Results 11 to 20 of about 42,902 (229)

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source

Mechanisms and Prospects of Ischemic Tolerance Induced by Cerebral Preconditioning [PDF]

International Neurourology Journal, 2010
In the brain, brief episodes of ischemia induce tolerance against a subsequent severe episode of ischemia. This phenomenon of endogenous neuroprotection is known as preconditioning-induced ischemic tolerance.
Mohammad Iqbal Hossain Bhuiyan, Youn Jung Kim   +1 more
doaj   +1 more source

Ischemic Preconditioning [PDF]

Stroke, 2004
The quest for effective therapeutics for the treatment of stroke has resulted in more than a dozen clinical trials of putative neuroprotective drugs. None has proven successful. Although trial design may be a factor in these failures, the negative results of these attempts to find effective exogenous therapies for cerebral ischemia have stimulated ...
Antoine Hakim, Roger Simon
openaire   +1 more source

Alleviation of ischemic brain injury by exercise preconditioning is associated with modulation of autophagy and mitochondrial dynamics in cerebral cortex of female aged mice

Experimental Gerontology, 2023
Evidence from clinical studies and preclinical studies supports that exercise preconditioning can not only reduce the risk of stroke but also improve brain tissue and functional outcome after stroke.
Yuan-Yuan Qin, Shan-Yao Pan, Jia-Ru Dai, Qing-Mei Wang, Xun Luo, Zheng-Hong Qin, Li Luo   +6 more
doaj   +1 more source

Exercise Preconditioning Ameliorates Cognitive Impairment in Mice with Ischemic Stroke by Alleviating Inflammation and Modulating Gut Microbiota

Mediators of Inflammation, 2022
Several studies have demonstrated that exercise preconditioning is an effective means of alleviating poststroke cognitive impairment (PSCI). Mechanisms of regulating cognitive function have not been fully elucidated. Herein, the present study is aimed at
Heng Lv, Shasha Wang, Meihui Tian, Liya Wang, Jie Gao, Qitao Zhao, Zhaoyu Li, Xianjie Jia, Ying Yu   +8 more
doaj   +1 more source

Effects of remote limb ischemic conditioning on muscle strength in healthy young adults: A randomized controlled trial [PDF]

, 2020
Remote limb ischemic conditioning (RLIC) is a clinically feasible method in which brief, sub-lethal bouts of ischemia protects remote organs or tissues from subsequent ischemic injury.
Bland, Marghuretta D, Chen, Ling, Gidday, Jeffrey M, Hershey, Tamara, Lang, Catherine E, Lee, Jin-Moo, Mattlage, Anna E, Surkar, Swati M   +7 more
core   +2 more sources

Unique Transcriptional Profile of Sustained Ligand-Activated Preconditioning in Pre- and Post-Ischemic Myocardium [PDF]

, 2013
BACKGROUND: Opioidergic SLP (sustained ligand-activated preconditioning) induced by 3–5 days of opioid receptor (OR) agonism induces persistent protection against ischemia-reperfusion (I-R) injury in young and aged hearts, and is mechanistically distinct
Ashton, Kevin J., Headrick, John P., Kiessling, Can J., Peart, Jason N., See Hoe, Louise E., Tupicoff, Amanda, Williams-Pritchard, Grant   +6 more
core   +9 more sources

The Effect of Ischemic Preconditioning on Repeated Sprint Cycling Performance [PDF]

, 2014
Purpose: Ischemic preconditioning enhances exercise performance. We tested the hypothesis that ischemic preconditioning would improve intermittent exercise in the form of a repeated sprint test during cycling ergometry.Methods: In a single-blind ...
Bezodis, Neil E., Glaister, Mark, Patterson, Stephen D., Pattison, John R.   +3 more
core   +3 more sources

Myocardial ischemic preconditioning in a porcine model leads to rapid changes in cardiac extracellular vesicle messenger RNA content

International Journal of Cardiology: Heart & Vasculature, 2015
Background: Extracellular vesicles (EVs) are thought to exert protective effects after ischemic and remote ischemic preconditioning. It is not well understood which EV content factors are most relevant for protective effects. We hypothesize that ischemic
Kristina Svennerholm, Pouria Rodsand, Urban Hellman, Marie Lundholm, Anders Waldenström, Björn Biber, Gunnar Ronquist, Michael Haney   +7 more
doaj   +1 more source

The method of distant preconditioning and results of its application in renal transplantation from the living family donor

Клінічна хірургія, 2021
Objective. Elaboration of method for the intraoperative ischemic-reperfusion trauma softening - distant ischemic preconditioning and investigation of results of its introduction into clinical practice. Materials and methods.
M. І. Kyrychenko, A. V. Bilyayev, N. G. Davydenko, A. O. Bychkova, O. V. Storozhuk   +4 more
doaj   +1 more source