Results 151 to 160 of about 50,595 (277)

Circular RNAs in Diabetic Foot Ulcers: A Scoping Review of Clinical, Preclinical, and In Silico Evidence on Diagnostic and Therapeutic Potentials

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
This figure summarises circRNAs identified as therapeutic or pathogenic targets in animal models of diabetic foot ulcers. Protective circRNAs delivered via exosomes, hypoxia‐preconditioned exosomes, or lipid nanoparticles promote angiogenesis, autophagy, and oxidative stress resistance. In contrast, silencing of pathogenic circRNAs such as circ_0005654
Amir Reza Ghafourian   +6 more
wiley   +1 more source

CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation [PDF]

open access: yes, 2003
CD40 is a 48-kDa phosphorylated transmembrane glycoprotein belonging to the TNF receptor superfamily. CD40 has been demonstrated on a range of cell types, and it has an important role in adaptive immunity and inflammation.
Callard, R.E.   +4 more
core  

Six Hundred and Sixty Nanometer Light Exposure‐Induced Alterations in Actin Filament, Mitochondrial Morphological Dynamics, and Migration in Mesenchymal Stem Cells

open access: yesJournal of Biophotonics, Volume 19, Issue 1, January 2026.
Six hundred and sixty nanometer light‐induced alteration of actin filament cytoskeleton, mitochondrial morphological dynamics, and enhanced migration in adipose‐derived mesenchymal stem cells. ABSTRACT Actin cytoskeleton alteration and cell homing/migration are crucial determinants for the success of stem cell (SC) based therapy.
Mahima Rastogi   +2 more
wiley   +1 more source

Microcirculatory effects of local and remote ischemic preconditioning in supraceliac aortic clamping

open access: green, 2010
Nilon Erling   +6 more
openalex   +2 more sources

Organ Transplantation: Current Status, Challenges, and Future Prospects

open access: yesMedComm, Volume 7, Issue 1, January 2026.
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley   +1 more source

eVLP‐Mediated Cas9 Delivery for Preventing IBMIR in Islet Transplantation

open access: yesSmall, Volume 22, Issue 1, 2 January 2026.
Engineered virus‐like particles (eVLPs) are used to deliver Cas9 nuclease to knock out tissue factor (TF) and plasminogen activator inhibitor‐1 (PAI‐1) genes in pancreatic islets. The edited islets maintained viability and function, while reducing instant blood‐mediated inflammatory reaction (IBMIR) markers and improving glycemic control in diabetic ...
Manju Shrestha   +6 more
wiley   +1 more source

Unveiling the Proteomic Landscape of Extracellular Vesicles: Implications for Neurodegeneration and Neuroprotection

open access: yesJournal of Neurochemistry, Volume 170, Issue 1, January 2026.
Extracellular vesicles (EVs) are tiny, membrane‐covered packets that cells naturally release to send molecular information to one another. In the brain, they function as couriers that move proteins, lipids, and other signals between neurons, glial cells, and the blood–brain barrier.
Berenice N. Bernal‐Vicente   +4 more
wiley   +1 more source

The role of orexin A in the pathogenesis of ischaemic stroke at high altitude

open access: yesExperimental Physiology, Volume 111, Issue 1, Page 257-269, 1 January 2026.
Schematic illustration of the experimental design. This study investigated the role of Orexin A in the pathogenesis of ischemic stroke at high altitude. Abstract Orexin offers protection against cerebral ischaemia–reperfusion injury, with high altitude playing a key role in modulating its expression.
Minxia Zhu   +7 more
wiley   +1 more source

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