Results 11 to 20 of about 424,952 (202)
Cell Transplantation, 2019 Beta cell replacement is an exciting field where new beta cell sources and alternative sites are widely explored. The liver has been the implantation site of choice in the clinic since the advent of islet transplantation. However, in most cases, repeated
Hanna Liljebäck +3 more
doaj +2 more sources
Superiority of Small Islets in Human Islet Transplantation [PDF]
Diabetes, 2007 Many factors influence the outcome of islet transplantation. As islets in the early posttransplant setting are supplied with oxygen by diffusion only and are in a hypoxic state in the portal system, we tested whether small human islets are superior to large islets both in vitro and in vivo.
Lehmann, R +8 more
openaire +6 more sources
Lesió i protecció de les cèl·lules beta en el trasplantament d'illots pancreàtics [PDF]
, 2007 [cat] El trasplantament d'illots pancreàtics pot ser una bona teràpia per els malalts amb diabetis mellitus de tipus 1, però hi ha alguns problemes que cal solventar abans que sigui un tractament estès.
Montolio Rusiñol, Marta
core +6 more sources
Immune modulation with amniotic epithelial cells in pancreatic islet transplantation [PDF]
, 2012 Chronic systemic immunosuppression in pancreatic islet transplantation restricts its clinical application. This study aims to explore the potential of cell-mediated immune-modulation as an alternative to conventional immunosuppressive regimens ...
Qureshi, Khalid
core +7 more sources
, 2022 OBJECTIVE To determine long-term outcomes for islet-alone and islet-after-kidney transplantation in adults with type 1 diabetes complicated by impaired awareness of hypoglycemia.
Hunsicker, Lawrence G +20 more
core +2 more sources
Anti-Oxidative Therapy in Islet Cell Transplantation
Antioxidants, 2022 Islet cell transplantation has become a favorable therapeutic approach in the treatment of Type 1 Diabetes due to the lower surgical risks and potential complications compared to conventional pancreas transplantation.
Natsuki Eguchi +5 more
doaj +1 more source
Subcutaneous device-free islet transplantation
Frontiers in Immunology, 2023 Diabetes mellitus is a chronic metabolic disease, characterized by high blood sugar levels; it affects more than 500 million individuals worldwide. Type 1 diabetes mellitus (T1DM) is results from insufficient insulin secretion by islets; its treatment ...
Xudong Zhou +8 more
doaj +1 more source
Inflammatory response and its impact on outcome of islet transplantation [PDF]
CellR4, 2019 Inflammation plays a detrimental role in islet transplantation leading to poor clinical outcomes. One of the major contributors of islet loss is IBMIR leading to 50% decrease in transplanted islet mass immediately post-transplantation.
M. Kanak, P. Saravanan, M. Levy
doaj +1 more source
Immunosuppression in islet transplantation [PDF]
Journal of Clinical Investigation, 2008 Islet transplantation can temporarily cure type 1 diabetes mellitus (T1DM) but requires simultaneous immunosuppression to avoid allograft rejection. In this issue of the JCI, Monti et al. report that immune conditioning via use of the Edmonton protocol - a treatment approach in which T1DM patients infused with pancreatic islets from multiple cadaveric ...
Tom, Van Belle, Matthias, von Herrath
openaire +2 more sources
Update on Islet Transplantation [PDF]
Cold Spring Harbor Perspectives in Medicine, 2012 Clinical islet transplantation has progressed considerably over the past 12 years, and >750 patients with type 1 diabetes have received islet transplants internationally over this time. Many countries are beginning to accept the transition from research to accepted and funded clinical care, especially for patients with brittle control that cannot be ...
Michael, McCall, A M James, Shapiro
openaire +2 more sources