Results 51 to 60 of about 11,601 (142)

Effect of Electroacupuncture and Moxibustion Preconditioning on Blood Endothelin and Creatine Kinase Contents and Myocardial HSP 70 Expression in Rabbits with Myocardial Ischemia-reperfusion Injury

针刺研究, 2014
Objective To observe the effect of electroacupuncture(EA)and moxibustion(Moxi)preconditioning of bilateral"Neiguan"(PC 6)on plasma endothelin(ET)and serum creatine kinase(CK)contents and myocardial hot shock protein70(HSP 70)expression in myocardial ...
WANG Chao, XIE Wen-juan, LIU Mi, YAN Jie, ZHANG Jia-li, LIU Zhao, GUO Li-na   +6 more
doaj   +2 more sources

The Health Benefits of Exercise: Molecular and Cellular Mechanisms

MedComm, Volume 7, Issue 9, September 2026.
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Peifeng Ying, Huilin Wang, Xiu Lu, Wenjuan Zhang, Zhehao Lin, Kai Wang, Shangxuan Li, Lu Chen, Mingchao Jiang, Sarkawt Hamad, Yi Wang, Jianmin Wu, Shukuan Ling   +12 more
wiley   +1 more source

Tissue‐Resident Macrophage in Inflammation and Cancer

MedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang, Jiangbo Fan, Wenyi Liu, Di Liu, Rui Wang, Yuanyang Wang, Jianhui Sun, Huacai Zhang, Qingli Cai, Zhe Xu, Fang Xu, Jianxin Jiang, Zhen Wang, Ling Zeng   +13 more
wiley   +1 more source

Cardioprotection induced in a mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus

Nature Communications, 2017
Various forms of preconditioning can prevent ischemic-reperfusion injury after myocardial infarction. Here, the authors show that in mice, the presence of chronic neuropathic pain can have a cardioprotective effect, and that this is dependent on neural ...
Yi-Fen Cheng, Ya-Ting Chang, Wei-Hsin Chen, Hsi-Chien Shih, Yen-Hui Chen, Bai-Chuang Shyu, Chien-Chang Chen   +6 more
doaj   +1 more source

Applications of Mesenchymal Stromal Cells for Treatment of Diseases

MedComm, Volume 7, Issue 9, September 2026.
This schematic summarizes the major therapeutic mechanisms of MSCs across different disease systems and highlights factors associated with MSCs dysfunction, together with current strategies to enhance MSCs function and therapeutic efficacy. This summary diagram illustrates that MSCs exert therapeutic effects in various diseases through multiple ...
Dongmei Xue, Yongsheng Li, Lei Wu
wiley   +1 more source

Therapeutic Potential of Gene‐Modified MSC‐Exos in Insulin Resistance: Mitochondrial Crosstalk and miRNA Regulation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.
ABSTRACT Insulin resistance (IR) is the key driver of type 2 diabetes mellitus, metabolic dysfunction‐associated steatotic liver disease, and cardiometabolic disorders. Mesenchymal stem cell‐derived exosomes (MSC‐Exos) as a potent cell‐free alternative can deliver miRNAs, proteins, and mitochondrial regulators to reactivate the IRS1/PI3K/Akt/GLUT4 axis.
Qinghua Jia, Bing Li, Yuan Xing, Yuanyuan Zhang, Baodong Gao, Xiangying Li, Xiaoqin Ha   +6 more
wiley   +1 more source

RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study: Myocardial Dysfunction, Postoperative Neurocognitive Dysfunction, and 1 Year Follow‐Up

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundRemote ischemic preconditioning (RIPC) has been suggested to protect against certain forms of organ injury after cardiac surgery. Previously, we reported the main results of RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study, a ...
Patrick Meybohm, Madeline Kohlhaas, Christian Stoppe, Matthias Gruenewald, Jochen Renner, Berthold Bein, Martin Albrecht, Jochen Cremer, Mark Coburn, Gereon Schaelte, Andreas Boening, Bernd Niemann, Michael Sander, Jan Roesner, Frank Kletzin, Haitham Mutlak, Sabine Westphal, Rita Laufenberg‐Feldmann, Marion Ferner, Ivo F. Brandes, Martin Bauer, Sebastian N. Stehr, Andreas Kortgen, Maria Wittmann, Georg Baumgarten, Tanja Meyer‐Treschan, Peter Kienbaum, Matthias Heringlake, Julika Schoen, Sascha Treskatsch, Thorsten Smul, Ewa Wolwender, Thomas Schilling, Georg Fuernau, Holger Bogatsch, Oana Brosteanu, Dirk Hasenclever, Kai Zacharowski   +37 more
doaj   +1 more source

Furong Tongmai Capsule Ameliorates Atherosclerosis in ApoE−/− Mice by Modulating Gut Microbiota, Arachidonic Acid Metabolism and Macrophage Polarization

Journal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.
ABSTRACT Furong Tongmai capsule (FRTM) is a traditional Chinese medicine formula with reported lipid‐lowering and anti‐inflammatory activities, but its mechanisms in atherosclerosis (AS) remain unclear. In ApoE−/− mice fed a high‐fat diet, FRTM administration improved serum lipid profiles by reducing total cholesterol, triglycerides and low‐density ...
Shuquan Lv, Hanzhou Li, Yuming Wang, Xiuxiu Sang, Feng Wang, Jing Yang, Lirong Fan, Ziang Ma, Lixin Wang, Yuhong Bian, Huantian Cui   +10 more
wiley   +1 more source

Upregulation of vascular endothelial growth factor receptor-1 contributes to sevoflurane preconditioning–mediated cardioprotection

Drug Design, Development and Therapy, 2018
Bin Qian,1 Yang Yang,2 Yusheng Yao,3 Yanling Liao,3 Ying Lin3 1Department of Anesthesiology, People’s Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China; 2Department of Anesthesiology, West China ...
Qian B, Yang Y, Yao Y, Liao Y, Lin Y
doaj  

Low‐dose X‐ray radiation induces an adaptive response: A potential countermeasure to galactic cosmic radiation exposure

Experimental Physiology, Volume 111, Issue 9, Page 3919-3927, 1 September 2026.
Abstract Space exploration involves many dangers including galactic cosmic radiation (GCR). This class of radiation includes high‐energy protons and heavy ionizing ions. NASA has defined GCR as a carcinogenic risk for long‐duration space missions. To date, no clear strategy has been developed to counter chronic GCR exposure.
Siena Edwards, Jessica Adams, Anastasia Tchernikov, John G. Edwards   +3 more
wiley   +1 more source