Results 71 to 80 of about 332,373 (294)

In-Hospital Ischemic Stroke [PDF]

The Neurohospitalist, 2015
Between 2.2% and 17% of all strokes have symptom onset during hospitalization in a patient originally admitted for another diagnosis or procedure. These in-hospital strokes represent a unique population with different risk factors, more mimics, and substantially worsened outcomes compared to community-onset strokes.
openaire   +3 more sources

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

Advanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang, Yousheng Wu, Xuanlin Su, Kaiwei Cai, Man Ke, Niu He, Huili Zhu, Zefeng Tan, Jielin Zhu, Wensheng He, Min Peng, Shiqing Zhang, Hongcheng Mai, Anding Xu, Dan Lu   +14 more
wiley   +1 more source

Approach to Ischemic Stroke

McGill Journal of Medicine, 2021
An approach to managing acute ischemic stroke includes recognition, investigations, treatment, and secondary prevention.  Firstly, facial drooping, limb weakness and slurred speech are some common signs that should raise the suspicion for stroke.  Upon presentation, investigations, including the national institute of health stroke scale and a CT head ...
openaire   +4 more sources

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

The role of insulin receptor substrate 1 gene polymorphism Gly972Arg as a risk factor for ischemic stroke among Indonesian subjects

BMC Research Notes, 2018
Objective The identification of new genetic-associated risk factor of ischemic stroke could improves strategies for stroke prevention. This study aims to identify insulin receptor substrate 1 (IRS-1) gene polymorphism Gly972Arg as the risk factor for ...
Syahrul, Samekto Wibowo, Sofia Mubarika Haryana, Indwiani Astuti, Fariz Nurwidya   +4 more
doaj   +1 more source

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidian Chen   +21 more
wiley   +1 more source

Prevention of Ischemic Stroke. [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2000
Prevention of Ischemic Stroke. Edited by cesare fieschiand mare fisher (Pp 304, £65.00). Published by Martin Dunitz Publishers, London, 1999. ISBN 1-85317-738-5. This is a multiauthor reference book with contributions from epidemiologists, neuroradiologists, neurologists, and cardiologists.
openaire   +3 more sources

Network Desynchronization with Sine Waves: from Synchrony to Asynchrony by Periodic Stimulation

Advanced Science, EarlyView.
Exogenous alternating current fields are explored and interact with cerebral cortex slow waves in vitro and in silico. Varying frequency and amplitude of sine waves result in distinct network dynamics, from phase‐locking and entrainment to desynchronization. These responses occupy specific regions within the parameter space.
Joana Covelo, Martina Cortada, Gianni V. Vinci, Maurizio Mattia, Maria V. Sanchez‐Vives   +4 more
wiley   +1 more source

A study on structural imaging changes and serum neurofilament light chain (NfL) levels in individuals with white matter hyperintensities, combining imaging techniques with biomarker analysis

IBRO Neuroscience Reports
Objective: To elucidate the association between serum neurofilament light chain (NfL) levels and structural brain alterations in individuals exhibiting white matter hyperintensities (WMHs), as well as to investigate the potential utility of serum NfL as ...
Meini Wu, Zihao Li, Yuhang Ren, Siou Li, Weina Zhao, Jian Xing, Jiangnan Yi, Fengze Zhao, Changhao Yin   +8 more
doaj  

Association between genetic variant on chromosome 12p13 and stroke survival and recurrence: a one year prospective study in Taiwan

Journal of Biomedical Science, 2012
Background The association between ischemic stroke and 2 single nucleotide polymorphisms (SNPs) on chromosome 12p13, rs12425791 and rs11833579 appears inconsistent across different samples.
Hsieh Yi-Chen, Seshadri Sudha, Chung Wen-Ting, Hsieh Fang-I, Hsu Yi-Hsiang, Lin Huey-Juan, Tseng Hung-Pin, Lien Li-Ming, Bai Chyi-Huey, Hu Chaur-Jong, Jeng Jiann-Shing, Tang Sung-Chun, Chen Chin-I, Yu Chia-Chen, Chiou Hung-Yi   +14 more
doaj   +1 more source