Results 131 to 140 of about 25,118 (249)

Preconditioning does not prevent post-ischemic dysfunction in aging heart.

open access: yes, 1995
Objectives. This study was performed to investigate the effect of single or multiple brief periods of ischemia and the administration of exogenous norepinephrine before a more prolonged ischemic period and after reperfusion in adult and senescent ...
Cacciatore, Francesco   +24 more
core   +1 more source

Modulation of KATP channels by diazoxide preserves mitochondrial function and barrier integrity under staurosporine‐induced epithelial stress

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 12, Page 3213-3233, June 2026.
Background and Purpose Intestinal barrier dysfunction caused by mitochondrial stress, oxidative damage and apoptosis, are hallmarks of dysbiosis‐associated gastrointestinal (GI) disorders. Staurosporine causes downstream features of dysbiosis‐induced epithelial damage.
Fatima Maqoud   +9 more
wiley   +1 more source

Comparison of direct versus remote ischemic preconditioning [PDF]

open access: yes, 2013
학위논문 (석사)-- 서울대학교 대학원 : 의학과 흉부외과학 전공, 2013. 2. 김기봉.Background: Ischemic preconditioning, direct or remote, has been known to protect the myocardium against lethal ischemic injury.
오세진
core  

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

open access: yesCell Proliferation, Volume 59, Issue 6, June 2026.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang   +8 more
wiley   +1 more source

Deciphering Freezing of Gait: What Neuropathology Reveals About an Episodic Phenomenon

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 12, June 2026.
Freezing of gait (FoG) occurs across Parkinson's disease, multiple neurodegenerative conditions and non‐neurodegenerative disorders. This review synthesizes the structural, neurochemical and proteinopathic substrates underlying FoG, showing how cumulative damage to distributed locomotor circuits—compounded by overlapping pathologies—progressively ...
Gabor G. Kovacs
wiley   +1 more source

Unveiling protective mechanisms of wild olive (acebuche) oil in retinal pigment epithelial cells with hypertensive phenotype

open access: yesThe Journal of Physiology, Volume 604, Issue 11, Page 4166-4185, 1 June 2026.
Abstract figure legend Circulating extracellular vesicles (EVs) derived from acebuche (ACE) oil‐ and extra virgin olive oil (EVOO)‐fed mice modulate nitric oxide (NO) metabolism in the retinal pigment epithelial cell line (ARPE19) with a hypertensive phenotype induced by angiotensin II (AngII).
Álvaro Santana‐Garrido   +6 more
wiley   +1 more source

Ischemic preconditioning in the elderly

open access: yes, 2010
A mild stress such as brief ischemic episodes may protect the heart from a successive and more prolonged myocardial ischemia (ischemic preconditioning).
Abete, Pasquale   +6 more
core  

Experimental substantiation of an opportunity of the use of vardenafil for pharmacological preconditioning in surgery

open access: yesКубанский научный медицинский вестник, 2015
The possibility of vardenafil using for pharmacological preconditioning in surgery is studied. Experiment was carried out on Wistar rats. The influence of vardenafil on the survival of pedicled isolated skin flap and the state of the microvasculature in ...
I. M. Kolesnik   +2 more
doaj  

ISCHEMIC PRECONDITIONING AND ITS CARDIOPROTECTIVE EFFECT IN POST-INTERVENTION CARDIAC REHABILITATION PROGRAMMES FOR PATIENTS WITH CORONARY HEART DISEASE

open access: yesРоссийский кардиологический журнал, 2012
In patients with coronary heart disease (CHD), ischemic preconditioning facilitates the mechanisms of cardioprotection and metabolic adaptation to non-fatal ischemia, which is particularly important for the individuals with reduced coronary flow reserve.
E. S. Karpova   +2 more
doaj  

PRECONDITIONING AS PROTECTION AGAINST ISCHEMIC MYOCARDIAL INJURY

open access: yesActa Biomedica Scientifica, 2013
The article discusses the phenomenon of metabolic adaptation to ischemia after repeated episodes of transient reduction in myocardial perfusion. It is shown that the phenomenon of ischemic preconditioning is to significantly improve the stability of the ...
M. G. Shurygin   +3 more
doaj  

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