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Integrated microoptical system for continuous fluorescence monitoring of microtissues. [PDF]
Microsyst NanoengTian X +10 more
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A New Era in Islet Transplantation: Stem Cell-Derived and Gene-Edited Islet Therapies. [PDF]
Diabetes Metab JLee J, Lee SH.
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Journal of Hepato-Biliary-Pancreatic Surgery, 2000
Recently, significant advances have been made in the number and purity of islets that can be retrieved from the human pancreas, thus enabling several centers to initiate or resume clinical trials of islet transplantation in type I diabetic patients. Although the success rate of islet transplantation is lower than that of pancreas transplantation in ...
K, Inoue, M, Miyamoto
openaire +2 more sources
Recently, significant advances have been made in the number and purity of islets that can be retrieved from the human pancreas, thus enabling several centers to initiate or resume clinical trials of islet transplantation in type I diabetic patients. Although the success rate of islet transplantation is lower than that of pancreas transplantation in ...
K, Inoue, M, Miyamoto
openaire +2 more sources
Journal of Materials Chemistry B, 2018
Review of emerging advances and persisting challenges in the engineering and translation of islet encapsulation technologies.
Alexander Ulrich Ernst +2 more
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Review of emerging advances and persisting challenges in the engineering and translation of islet encapsulation technologies.
Alexander Ulrich Ernst +2 more
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Current Diabetes Reports, 2016
Islet autoantibodies are the main markers of pancreatic autoimmunity in type 1 diabetes (T1D). Islet autoantibodies recognize insulin (IAA), glutamic acid decarboxylase (GADA), protein phosphatase-like IA-2 (IA-2A), and ZnT8 (ZnT8A), all antigens that are found on secretory granules within pancreatic beta cells.
Vito, Lampasona, Daniela, Liberati
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Islet autoantibodies are the main markers of pancreatic autoimmunity in type 1 diabetes (T1D). Islet autoantibodies recognize insulin (IAA), glutamic acid decarboxylase (GADA), protein phosphatase-like IA-2 (IA-2A), and ZnT8 (ZnT8A), all antigens that are found on secretory granules within pancreatic beta cells.
Vito, Lampasona, Daniela, Liberati
openaire +2 more sources
Pig islets for clinical islet xenotransplantation
Current Opinion in Nephrology and Hypertension, 2009Allogeneic islet transplantation faces difficulties because organ shortage is recurrent; several pancreas donors are often needed to treat one diabetic recipient; and the intrahepatic site of islet implantation may not be the most appropriate one. Another source of insulin-producing cells, therefore, would be of major interest, and pigs represent a ...
Denis, Dufrane, Pierre, Gianello
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Current Molecular Medicine, 2006
Islet cell transplantation is an attractive alternative therapy to conventional insulin treatment or vascularized whole pancreas transplantation for type 1 diabetic patients. It represents a successful example of somatic cell therapy in humans based on complex procedures for islet isolation from whole pancreas. The islets, that are only 1% of the total
Bertuzzi F +2 more
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Islet cell transplantation is an attractive alternative therapy to conventional insulin treatment or vascularized whole pancreas transplantation for type 1 diabetic patients. It represents a successful example of somatic cell therapy in humans based on complex procedures for islet isolation from whole pancreas. The islets, that are only 1% of the total
Bertuzzi F +2 more
openaire +3 more sources