clinical endpoints and quality of life

ESC Heart Failure, Volume 12, Issue 2, Page 1271-1282, April 2025.
Effects of SGLTi on Individual Clinical Endpoints and Quality‐of‐Life: outcome from randomized data. Abstract Aims Sodium–glucose co‐transporter inhibitors (SGLTis) have cardiovascular protective effects. We aimed to assess the effects of SGLTis on individual hard clinical endpoints and quality of life (QoL) in patients with cardiovascular risk factors.
Jia Liao, Yang Chen, Zhiyu Ling, Helmut Pürerfellner, Martin Martinek, Michael Derndorfer, Johannes Niel, Ramin Ebrahimi, Matthias Heukäufer, Sarah Janschel, Davide Di Vece, Klaus Empen, Astrid Hummel, Bishwas Chamling, Piotr Futyma, Fahim Ebrahimi, Márcio G. Kiuchi, Shaowen Liu, Yuehui Yin, Alexandra Schratter, Willem‐Jan Acou, Philipp Sommer, Boris Schmidt, Julian K. R. Chun, Christian Meyer, Marcus Dörr, Christian Templin, Shaojie Chen   +27 more
wiley   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

NEDD4 suppresses ferroptosis in lung ischemia-reperfusion injury by ubiquitinating and degrading SLC1A5. [PDF]

Sci Rep
Li J, Meng F, Qian X, Chen S.
europepmc   +1 more source

A2A Adenosine Receptor Agonists With Last‐Step Enzymatic 18F‐Labelling Potential (Fluorinase) for Positron Emission Tomography (PET)

European Journal of Organic Chemistry, EarlyView.
This study exploits the comparable binding tolerances between the fluorinase enzyme and the A2A adenosine receptor towards the development of novel C‐2 functionalised 5′‐fluorodeoxy‐adenosine (FDA)‐based agonists with enzymatic 18F‐labelling capability for positron emission tomography (PET).
Nicolas Charalambous, Carina Schleidt, Rongfang Liu, Laura H. Heitman, Sergio Dall’Angelo, David O’Hagan, Phillip T. Lowe   +6 more
wiley   +1 more source

Comprehensive analysis of genes associated with necroptosis and pyroptosis in intestinal ischemia-reperfusion injury. [PDF]

PLoS One
Bao S, Sun Y, Hu Y, Lei X, Zhao Y, Li W.
europepmc   +1 more source

Targeting the Nrf2/TGF‐β1/Smad Signaling Pathway: A Novel Strategy for Urolithin A to Alleviate Renal Fibrosis

Food Frontiers, EarlyView.
The diagram of the mechanism of action by which UroA regulates RF. ABSTRACT The global prevalence and mortality rates associated with chronic kidney disease (CKD) have been on a continuous rise over recent decades. Renal fibrosis (RF) serves as a critical factor in the progression of CKD to end‐stage renal disease.
Xue Wu, Jiating Li, Yonghui Dong, Jia Li, Ji Bian, Chao Liu, Hongbo Zhang, Lin Han, Min Wang   +8 more
wiley   +1 more source

Novel Perspectives in Hepatic Ischemia-Reperfusion Injury: The cGAS-STING Pathway. [PDF]

J Inflamm Res
Chen R, Yang T, Jiang Z, Long Y, Qian B, Fu W.   +5 more
europepmc   +1 more source