Results 61 to 70 of about 501,514 (279)

Models and methods for conditioning the ischemic brain

Journal of Neuroscience Methods, 2018
In the last decades the need to find new neuroprotective targets has addressed the researchers to investigate the endogenous molecular mechanisms that brain activates when exposed to a conditioning stimulus. Indeed, conditioning is an adaptive biological process activated by those interventions able to confer resistance to a deleterious brain event ...
Vinciguerra, Antonio, Cuomo, Ornella, Cepparulo, Pasquale, Anzilotti, Serenella, Brancaccio, Paola, Sirabella, Rossana, Guida, Natascia, Annunziato, Lucio, Pignataro, Giuseppe   +8 more
openaire   +4 more sources

The Role of Plasma Extracellular Vesicles in Remote Ischemic Conditioning and Exercise-Induced Ischemic Tolerance [PDF]

, 2022
Ischemic conditioning and exercise have been suggested for protecting against brain ischemia-reperfusion injury. However, the endogenous protective mechanisms stimulated by these interventions remain unclear. Here, in a comprehensive translational study,
Bøtker, Hans Erik, Drasbek, Kim Ryun, Yan Yan, Rikke Bæk, Just, Jesper, Kristian Vissing, Vissing, Kristian, Frank de Paoli, Iversen, Nina Kerting, Herskind, Jon, Rasmussen, Peter Mondrup, Katrine Tang Stenz, Jørgen Kjems, Jesper Emil Jakobsgaard, Nyengaard, Jens Randel, Jon Herskind, Sieljacks, Peter, Tingting Gu, Thomas Ravn Lassen, Thomas Skjaerlund Groennebaek, Bæk, Rikke, Anders Gravholt, Gravholt, Anders, Jakob Wang, Kjems, Jørgen, Gu, Tingting, Stenz, Katrine Tang, Jørgensen, Malene Møller; id_orcid, Eugenio Gutiérrez-Jiménez, Lassen, Thomas Ravn, Emil Rindom, Peter Mondrup Rasmussen, Groennebaek, Thomas Skjaerlund, Wang, Jakob, Rindom, Emil, Mathias Jørgensen, Jørgensen, Mathias, de Paoli, Frank, Malene Møller Jørgensen, Jakobsgaard, Jesper Emil, Yan, Yan, Gutiérrez-Jiménez, Eugenio, Hans Erik Bøtker, Jens Randel Nyengaard, Jesper Just, Nina Kerting Iversen, Kim Ryun Drasbek, Peter Sieljacks   +47 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Remote Ischemic Conditioning for Patients With STEMI

Journal of Cardiovascular Pharmacology and Therapeutics, 2017
ST-segment elevation myocardial infarction (STEMI) remains a leading cause of death and morbidity, despite declining incidence and improved short-term outcome in many countries. Although mortality declines in developed countries with easy and fast access to optimized treatment, development of heart failure often remains a challenge in survivors and ...
Schmidt, Michael Rahbek, Rasmussen, Mathis Ersted; id_orcid 0000-0002-7853-3531, Bøtker, Hans Erik; id_orcid 0000-0001-6358-8962   +2 more
openaire   +3 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Circular RNAs and neutrophils: Key factors in tackling asymptomatic moyamoya disease

Brain Circulation, 2019
Moyamoya disease (MMD) represents a rare steno-occlusive disorder affecting the terminal ends of the internal carotid artery and promoting the development of a poor, abnormal vascular network at the brain's base.
Sydney Corey, Yumin Luo
doaj   +1 more source

The antihypertensive effect of remote ischemic conditioning in spontaneously hypertensive rats

Frontiers in Immunology, 2023
PurposeLimb remote ischemic conditioning (LRIC) may be an effective method to control hypertension. This study investigated whether LRIC decreases blood pressure by regulating the hypertensive inflammatory response in spontaneously hypertensive rats (SHR)
Xiaohua Li, Xiaohua Li, Changhong Ren, Sijie Li, Wenbo Zhao, Peifu Wang, Xunming Ji   +6 more
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Supplementary Material for: Molecular Mechanisms of Renal Ischemic Conditioning Strategies

, 2015
Ischemia-reperfusion injury is the leading cause of acute kidney injury in a variety of clinical settings such as renal transplantation and hypovolemic and/or septic shock.
Aarhus University Hospital, Oltean, Mihai, Erasmus University Medical Center, University of Gothenburg, Krogstrup, Nicoline V., Dor, Frank J. M. F., Jespersen, Bente, Nieuwenhuijs-Moeke, Gertrude J., Kierulf-Lassen, Casper   +8 more
core   +3 more sources

Remote Ischemic Conditioning and Renal Protection

Journal of Cardiovascular Pharmacology and Therapeutics, 2017
Over the course of the last 2 decades, the concept of remote ischemic conditioning (RIC) has attracted considerable research interest, because RIC, in most of its embodiments offers an inexpensive way of protecting tissues against ischemic damage inflicted by a number of medical conditions or procedures.
Giannopoulos, G., Vrachatis, D.A., Panagopoulou, V., Vavuranakis, M., Cleman, M.W., Deftereos, S.   +5 more
openaire   +3 more sources