Results 81 to 90 of about 25,118 (249)

Low‐dose X‐ray radiation induces an adaptive response: A potential countermeasure to galactic cosmic radiation exposure

Experimental Physiology, EarlyView.
Abstract Space exploration involves many dangers including galactic cosmic radiation (GCR). This class of radiation includes high‐energy protons and heavy ionizing ions. NASA has defined GCR as a carcinogenic risk for long‐duration space missions. To date, no clear strategy has been developed to counter chronic GCR exposure.
Siena Edwards, Jessica Adams, Anastasia Tchernikov, John G. Edwards   +3 more
wiley   +1 more source

Evaluation of the effects of ischemic preconditioning on the hematological parameters of rats subjected to intestinal ischemia and reperfusion

Clinics, 2015
OBJECTIVES: Intestinal ischemia/reperfusion often leads to acute lung injury and multiple organ failure. Ischemic preconditioning is protective in nature and reduces tissue injuries in animal and human models.
Muhammad Tahir, Samina Arshid, Ana Maria C. Heimbecker, Mariana S. Castro, Edna Frasson de Souza Montero, Belchor Fontes, Wagner Fontes   +6 more
doaj   +1 more source

Blood flow restriction: The acute effects of body tilting and reduced gravity analogues on limb occlusion pressure

Experimental Physiology, EarlyView.
Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley   +1 more source

Clinical Application of Ischemic Preconditioning in the Elderly

Dose-Response, 2010
A mild stress such as brief ischemic episodes may protect the heart from a successive and more prolonged myocardial ischemia (ischemic preconditioning).
Pasquale Abete, Francesco Cacciatore, Gianluca Testa, David Della-Morte, Gianluigi Galizia, Nicola Ferrara, Franco Rengo   +6 more
doaj   +1 more source

The effect of remote ischemic preconditioning and aerobic exercise on myocardial BIP and eIF2α gene expression in male rats with myocardial infarction [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز
Background. Endoplasmic reticulum stress contributes to the development of cardiovascular diseases. In contrast, regular physical exercise has been considered a powerful tool to prevent and control cardiovascular diseases.
Atefeh Ghorbanipor, Amin Farzaneh Hesari, Parvin Farzanegi, Abdolreza Jafari   +3 more
doaj   +1 more source

Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection

, 2004
Background - Transient (low-conductance) opening of the mitochondrial permeability transition pore (mPTP) may limit mitochondrial calcium load and mediate mitochondrial reactive oxygen species (ROS) signaling.
Wynne, A, Duchen, M, Yellon, D, Hausenloy, D   +3 more
core  

Protection of coronary circulation by remote ischemic preconditioning: An intriguing research frontier

Cardiology Plus, 2018
Ischemic preconditioning is a protective phenomenon, by which brief ischemic stimuli in a vascular bed are able to counteract the damage from a longer subsequent ischemia.
Elpidio Santillo, Raffaele Antonelli-Incalzi   +1 more
doaj   +1 more source

Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide

, 2001
Background: The sulfonylurea glibenclamide (Glib) abolishes the cardioprotective effect of ischemic preconditioning (IP), presumably by inhibiting mitochondrial KATP channel opening in myocytes. Glimepiride (Glim) is a new sulfonylurea reported to affect
Baxter, G.F., Standen, N.B., Yellon, D.M., Lawrence, C.L., Maddock, H.L., Mocanu, M.M.   +5 more
core  

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Preconditioning of the response to ischemia/ reperfusion-induced plasma leakage in hamster cheek pouch microcirculation

Clinics, 2012
OBJECTIVE: Ischemic preconditioning and some drugs can protect tissues from injury by preserving microcirculation. This study evaluated vascular permeability in a hamster cheek pouch preparation using either short ischemic periods or bradykinin as ...
Fabiana Gomes da Conceição, Cristiane Maria Simonato Conde, Erik Svensjö, Daniel Alexandre Bottino, Eliete Bouskela   +4 more
doaj   +1 more source