Results 121 to 130 of about 262,486 (214)

MicroRNAs Induced During Ischemic Preconditioning

, 2010
Background and Purpose— MicroRNAs (miRNA) are single-stranded short RNA molecules that regulate gene expression by either degradation or translational repression of mRNA.
Kon Chu, Jae-Kyu Roh, Lee, Soon-Tae, Sang Kun Lee, Hye-Jin Yoon, Manho Kim, Ki-Ho Park, Jung, Keun-Hwa, Bae, Eun-Kee, Roh, Jae-Kyu, Kim, Manho, Daejong Jeon, Soon-Tae Lee, Keun-Hwa Jung, Kyoung-Mook Kang, Yoon, Hye-Jin, Park, Ki-Ho, Lee, Sang Kun, Jeon, Daejong, Eun-Kee Bae, Chu, Kon   +20 more
core   +1 more source

Inter‐Set Blood‐Flow Restriction Increases Peripheral Physiological Stress While Preserving Repeated‐Sprint Mechanical Output in Trained Athletes

European Journal of Sport Science, Volume 26, Issue 9, September 2026.
ABSTRACT Inter‐set blood‐flow restriction (BFR) may increase the physiological stimulus of repeated‐sprint exercise without compromising mechanical output, but evidence in trained athletes is limited. In a randomized crossover design, 26 national‐level male badminton players completed three 5 × 5‐s cycling sprints (25‐s intra‐set rest, 3.5‐min inter ...
Tianhao Zheng, Leyi Jiang, Yan chen, Dapeng Bao, Olivier Girard   +4 more
wiley   +1 more source

Biomarkers for Ischemic Preconditioning: Finding the Responders

, 2014
Ischemic preconditioning is emerging as an innovative and novel cytoprotective strategy to counter ischemic vascular disease. At the root of the preconditioning response is the upregulation of endogenous defense systems to achieve ischemic tolerance ...
Sacco, RL, Ralph L Sacco, Dave, KR, Kunjan R Dave, Miguel A Perez-Pinzon, Sebastian Koch, Koch, S, Della-Morte, David, David Della-Morte, Sacco, Ralph L, Perez-Pinzon, Miguel A, DELLA MORTE, DAVID, Koch, Sebastian, Perez Pinzon, MA, Dave, Kunjan R   +14 more
core   +1 more source

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

iNew Medicine, Volume 2, Issue 3, September 2026.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng, Wenhui Zhao, Min Wang, Xianwen Wang   +3 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Management of Refractory and Difficult‐To‐Treat Inflammatory Bowel Disease: An Expert Opinion Review

JCC Plus, Volume 1, Issue 5, September 2026.
This expert opinion offers a practical framework for refractory and difficult‐to‐treat IBD: confirm inflammation objectively, distinguish pharmacologic from structural and functional disease, and then escalate. Across ten clinical questions, the evidence is often limited to case series, and the resulting statements are identified as expert opinion ...
Filiz Akyuz, Oguz Kagan Bakkaloglu, Nalan Gulsen Unal, Ismail Hakki Kalkan, Mehmet Arhan, Ibrahim Hatemi, Taylan Kav, Murat Toruner, Hale Akpinar, Ahmet Tezel, Aykut Ferhat Celik   +10 more
wiley   +1 more source

Acute hyperglycemia abolishes ischemic preconditioning in vivo

, 1998
Ischemic preconditioning provides a powerful means to reduce myocardial infarct size in vivo and has been proposed to limit the extent of myocardial infarction in patients.
Paul S. Pagel, Judy R. Kersten, Todd J. Schmeling, Karl G. Orth, David C. Warltier   +4 more
core   +1 more source

Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li, Qian Zhang, Yichen Wu, Ruixue Huang   +3 more
wiley   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

MedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao, Lin Ye, Tianqi Jiang, Mengyuan Liu, Yuxia Zhou   +4 more
wiley   +1 more source

The Health Benefits of Exercise: Molecular and Cellular Mechanisms

MedComm, Volume 7, Issue 9, September 2026.
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Peifeng Ying, Huilin Wang, Xiu Lu, Wenjuan Zhang, Zhehao Lin, Kai Wang, Shangxuan Li, Lu Chen, Mingchao Jiang, Sarkawt Hamad, Yi Wang, Jianmin Wu, Shukuan Ling   +12 more
wiley   +1 more source