Results 21 to 30 of about 501,514 (279)
Age and efficacy of remote ischemic conditioning in acute ischemic stroke
CNS Neuroscience & Therapeutics, 2023 AbstractAimsA post hoc analysis of RICAMIS trial to evaluate functional outcomes in relation to patient age.MethodsPatients in RICAMIS were divided into six age groups. The primary outcome was excellent functional outcome at 90 days, defined as modified Rankin Scale (mRS) score of 0–1.
Yu Cui, Jing Zhang, Hui‐Sheng Chen
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What happened if various kinds of postconditioning working on the preconditioned ischemic skin flaps. [PDF]
PLoS ONE, 2013 OBJECTIVE:Ischemic pre-conditioning and post-conditioning are useful manipulations to reduce the undesirable effects of ischemia-reperfusion skin flap each. But the impact of post-conditioning on the pre-conditioning skin flap is not manifested.
Lin Huang
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Remote Ischemic Conditioning: Challenges and Opportunities
Stroke, 2023 Remote ischemic conditioning (RIC) has been investigated as a promising, safe, and well-tolerated nonpharmacological therapy for cardio-cerebrovascular disease over the past 3 decades; variable results have been found when it is used in cerebrovascular versus cardiovascular disease.
Wenbo Zhao +4 more
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Translational challenges of remote ischemic conditioning in ischemic stroke – a systematic review [PDF]
Annals of Clinical and Translational Neurology, 2021 AbstractRemote ischemic conditioning (RIC) has well‐established cardioprotective effects in preclinical studies and promising results in preclinical stroke research. Effective translation from preclinical studies to clinical trials has yet to be accomplished, perhaps because of the use of multiple applications of RIC (e.g., pre‐, per‐, or post ...
Line Fuglsang Hansen +3 more
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Journal of the American College of Cardiology, 2015 In remote ischemic conditioning (RIC), brief, reversible episodes of ischemia with reperfusion in one vascular bed, tissue, or organ confer a global protective phenotype and render remote tissues and organs resistant to ischemia/reperfusion injury. The peripheral stimulus can be chemical, mechanical, or electrical and involves activation of peripheral ...
Heusch, Gerd +4 more
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Ischemic Conditioning in Kidney Transplantation
Journal of Cardiovascular Pharmacology and Therapeutics, 2017 Ischemia–reperfusion injury is a composite of the injury sustained during a period of reduced or absent blood flow to a tissue or organ and the additional insult sustained on reperfusion, which limits the amount of tissue that can be salvaged. Ischemia–reperfusion injury is the predominant insult during kidney transplantation, contributing to graft ...
Veighey, K, MacAllister, R
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Cerebral conditioning: Mechanisms and potential clinical implications
Brain Hemorrhages, 2022 Cerebral conditioning is defined as the mild harmful stimuli applied to the brain before ischemia (preconditioning), during ischemia (perconditioning), immediately, a few hours or days after reperfusion (postconditioning).
Rui Sheng, Jia-Li Chen, Zheng-Hong Qin
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Remote Ischemic Conditioning and Stroke Recovery
Neurorehabilitation and Neural Repair, 2021 Remote ischemic conditioning (RIC) is a noninvasive procedure whereby several periods of ischemia are induced in a limb. Although there is growing interest in using RIC to improve stroke recovery, preclinical RIC research has focused exclusively on neuroprotection, using male animals and the intraluminal suture stroke model, and delivered RIC at times ...
Matthew W. McDonald +7 more
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Ameliorative potential of conditioning on ischemia-reperfusion injury in diabetes
, 2018 Diabetes is a serious metabolic disease characterized by hyperglycemia. Diabetes also leads to several long-term secondary complications. Cardiovascular disease is an important complication of diabetes and is a major contributor to morbidity and ...
Rehni, Ashish K, Dave, Kunjan R
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Somatostatin and Its Receptors in Myocardial Ischemia/Reperfusion Injury and Cardioprotection
Frontiers in Pharmacology, 2021 Little is known about the role of the neuropeptide somatostatin (SST) in myocardial ischemia/reperfusion injury and cardioprotection. Here, we investigated the direct cardiocytoprotective effect of SST on ischemia/reperfusion injury in cardiomyocyte ...
Imre Vörös +31 more
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