Results 91 to 100 of about 1,184,407 (410)

Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita, Neel Desai, Abigail R. Manning, Caitlin Pileggi, Sara Manning Peskin, Danielle K. Sandsmark, Dennis L. Kolson, Matthew K. Schindler   +7 more
wiley   +1 more source

Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2 [PDF]

, 2006
FGF-2, a potent multifunctional and neurotrophic growth factor, is widely expressed in the brain and upregulated in cerebral ischemia. Previous studies have shown that intraventricularly or systemically administered FGF-2 reduces the size of cerebral ...
Bohlen und Halbach, Oliver von, Dono, Rosanna, Kiprianova, Irina, Krause, Sonja, Schindowski, Katharina, Schwaninger, Markus, Unsicker, Klaus   +6 more
core  

FK 506 ameliorates the hepatic injury associated with ischemia and reperfusion in rats [PDF]

, 1991
The effect of FK 506 on regeneration of the liver was studied in rats after a two‐thirds partial hepatectomy after 60 min of ischemia of the unresected liver. The animals were divided into three distinct groups of 10 rats each.
Babaeva, Bergmeyer, Borel, Craddock, Craddock, Demetris, Farber, Flye, Francavilla, Francavilla, Gonzalez, Goto, Guzek, Higgins, Kahn, Kawano, Kim, Kim, Marubayashi, Marubayashi, Mazzaferro, Mazzaferro, Meer, Metzger, Miyahara, Ohhori, Sakai, Sakai, Sakai, Sobotka, Starzl, Stromski, Takahashi, Weeds, Yushimira   +34 more
core   +1 more source

Mitochondrial Dysfunction and Myocardial Ischemia-Reperfusion: Implications for Novel Therapies.

Annual Review of Pharmacology and Toxicology, 2017
Mitochondria have emerged as key participants in and regulators of myocardial injury during ischemia and reperfusion. This review examines the sites of damage to cardiac mitochondria during ischemia and focuses on the impact of these defects. The concept
E. Lesnefsky, Qun Chen, B. Tandler, C. Hoppel   +3 more
semanticscholar   +1 more source

CSF Tau Is a Biomarker of Hippocampal Injury in Cryptogenic New‐Onset Refractory Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cryptogenic new‐onset refractory status epilepticus (cNORSE) is a devastating condition characterized by the de novo onset of status epilepticus with unclear etiology. The identification of relevant early biomarkers in cNORSE is important to elucidate pathophysiology, aid clinical decision‐making, and prognosticate outcomes in cNORSE.
Yihui Goh, Yoonhyuk Jang, Soo Jean Shin, Soo Hyun Ahn, Su Yee Mon, Yoon Hee Shin, Kon Chu, Sang Kun Lee, Soon‐Tae Lee   +8 more
wiley   +1 more source

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

Stroke, 2012
Background and Purpose— Mononuclear phagocytes are highly plastic cells that assume diverse phenotypes in response to microenvironmental signals. The phenotype-specific roles of microglia/macrophages in ischemic brain injury are poorly understood.
Xiaoming Hu, Peiying Li, Yanling Guo, Haiying Wang, R. Leak, Songela Chen, Yanqin Gao, Jun Chen   +7 more
semanticscholar   +1 more source

Long‐Term Survival, Burden of Disease, and Patient‐Centered Outcomes in Maximally Treated Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Increasing evidence shows that patients with intracerebral hemorrhage (ICH) can achieve better‐than‐expected outcomes with aggressive therapy. However, real‐world long‐term data, patient‐centered outcomes, and societal measures after maximal ICH treatment are lacking.
Anne Mrochen, Maximilian I. Sprügel, Alexander Sekita, Stefanie Balk, David Haupenthal, Stefan T. Gerner, Hannes Lücking, Arnd Doerfler, Kosmas Macha, Stefan Schwab, Joji B. Kuramatsu, Jochen A. Sembill   +11 more
wiley   +1 more source

CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage

Acta Neuropathologica Communications, 2018
The central nervous system (CNS) contains several types of immune cells located in specific anatomic compartments. Macrophages reside at the CNS borders surrounding the brain vessels, in leptomeningeal spaces and the choroid plexus, where they interact ...
Jordi Pedragosa, Angélica Salas-Perdomo, Mattia Gallizioli, Roger Cugota, Francesc Miró-Mur, Ferran Briansó, Carles Justicia, Fernando Pérez-Asensio, Leonardo Marquez-Kisinousky, Xabier Urra, Anna Gieryng, Bozena Kaminska, Angel Chamorro, Anna M. Planas   +13 more
doaj   +1 more source

Bioresorbable Scaffolds: Contemporary Status and Future Directions

Frontiers in Cardiovascular Medicine, 2020
Percutaneous coronary intervention, which is safe, effective, and timely, has become an important treatment for coronary artery diseases and has been widely used in clinical practice. However, there are still some problems that urgently need to be solved.
Xiang Peng, Xiang Peng, Wenbo Qu, Wenbo Qu, Ying Jia, Ying Jia, Yani Wang, Yani Wang, Bo Yu, Bo Yu, Jinwei Tian, Jinwei Tian, Jinwei Tian   +12 more
doaj   +1 more source

Neuroprotective efficacy of nimesulide against hippocampal neuronal damage following transient forebrain ischemia [PDF]

European Journal of Pharmacology 453(2-3): 189-195 (2002), 2007
Cyclooxygenase-2 is involved in the inflammatory component of the ischemic cascade, playing an important role in the delayed progression of the brain damage. The present study evaluated the pharmacological effects of the selective cyclooxygenase-2 inhibitor nimesulide on delayed neuronal death of hippocampal CA1 neurons following transient global ...
arxiv