Experimental Physiology, Volume 111, Issue 4, Page 2058-2072, 1 April 2026.Abstract Cardiosphere‐derived cells (CDCs) are a promising in vitro model for studying myocardial ischaemia–reperfusion (I–R) injury and testing potential therapeutic interventions. This study investigated the suitability of CDCs as a model for myocardial infarction (MI) and the effects of prolyl hydroxylase inhibitor (PHI) administration during ...
Luca Salhöfer +4 more
wiley +1 more source
Models of the human heart for biomedical research: Opportunities and challenges
Physiological Reports, Volume 14, Issue 7, April 2026.This manuscript reviews models that can be used to study the physiology and pathophysiology of the heart, and describes some the limitaions and ethical concerns associated with the use of human tissue. Abstract Model systems that mimic human cardiac structure and function are essential for the development of novel diagnostics and effective treatments ...
Katrin Streckfuss‐Bömeke +21 more
wiley +1 more source
Adding ROS Scavengers to Cold K\u3csup\u3e+\u3c/sup\u3e Cardioplegia Reduces Superoxide Emission During 2 h Global Cold Cardiac Ischemia [PDF]
, 2012 We reported that the combination of reactive oxygen species (ROS) quenchers Mn(III) tetrakis (4-benzoic acid) porphyrin (MnTBAP), catalase, and glutathione (MCG) given before 2 hours cold ischemia better protected cardiac mitochondria against cold ...
Aldakkak, Mohammed +4 more
core +1 more source
Physiological significance of autocrine orexinergic signaling in extra‐hypothalamic tissues
Physiological Reports, Volume 14, Issue 8, April 2026.Mechanisms of autocrine orexinergic effects in extra‐hypothalamic tissues. Abstract Orexin‐A and orexin‐B, originally discovered as hypothalamic neuropeptides, have been detected in extra‐hypothalamic tissues together with their receptors (OX1R and OX2R) since the early 2000s.
Jean Claude Hakizimana +2 more
wiley +1 more source
Peroxisome proliferator‐activated receptor gamma participates in the acquisition of brain ischemic tolerance induced by ischemic preconditioning via glial glutamate transporter 1 in vivo and in vitro [PDF]
, 2019 Congcong Zhao +12 more
openalex +1 more source
Targeting Arterial Dysfunction in Cardiovascular Disease Using Stem Cell‐Based Therapies
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.Graphical presentation of stem cell‐based therapies for arterial dysfunction, endothelial repair and regeneration strategies. SMC, smooth muscle cell. ABSTRACT Arterial regeneration represents a critical frontier in cardiovascular medicine, as progressive endothelial dysfunction, maladaptive vascular smooth muscle cell (SMC) plasticity, and chronic ...
Yun‐Yu Ma, Shu‐Yao Zhu, Yi Song
wiley +1 more source
Gender differences in effect of ischemic preconditioning in patients with congestive heart failure
, 2015 S G Khayrullina +2 more
openalex +2 more sources
Attenuated inflammatory profile following single and repeated handgrip exercise and remote ischemic preconditioning in patients with cerebral small vessel disease [PDF]
, 2022 Thijs Landman +5 more
openalex +1 more source
Кубанский научный медицинский вестник, 2015 The possibility of vardenafil using for pharmacological preconditioning in surgery is studied. Experiment was carried out on Wistar rats. The influence of vardenafil on the survival of pedicled isolated skin flap and the state of the microvasculature in ...
I. M. Kolesnik +2 more
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