Results 21 to 30 of about 965,659 (315)

Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity

open access: yesCirculation, 2021
Supplemental Digital Content is available in the text. Background: The ISCHEMIA trial (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) postulated that patients with stable coronary artery disease (CAD) and ...
H. Reynolds   +22 more
semanticscholar   +1 more source

Relationship of Microchannels and Plaque Erosion in Patients with ST-Segment Elevation Myocardial Infarction: An Optical Coherence Tomography Study

open access: yesCardiology Discovery, 2022
. Objective:. Microchannels are associated with the progression of atherosclerotic vulnerable plaques. However, in patients with culprit optical coherence tomography (OCT)-defined plaque erosion, the knowledge of microchannels and culprit lesion ...
Senqing Jiang   +24 more
doaj   +1 more source

Correction to: Roles of microRNA-34a targeting SIRT1 in mesenchymal stem cells

open access: yesStem Cell Research & Therapy, 2020
An amendment to this paper has been published and can be accessed via the original article.
Fengyun Zhang   +6 more
doaj   +1 more source

Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury

open access: yesFrontiers in Molecular Neuroscience, 2020
The cerebral ischemia injury can result in neuronal death and/or functional impairment, which leads to further damage and dysfunction after recovery of blood supply.
Liquan Wu   +6 more
semanticscholar   +1 more source

Ferroptosis: A Potential Target in Cardiovascular Disease

open access: yesFrontiers in Cell and Developmental Biology, 2022
Ferroptosis is a new form of regulatory cell death characterized by iron-dependent and intracellular lipid peroxidation. Ferroptosis can be divided into two stages.
Yanlong Leng   +9 more
doaj   +1 more source

Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome

open access: yesFrontiers in Cardiovascular Medicine, 2021
Plaque erosion (PE) is one of the most important pathological mechanisms underlying acute coronary syndrome (ACS). The incidence of PE is being increasingly recognized owing to the development and popularization of intracavitary imaging.
Xing Luo   +17 more
doaj   +1 more source

A novel swine model for evaluation of dyslipidemia and atherosclerosis induced by human CETP overexpression

open access: yesLipids in Health and Disease, 2017
Background The mechanism of cholesteryl ester transfer protein (CETP) in lipid metabolism is still unclear. Furthermore, the relationship of CETP and atherosclerosis (AS) has been controversial. As pigs are a good model for both lipid and AS research, we
Tao Chen   +5 more
doaj   +1 more source

Achieved low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio predicts the pathophysiological evolution of lipid-rich plaques in acute coronary syndromes: an optical coherence tomography study

open access: yesFrontiers in Cardiovascular Medicine, 2023
BackgroundAs a novel lipoprotein ratio, baseline low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (LHR) is closely related to the clinical outcomes of acute coronary syndromes (ACS) after percutaneous coronary ...
Luping He   +21 more
doaj   +1 more source

C1q/TNF-Related Protein 9 Attenuates Atherosclerosis by Inhibiting Hyperglycemia-Induced Endothelial Cell Senescence Through the AMPKα/KLF4 Signaling Pathway

open access: yesFrontiers in Pharmacology, 2021
Hyperglycemia-induced endothelial cell senescence has been widely reported to be involved in the pathogenesis of type 2 diabetes mellitus‒accelerated atherosclerosis.
Gang Wang   +22 more
doaj   +1 more source

Omentin-1 effects on mesenchymal stem cells: proliferation, apoptosis, and angiogenesis in vitro

open access: yesStem Cell Research & Therapy, 2017
Background Mesenchymal stem cells (MSCs) are emerging as an extremely promising therapeutic agent for tissue repair. However, limitations exist such as the low numbers of MSCs obtained from donors, and the poor survival and function of donor cells ...
Li Yin   +6 more
doaj   +1 more source

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