Results 61 to 70 of about 10,945 (163)

Ischemic preconditioning activates prosurvival kinases and reduces myocardial apoptosis

Journal of the Chinese Medical Association, 2015
Ischemic preconditioning has been reported to protect the myocardium against ischemia and reperfusion injury. The underlying mechanisms have been extensively investigated but are not fully elucidated. In this study, we investigated the role of apoptosis in ischemic preconditioning protection and the signal pathways involved.Myocardial ischemia and ...
Lai, Chang-Chi, Tang, Chia-Yu, Chiang, Shu-Chiung, Tseng, Kuo-Wei, Huang, Cheng-Hsiung   +4 more
openaire   +2 more sources

Organ Transplantation: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 1, January 2026.
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley   +1 more source

Adenosine Preconditioning versus Ischemic Preconditioning in Patients undergoing Off-Pump Coronary Artery Bypass (OPCAB)

Journal of Tehran University Heart Center, 2015
Background: During off-pump coronary artery bypass (OPCAB), the heart is subjected to ischemic and reperfusion injury. Preconditioning is a mechanism that permits the heart to tolerate myocardial ischemia. The aim of this study was to compare the effects
SeyedKhalil Forouzannia, MohammadHassan Abdollahi, SeyedJalil Mirhosseini, Mehdi Hadadzadeh, Rouholla Zarepur, Ehsan Zarepur, Omid Beiki, Mohammadtaghi Sarebanhassanabadi   +7 more
doaj  

The tole of ischemic preconditioning in acute myocardial infarction

Medicinski pregled, 2005
Introduction Ischemic preconditioning is a phenomenon in which brief episodes of ischemia and reperfusion increase myocardial tolerance and substantially reduce the infarction size. Case report Two patients with acute left anterior descending artery occlusion received fibrinolytic therapy within 6 hours of symptom onset, but nevertheless developed ...
Andelka, Ristić, Milorad, Damjanović, Branislav, Baskot, Sasa, Rafaelovski   +3 more
openaire   +3 more sources

Cardioprotection induced in a mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus

Nature Communications, 2017
Various forms of preconditioning can prevent ischemic-reperfusion injury after myocardial infarction. Here, the authors show that in mice, the presence of chronic neuropathic pain can have a cardioprotective effect, and that this is dependent on neural ...
Yi-Fen Cheng, Ya-Ting Chang, Wei-Hsin Chen, Hsi-Chien Shih, Yen-Hui Chen, Bai-Chuang Shyu, Chien-Chang Chen   +6 more
doaj   +1 more source

RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study: Myocardial Dysfunction, Postoperative Neurocognitive Dysfunction, and 1 Year Follow‐Up

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundRemote ischemic preconditioning (RIPC) has been suggested to protect against certain forms of organ injury after cardiac surgery. Previously, we reported the main results of RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study, a ...
Patrick Meybohm, Madeline Kohlhaas, Christian Stoppe, Matthias Gruenewald, Jochen Renner, Berthold Bein, Martin Albrecht, Jochen Cremer, Mark Coburn, Gereon Schaelte, Andreas Boening, Bernd Niemann, Michael Sander, Jan Roesner, Frank Kletzin, Haitham Mutlak, Sabine Westphal, Rita Laufenberg‐Feldmann, Marion Ferner, Ivo F. Brandes, Martin Bauer, Sebastian N. Stehr, Andreas Kortgen, Maria Wittmann, Georg Baumgarten, Tanja Meyer‐Treschan, Peter Kienbaum, Matthias Heringlake, Julika Schoen, Sascha Treskatsch, Thorsten Smul, Ewa Wolwender, Thomas Schilling, Georg Fuernau, Holger Bogatsch, Oana Brosteanu, Dirk Hasenclever, Kai Zacharowski   +37 more
doaj   +1 more source

Upregulation of vascular endothelial growth factor receptor-1 contributes to sevoflurane preconditioning–mediated cardioprotection

Drug Design, Development and Therapy, 2018
Bin Qian,1 Yang Yang,2 Yusheng Yao,3 Yanling Liao,3 Ying Lin3 1Department of Anesthesiology, People’s Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China; 2Department of Anesthesiology, West China ...
Qian B, Yang Y, Yao Y, Liao Y, Lin Y
doaj  

Comparison of the proteomic landscape in experimental ischemia reperfusion with versus without ischemic preconditioning

Scientific Reports
Myocardial ischemic preconditioning (IPC) enhances myocardial resilience to ischemic injury. Myocardial stunning is a transient, reversible dysfunction, while necrosis involves irreversible cell death. The relationship between IPC, stunning, and necrosis
Yalda Kakaei, Shafaat Hussain, Ahmed Elmahdy, Evelin Berger, Aaron Shekka Espinosa, Valentyna Sevastianova, Zahra Sheybani, Amin Al-Awar, Mana Kalani, Sandeep Jha, Ermir Zulfaj, Amirali Nejat, Abhishek Jha, Tetiana Pylova, Maryna Krasnikova, Erik Axel Andersson, Vagner Ramon Rodrigues Silva, Elmir Omerovic, Björn Redfors   +18 more
doaj   +1 more source

PREINFARCTION ANGINA AS A CLINICAL FORM OF THE ISCHEMIC PRECONDITIONING PHENOMENON

Кардиоваскулярная терапия и профилактика, 2014
Brief episodes of myocardial ischemia initiate a cascade of endogenous mechanisms which protect the heart during further ischemic attack. This phenomenon is called an ischemic preconditioning.
E. A. Lykasova, V. V. Todosiychuk, V. A. Kuznetsov, Y. A. Yurkina   +3 more
doaj   +1 more source

Adaptation to hypoxia and ischemic preconditioning: pathophysiologic and clinical aspects of cardioprotection in patients with coronary disease

КардиоСоматика, 2015
Research of cardioprotection and endogenous methods of nonspecific myocardial protection - adaptation to hypoxia and ischemic preconditioning grows rapidly nowadays.
N. P Liamina, E. V Kotelnikova, E. S Karpova, E. A Biziaeva, S. V Liamina   +4 more
doaj