The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology [PDF]
Due to its poor capacity for regeneration, the heart is particularly sensitive to the loss of contractile cardiomyocytes. The onslaught of damage caused by ischaemia and reperfusion, occurring during an acute myocardial infarction and the subsequent ...
A Ames 3rd +117 more
core +6 more sources
Abstract Space exploration involves many dangers including galactic cosmic radiation (GCR). This class of radiation includes high‐energy protons and heavy ionizing ions. NASA has defined GCR as a carcinogenic risk for long‐duration space missions. To date, no clear strategy has been developed to counter chronic GCR exposure.
Siena Edwards +3 more
wiley +1 more source
Clinical Application of Ischemic Preconditioning in the Elderly
A mild stress such as brief ischemic episodes may protect the heart from a successive and more prolonged myocardial ischemia (ischemic preconditioning).
Pasquale Abete +6 more
doaj +1 more source
The effect of remote ischemic preconditioning and aerobic exercise on myocardial BIP and eIF2α gene expression in male rats with myocardial infarction [PDF]
Background. Endoplasmic reticulum stress contributes to the development of cardiovascular diseases. In contrast, regular physical exercise has been considered a powerful tool to prevent and control cardiovascular diseases.
Atefeh Ghorbanipor +3 more
doaj +1 more source
Antiarrhythmic effect of ischemic preconditioning during low-flow ischemia: The role of bradykinin and sarcolemmal versus mitochondrial ATP-sensitive K+ channels [PDF]
. : Short episodes of ischemia (ischemic preconditioning) protect the heart against ventricular arrhythmias during zero-flow ischemia and reperfusion. However, in clinics, many episodes of ischemia present a residual flow (low-flow ischemia).
Barbosa, Vânia +7 more
core
Effect of Staged Preconditioning on BiochemicalMarkers in the Patients Undergoing Coronary Artery Bypass Grafting [PDF]
The present study has investigated the effectiveness of staged-preconditioning, in both remote and target organs. After IP the myocardial release of the biochemicalmarkers including, creatine phosphokinase (CPK), cardiac creatine kinase (CK-MB ...
باباپور, بهزاد +5 more
core +3 more sources
Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]
Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Becker, Bernhard F. +4 more
core +1 more source
Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley +1 more source
OBJECTIVES: Intestinal ischemia/reperfusion often leads to acute lung injury and multiple organ failure. Ischemic preconditioning is protective in nature and reduces tissue injuries in animal and human models.
Muhammad Tahir +6 more
doaj +1 more source
Ischemic preconditioning is a protective phenomenon, by which brief ischemic stimuli in a vascular bed are able to counteract the damage from a longer subsequent ischemia.
Elpidio Santillo +1 more
doaj +1 more source

