Results 21 to 30 of about 1,184,407 (410)

Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury

Frontiers in Molecular Neuroscience, 2020
The cerebral ischemia injury can result in neuronal death and/or functional impairment, which leads to further damage and dysfunction after recovery of blood supply.
Liquan Wu, X. Xiong, Xiaomin Wu, Yingze Ye, Z. Jian, Z. Zhi, Lijuan Gu   +6 more
semanticscholar   +1 more source

C1q/TNF-Related Protein 9 Attenuates Atherosclerosis by Inhibiting Hyperglycemia-Induced Endothelial Cell Senescence Through the AMPKα/KLF4 Signaling Pathway

Frontiers in Pharmacology, 2021
Hyperglycemia-induced endothelial cell senescence has been widely reported to be involved in the pathogenesis of type 2 diabetes mellitus‒accelerated atherosclerosis.
Gang Wang, Gang Wang, Baihe Han, Baihe Han, Ruoxi Zhang, Qi Liu, Qi Liu, Xuedong Wang, Xuedong Wang, Xingtao Huang, Xingtao Huang, Dandan Liu, Dandan Liu, Weishen Qiao, Weishen Qiao, Mengyue Yang, Mengyue Yang, Xing Luo, Xing Luo, Jingbo Hou, Jingbo Hou, Bo Yu, Bo Yu   +22 more
doaj   +1 more source

A novel swine model for evaluation of dyslipidemia and atherosclerosis induced by human CETP overexpression

Lipids in Health and Disease, 2017
Background The mechanism of cholesteryl ester transfer protein (CETP) in lipid metabolism is still unclear. Furthermore, the relationship of CETP and atherosclerosis (AS) has been controversial. As pigs are a good model for both lipid and AS research, we
Tao Chen, Meng Sun, Jia-Qiang Wang, Jin-Jin Cui, Zhong-Hua Liu, Bo Yu   +5 more
doaj   +1 more source

Achieved low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio predicts the pathophysiological evolution of lipid-rich plaques in acute coronary syndromes: an optical coherence tomography study

Frontiers in Cardiovascular Medicine, 2023
BackgroundAs a novel lipoprotein ratio, baseline low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (LHR) is closely related to the clinical outcomes of acute coronary syndromes (ACS) after percutaneous coronary ...
Luping He, Luping He, Boling Yi, Boling Yi, Dirui Zhang, Dirui Zhang, Sining Hu, Sining Hu, Chen Zhao, Chen Zhao, Rui Sun, Rui Sun, Jianlin Ma, Jianlin Ma, Jingbo Hou, Jingbo Hou, Haibo Jia, Haibo Jia, Lijia Ma, Lijia Ma, Bo Yu, Bo Yu   +21 more
doaj   +1 more source

Prevalence of anginal symptoms and myocardial ischemia and their effect on clinical outcomes in outpatients with stable coronary artery disease: data from the international observational CLARIFY registry [PDF]

, 2014
Importance: In the era of widespread revascularization and effective antianginals, the prevalence and prognostic effect of anginal symptoms and myocardial ischemia among patients with stable coronary artery disease (CAD) are unknown.<p></p>
Al-Zaibag, Muayed, Dorian, Paul, Ferrari, Roberto, Ford, Ian, Fox, Kim M., Greenlaw, Nicola, Hu, Dayi, Shalnova, Svetlana, Sokn, Fernando José, Steg, Philippe Gabriel, Tardif, Jean-Claude, Tendera, Michal   +11 more
core   +1 more source

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium.

Circulation, 1986
We have previously shown that a brief episode of ischemia slows the rate of ATP depletion during subsequent ischemic episodes. Additionally, intermittent reperfusion may be beneficial to the myocardium by washing out catabolites that have accumulated ...
C. Murry, R. Jennings, K. Reimer
semanticscholar   +1 more source

Relationship between non-culprit lesion plaque characteristics changes and in-stent neoatherosclerosis formation: 1-year follow-up optical coherence tomography study

Reviews in Cardiovascular Medicine, 2021
The relationship between the in-stent neoatherosclerosis (ISNA) formation and the plaque’s characteristic changes in the non-culprit lesion is unclear.
Lei Xing, Yongpeng Zou, Chao Fu, Xiaoying Fan, Xuedong Wang, Qi Liu, Mengyue Yang, Dandan Liu, Linxing Feng, Jingbo Hou, Xingtao Huang   +10 more
doaj   +1 more source

Omentin-1 effects on mesenchymal stem cells: proliferation, apoptosis, and angiogenesis in vitro

Stem Cell Research & Therapy, 2017
Background Mesenchymal stem cells (MSCs) are emerging as an extremely promising therapeutic agent for tissue repair. However, limitations exist such as the low numbers of MSCs obtained from donors, and the poor survival and function of donor cells ...
Li Yin, Dan Huang, Xinxin Liu, Yongshun Wang, Jingjin Liu, Fang Liu, Bo Yu   +6 more
doaj   +1 more source

Impact of nodular calcification in patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PCI)

BMC Cardiovascular Disorders, 2022
Background Calcified plaque is thought to adversely impact outcomes after percutaneous coronary intervention (PCI). This study sought to evaluate the impact of nodular calcification in patients with acute coronary syndrome treated with primary ...
Abigail Demuyakor, Sining Hu, Ekaterina Koniaeva, Minghao Liu, Ziqian Weng, Chen Zhao, Xue Feng, Luping He, Yishuo Xu, Ming Zeng, Wei Meng, Yanli Sun, Boling Yi, Zhanqun Gao, Yuhan Qin, Haibo Jia, Gary S. Mintz, Bo Yu   +17 more
doaj   +1 more source

Update on the multimodal pathophysiological dataset of gradual cerebral ischemia in a cohort of juvenile pigs: auditory, sensory and high-frequency sensory evoked potentials [PDF]

, 2021
We expand from a spontaneous to an evoked potentials (EP) data set of brain electrical activities as electrocorticogram (ECoG) and electrothalamogram (EThG) in juvenile pig under various sedation, ischemia and recovery states. This EP data set includes three stimulation paradigms: auditory (AEP, 40 and 2000 Hz), sensory (SEP, left and right maxillary ...
arxiv   +1 more source