Results 51 to 60 of about 10,945 (163)

Pré-condicionamento isquémico remoto do miocárdio: dos mecanismos fisiopatológicos à aplicação na prática clínica

Revista Portuguesa de Cardiologia, 2013
Resumo: Curtos períodos de isquemia do miocárdio seguida de reperfusão induzem um mecanismo de cardioproteção quando este é depois submetido a um período de isquemia prolongada, um fenómeno designado pré-condicionamento isquémico.Além da sua aplicação ...
José F. Costa, Ricardo Fontes-Carvalho, Adelino F. Leite-Moreira   +2 more
doaj   +1 more source

New Insights on Heat Shock Proteins as Regulators of Reactive Oxygen Species Across Various Stressors in Diseases

Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar, Triveni Kodi, Adarsh Gopinathan, Bharath Harohalli Byregowda, Krishnadas Nandakumar, Anoop Kishore   +5 more
wiley   +1 more source

Mitochondrial Intercellular Transfer via Platelets After Physical Training Exerts Neuro‐Glial Protection Against Cerebral Ischemia

MedComm, Volume 7, Issue 2, February 2026.
Treadmill training protects against white matter injury and reduces cerebral infarction. Muscle‐derived mitochondrial transfer via platelets is promoted by treadmill training. Platelet transfusion emerges as a potential low‐risk therapeutic strategy for sequelae and vascular dementia.
Toshiki Inaba, Nobukazu Miyamoto, Kenichiro Hira, Chikage Kijima, Yoshifumi Miyauchi, Hai‐Bin Xu, Kazo Kanazawa, Yuji Ueno, Nobutaka Hattori   +8 more
wiley   +1 more source

Myocardial remote ischemic preconditioning: From pathophysiology to clinical application

Revista Portuguesa de Cardiologia (English Edition), 2013
Short periods of myocardial ischemia followed by reperfusion induce a cardioprotective mechanism when the myocardium is subsequently subjected to a prolonged period of ischemia, a phenomenon known as ischemic preconditioning. As well as its application in the myocardium, ischemic preconditioning can also be induced by brief interruptions of blood flow ...
José F, Costa, Ricardo, Fontes-Carvalho, Adelino F, Leite-Moreira   +2 more
openaire   +2 more sources

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, Volume 13, Issue 3, 14 January 2026.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

Remote ischemic preconditioning in myocardial protection in hemodialysis patients

International Journal of General Medicine, 2018
Remote ischemic preconditioning (RIPC) is a procedure that generates a brief period of ischemia followed by reperfusion. The role of RIPC in protecting myocardial ischemia during hemodialysis is not yet established. The aim of the study was to evaluate RIPC myocardial protection as evaluated by ultrasensitive I troponin in hemodialysis outpatients.A ...
Marcelo Bacci, Livia Vasconcelos, Neif Murad, Antonio Carlos Chagas, Ana Carolina Capuano, Beatriz Alves, Edimar Pereira, Ligia Azzalis, Virginia Junqueira, Fernando Fonseca   +9 more
openaire   +5 more sources

Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley   +1 more source

myocardial responses to ischemia

Терапевтический архив, 2010
The paper details the types of a myocardial response to impaired blood flow, such as myocardial stunning, hibernation, ischemic preconditioning, warm-up phenomenon, ischemic postconditoning, remodeling, and infarction.
Viktor Gennad'evich Borisenko, Elena Aleksandrovna Gubareva, Azamat Khalidovich Kade, V G Borisenko, E A Gubareva, A Kh Kade   +5 more
doaj  

Melatonin‐engineered MSCs‐exosomes deliver USP4 to stabilise ARNTL and inhibit clock rhythmic ferroptosis for enhanced flap survival

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
• Sleep restriction induces clock rhythmic ferroptosis, leading to skin flap necrosis. • MEXOs deliver USP4 to stabilise ARNTL, restoring circadian rhythm and inhibiting ferroptosis. • The METTL3/YTHDF1 m6A axis up‐regulates USP4 in melatonin‐preconditioned BMSCs.
Xiaoqiong Jiang, Yu Wang, Xuanlong Zhang, Huiming Deng, Liangyu Fang, Chaire Tafadzwa, Jiangnan Yao, Hao Chen, Anqi Ye, Kailiang Zhou, Xiangwei Ling, Jian Xiao   +11 more
wiley   +1 more source

Angiogenic Potential of Small Extracellular Vesicles Produced by Stimulated Mesenchymal Stromal Cells Under Hypoxic Conditions

Journal of Extracellular Biology, Volume 5, Issue 1, January 2026.
ABSTRACT Regenerative vascular medicine research has positioned mesenchymal stromal cells (MSCs) as a leading candidate to treat ischemic diseases. Recent studies have highlighted the emerging role of small extracellular vesicles (sEVs) produced by MSCs in their own potential.
Nada Serhal, Bertrand Brassart, Lise Nannan, Sandra Audonnet, Christine Terryn, Gaël Poitevin, Pascale Cornillet‐Lefebvre, Florine Dubuisson, Hélène Peyret, Philippe Nguyen, Claire Tournois   +10 more
wiley   +1 more source