Results 101 to 110 of about 25,118 (249)

The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities

Disease Models & Mechanisms, 2014
Following a period of ischemia (local restriction of blood supply to a tissue), the restoration of blood supply to the affected area causes significant tissue damage.
Kieran McCafferty, Suzanne Forbes, Christoph Thiemermann, Muhammad M. Yaqoob   +3 more
doaj   +1 more source

Cardioprotection by remote ischemic preconditioning exhibits a signaling pattern different from local ischemic preconditioning

, 2011
Remote ischemic preconditioning (RIPC) and local ischemic preconditioning (IPC) protect the myocardium from subsequent ischemia/reperfusion (I/R) injury.
Grüber, Yvonne, Yvonne Grüber, Nicole M. Heinen, Ragnar Huhn, Carmen Barthuber, Benedikt H. Pannen, Huhn, Ragnar, Heinen, Nicole M., Görgens, Jessica I., Bauer, Inge, Jessica I. Görgens, Inge Bauer, Benedikt Preckel, Preckel, Benedikt, Pütz, Verena E., Pannen, Benedikt H., Barthuber, Carmen, Verena E. Pütz   +17 more
core   +1 more source

The impact of a single episode of remote ischemic preconditioning on myocardial injury after elective percutaneous coronary intervention [PDF]

, 2017
Introduction : Myocardial injury after percutaneous coronary intervention (PCI) occurs in approximately 30% of procedures, and is related to worse prognosis.
Taylan, Gokay, Kenan Yalta, Gurlertop, Hanefi Y., Fatih Özçelik, Meryem Aktoz, Yalta, Kenan, Yüksel Aksoy, Yilmaztepe, Mustafa A., Aktoz, Meryem, Galip Ekuklu, Ozcelik, Fatih, Mustafa A. Yılmaztepe, Hanefi Y. Gürlertop, Gökay Taylan, Aksoy, Yuksel   +14 more
core   +1 more source

Small‐conductance Ca2⁺‐activated K⁺ channels in cardiac excitation–contraction coupling: Bridging mitochondria, sarcolemma and antiarrhythmic therapy

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev, Alexey V. Glukhov, Vladimir Bogdanov, Aleksei S. Averin, Roland Veress, Bum‐Rak Choi, Shanna Hamilton, Andriy E. Belevych   +7 more
wiley   +1 more source

Ischemic preconditioning in the younger and aged heart [PDF]

, 2011
: Ischemic preconditioning is the effect of brief ischemic episodes which protect the heart from the following more prolonged ischemic episode. This mechanism is effective in younger but not in aged heart.
Abete, Pasquale, Testa, Gianluca, Cacciatore, Francesco, Langellotto, Assunta, Rengo, Franco, Della-Morte, David, Galizia, Gianluigi   +6 more
core   +1 more source

The Ethical Cost of Delay: Lessons From an Acute Haemorrhagic Neurological Emergency in a Low‐Resource Setting

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Prompt recognition and early intervention are critical in the management of intracerebral hemorrhage. This case demonstrates how system‐level diagnostic and referral delays in a low‐resource setting can worsen outcomes, underscoring the ethical imperative for coordinated emergency pathways and equitable access to neurosurgical care.
Kwasi Asare Boadi, Dennis Awedam Achio, Eunice Wilberforce A. Achio   +2 more
wiley   +1 more source

Remote ischemic preconditioning in major vascular surgery

, 2009
Remote ischemic preconditioning is a physiologic mechanism in mammalian species whereby brief exposure to nonlethal ischemia in one tissue confers protection against a prolonged ischemic insult in a distant tissue. first described almost 15 years ago, it
Tang, Tjun Y., Gaunt, Michael E., Walsh, Stewart R., Sadat, Umar   +3 more
core   +1 more source

Modified Sleep Apnea Severity Index and Cardiovascular Risk in CPAP‐Intolerant OSA Patients

The Laryngoscope, Volume 136, Issue 7, Page 3262-3270, July 2026.
The modified sleep apnea severity index (mSASI) combines patient anatomy, weight, sleep study metrics, and symptoms into a composite OSA index ranging from 1 (least severe) to 3 (most severe). Our study found that mSASI correlated better with baseline cardiovascular risk measured by the 5‐year Framingham Risk Score compared to the AHI.
Praneet C. Kaki, Jennifer A. Goldfarb, Melissa Xu, Daniel J. Campbell, Nicole Molin, Erin Creighton, Thomas M. Kaffenberger, Maurits Boon, Colin Huntley   +8 more
wiley   +1 more source

Remote ischemic preconditioning in myocardial protection in hemodialysis patients

, 2018
Marcelo R Bacci,1 Livia Y Vasconcelos,1 Neif Murad,2 Antonio Carlos P Chagas,2 Ana Carolina Capuano,1 Beatriz CA Alves,3 Edimar C Pereira,4 Ligia A Azzalis,4 Virginia BC Junqueira,4 Fernando LA Fonseca3,4 1Department of General Practice, 2Department of ...
Pereira EC, Murad N, Vasconcelos LY, Junqueira VB, Alves BC, Bacci MR, Capuano AC, Azzalis LA, Fonseca FL, Chagas AC   +9 more
core  

Blistering barnacles: Space physiology in The Adventures of Tintin

Experimental Physiology, EarlyView.
Jacob P. Hartmann, Mathis B. Mottelson, Rasmus H. Dahl, Ronni R. Plovsing, Ronan M. G. Berg   +4 more
wiley   +1 more source