Results 241 to 250 of about 192,930 (304)

TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network. [PDF]

Nat Commun
Walth-Hummel AA, Jouffe C, Weber P, Motzler K, Geppert J, Sterr M, Gan W, Szczerbinska I, König AC, Hauck SM, Terron-Exposito R, Hass D, Wang C, Dyar KA, Lyon JG, Lickert H, Ämmälä C, Herzig S, Ashcroft FM, Bakhti M, MacDonald PE, Rohm M.   +21 more
europepmc   +1 more source

Amylin analogues as a novel perspective in anti‐obesity therapy

British Journal of Pharmacology, EarlyView.
Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley   +1 more source

Addition of human platelet lysate to islet culture medium suppresses islet loss and improves transplantation outcomes. [PDF]

Cell Transplant
Noguchi H, Miyagi-Shiohira C, Sadahira T, Watanabe M, Saitoh I.   +4 more
europepmc   +1 more source

An experimental approach to assess the combined effects of multiple stressors on a large vertebrate species

Conservation Biology, EarlyView.
Abstract The design of experiments to investigate the combined effects of multiple stressors requires exposing target organisms to multiple combinations of stressor doses. Concurrent manipulation of stressors is often infeasible with wildlife, but long‐lasting health effects allow individual health to be used as an integrator of prior stressor exposure.
Enrico Pirotta, Catriona M. Harris, Lori H. Schwacke, Len Thomas, Jason B. Allen, Aaron A. Barleycorn, Marco Casoli, Jonathan Crossman, Laura Aichinger Dias, Laura Engleby, Erin LaBrecque, Jenny A. Litz, Katherine A. McHugh, Patrick J. O. Miller, Michael J. Moore, Theoni Photopoulou, Brian M. Quigley, Cynthia R. Smith, Brandon L. Southall, Todd R. Speakman, Ryan Takeshita, Christina N. Toms, Randall S. Wells, Eric S. Zolman, Peter L. Tyack   +24 more
wiley   +1 more source

Molecular mechanisms responsible for mesenchymal stem cell-dependent improvement of islet cell transplantation. [PDF]

Cell Transplant
Volarevic V, Randall Harrell C, Fellabaum C, Djonov V, Volarevic A.   +4 more
europepmc   +1 more source

Improving the use of expert opinion in disease risk analysis for conservation translocations

Conservation Biology, EarlyView.
Abstract Conservation translocations are subject to considerable uncertainty and risk, of which disease is one of the most recognized. To address disease risks, several protocols for qualitative disease risk analysis (qDRA) exist and are used for responsible conservation translocation planning.
John G. Ewen, Stefano Canessa, Caitlin E. Andrews, Katie M. Beckmann, Irene Bueno, Deidre K. Fontenot, Caio Kenup, Suzanne Medina, Axel Moehrenschlager, Francesco Origgi, Bruce Rideout, Anthony W. Sainsbury, Thierry M. Work, Claudia Carraro   +13 more
wiley   +1 more source

Magnetic Bead-Guided Assembly of 3D Primary Human Islet Cells in Decellularized Pancreatic Scaffolds. [PDF]

Cells
Mantovani MDC, Carreira ACO, Damaceno-Rodrigues NR, Caldini EG, Sogayar MC.   +4 more
europepmc   +1 more source

Low Responsiveness of Macroencapsulated Human Islets Towards Glucose Challenge Despite Excellent Survival in Silicone-Based Oxygen-Delivering Devices. [PDF]

Bioengineering (Basel)
Brandhorst D, Brandhorst H, Domingo-Lopez DA, O'Cearbhaill E, Coulter FB, Spiers R, Deotti S, Kelly HM, Duffy GP, Johnson PRV.   +9 more
europepmc   +1 more source

Use of Small Organic Molecules to Improve Pancreatic Beta Cell Resilience to IAPP-Induced Proteotoxic Stress. [PDF]

Int J Mol Sci
Valshon K, Kondrot K, Uehara H, Alexander M, Ichii H.   +4 more
europepmc   +1 more source

Human islet isolation optimization: Insights from donor and isolation procedural factors. [PDF]

Cell Transplant
Yang Q, Xi Y, Yang Z, Deng H, Wang Z, Li G, Augusta K, Shah S, Markmann JF, Lei J.   +9 more
europepmc   +1 more source