Results 41 to 50 of about 501,514 (279)

Adenosine Receptor Activation in the “Trigger” Limb of Remote Pre-Conditioning Mediates Human Endothelial Conditioning and Release of Circulating Cardioprotective Factor(s)

JACC: Basic to Translational Science, 2016
Remote ischemic pre-conditioning (rIPC) has emerged as a potential mechanism to reduce ischemia-reperfusion injury. Clinical data, however, have been mixed, and its physiological basis remains unclear, although it appears to involve release of ...
Hussain Contractor, MBChB, DPhil, Rasmus Haarup Lie, MD, PhD, Colin Cunnington, MBChB, DPhil, Jing Li, PhD, Nicolaj B. Støttrup, MD, PhD, Cedric Manlhiot, BSc, Hans Erik Bøtker, MD, PhD, Michael R. Schmidt, MD, PhD, J. Colin Forfar, MD, PhD, Houman Ashrafian, MB BChir, DPhil, Andrew Redington, MBBS, PhD, Rajesh K. Kharbanda, MBChB, PhD   +11 more
doaj   +1 more source

Major adverse cardiovascular events with remote ischemic conditioning and without remote ischemic conditioning.

, 2013
Major adverse cardiovascular events with remote ischemic conditioning and without remote ischemic conditioning.
Daniel Brevoord (313448), Peter Kranke (313449), Marijn Kuijpers (313450), Benedikt Preckel (313453), Nina Weber (313451), Markus Hollmann (313452)   +5 more
core   +1 more source

The potential mechanism and clinical application value of remote ischemic conditioning in stroke

Neural Regeneration Research
Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may be related to neuroinflammation ...
Yajun Zhu, Xiaoguo Li, Xingwei Lei, Liuyang Tang, Daochen Wen, Bo Zeng, Xiaofeng Zhang, Zichao Huang, Zongduo Guo   +8 more
doaj   +1 more source

Peak troponin release with remote ischemic conditioning and without remote ischemic conditioning.

, 2013
Peak troponin release with remote ischemic conditioning and without remote ischemic conditioning.
Daniel Brevoord (313448), Peter Kranke (313449), Marijn Kuijpers (313450), Benedikt Preckel (313453), Nina Weber (313451), Markus Hollmann (313452)   +5 more
core   +1 more source

Molecular Mechanisms of Renal Ischemic Conditioning Strategies [PDF]

, 2015
Ischemia-reperfusion injury is the leading cause of acute kidney injury in a variety of clinical settings such as renal transplantation and hypovolemic and/or septic shock.
Oltean, Mihai, Krogstrup, N V, Jespersen, B, Krogstrup, Nicoline V., Dor, Frank J. M. F., Jespersen, Bente, Dor, Frank; id_orcid, Nieuwenhuijs-Moeke, Gertrude J., Nieuwenhuijs-Moeke, G J, Kierulf-Lassen, Casper, Oltean, M, Kierulf-Lassen, C   +11 more
core   +1 more source

Hematological, Micro-Rheological, and Metabolic Changes Modulated by Local Ischemic Pre- and Post-Conditioning in Rat Limb Ischemia-Reperfusion

Metabolites, 2021
In trauma and orthopedic surgery, limb ischemia-reperfusion (I/R) remains a great challenge. The effect of preventive protocols, including surgical conditioning approaches, is still controversial.
Csaba Korei, Balazs Szabo, Adam Varga, Barbara Barath, Adam Deak, Erzsebet Vanyolos, Zoltan Hargitai, Ilona Kovacs, Norbert Nemeth, Katalin Peto   +9 more
doaj   +1 more source

Peak troponin release with remote ischemic conditioning and without remote ischemic conditioning in the CABG-surgery sub-group.

, 2013
Peak troponin release with remote ischemic conditioning and without remote ischemic conditioning in the CABG-surgery sub-group.
Daniel Brevoord (313448), Peter Kranke (313449), Marijn Kuijpers (313450), Benedikt Preckel (313453), Nina Weber (313451), Markus Hollmann (313452)   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Remote Ischemic Conditioning: From Bench to Bedside [PDF]

Frontiers in Physiology, 2012
Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury (IRI). It describes an endogenous phenomenon in which the application of one or more brief cycles of non-lethal ischemia and reperfusion to an organ or tissue protects a remote organ or tissue
Lim, SY, Hausenloy, DJ
openaire   +4 more sources

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source