Results 91 to 100 of about 12,558 (256)

Membrane Protein Profiling of Human Islets of Langerhans Using Several Extraction Methods [PDF]

, 2010
Introduction Proteomic characterization of the human pancreatic islets, containing the insulin producing beta-cells, is likely to be of great importance for improved treatment and understanding of the pathophysiology of diabetes mellitus.
Hans Tornqvist, Jan W. Eriksson, Lars Johansson, Olle Korsgren, Pia Davidsson, Sara F. Hansson, Åsa Henriksson   +6 more
core   +1 more source

Xenotransplantation of Embryonic Pig Kidney or Pancreas to Replace the Function of Mature Organs

Journal of Transplantation, 2011
Lack of donor availability limits the number of human donor organs. The need for host immunosuppression complicates transplantation procedures. Ultrastructurally precise kidneys differentiate in situ following xenotransplantation in mesentery of ...
Marc R. Hammerman
doaj   +1 more source

Clinical Trial Protocol for Porcine Islet Xenotransplantation in South Korea [PDF]

Diabetes & Metabolism Journal
Background Islet transplantation holds promise for treating selected type 1 diabetes mellitus patients, yet the scarcity of human donor organs impedes widespread adoption.
Byung-Joon Kim, Jun-Seop Shin, Byoung-Hoon Min, Jong-Min Kim, Chung-Gyu Park, Hee-Jung Kang, Eung Soo Hwang, Won-Woo Lee, Jung-Sik Kim, Hyun Je Kim, Iov Kwon, Jae Sung Kim, Geun Soo Kim, Joonho Moon, Du Yeon Shin, Bumrae Cho, Heung-Mo Yang, Sung Joo Kim, Kwang-Won Kim   +18 more
doaj   +1 more source

Sertoli cells as biochambers [PDF]

, 2004
According to the present invention, there is provided a biological chamber system having a biochamber defined by outer walls of Sertoli cells. Also provided is a transplantation facilitator including a biochamber.
Cameron, Don F., Hushen, Joelle J., Sanberg, Paul R., Saporta, Samuel   +3 more
core   +2 more sources

FEM-based oxygen consumption and cell viability models for avascular pancreatic islets [PDF]

, 2009
The function and viability of cultured, transplanted, or encapsulated pancreatic islets is often limited by hypoxia because these islets have lost their vasculature during the isolation process and have to rely on gradient-driven passive diffusion, which
Peter Buchwald, C Ricordi, P Fiorina, SA Nanji, AM Shapiro, PM Galletti, CK Colton, TB Murdoch, T Kin, C Ricordi, S Morini, I Konstantinova, O Cabrera, J Suckale, N Lifson, B Vasir, L Jansson, AS Narang, S Sander, H Ichii, KK Papas, RJ Fleischaker Jr, CA Fraker, ES Avgoustiniatos, WL Robb, V Singh, M Mikola, ES Avgoustiniatos, Y Martin, HK Tilakaratne, JL Dulong, JD Gross, KK Papas, M Radisic, TW Secomb, NM Tsoukias, OC Zienkiewicz, Comsol, AB, KF Riley, DF Wilson, RJ Silbey, JL Dulong, KK Papas, E Avgoustiniatos, IR Sweet, IR Sweet, Comsol, AB, W Hayduk, DM Jenkins, N Bocca, Comsol, AB, JC Hutton, EA Longo, IR Sweet, W Wang, A Despopoulos, T Kaihoh, J Jo, S Merani, RR MacGregor, AE Greijer, AR Hogan, KE Dionne, N Bocca, O Cabrera, FC Schuit   +65 more
core   +1 more source

Comparative efficacy of Belzer or Euro-Collins solutions for pancreatic preservation during cold ischemic storage in rats [PDF]

, 2014
PURPOSE:To compare the efficacy of different types of solutions (Belzer or Euro-Collins) for the preservation of rat pancreas during cold ischemia. METHODS:Thirty Wistar rats were divided into three groups according to the perfusion or storage solution ...
Goldenberg, Alberto, Gonzalez, Adriano Miziara, Netto, Alcides Augusto Salzedas, Perez, Rogerio Renato   +3 more
core   +3 more sources

Obstacles on the way to the clinical visualisation of beta cells: looking for the Aeneas of molecular imaging to navigate between Scylla and Charybdis [PDF]

, 2012
For more than a decade, researchers have been trying to develop non-invasive imaging techniques for the in vivo measurement of viable pancreatic beta cells.
K. Andralojc, M. Srinivas, M. Brom, L. Joosten, I. J. M. de Vries, D. L. Eizirik, O. C. Boerman, P. Meda, M. Gotthardt   +8 more
core   +1 more source

Isolation, banking, encapsulation and transplantation of different types of Langerhans islets

Polish Archives of Internal Medicine, 2009
The discovery of a cure for diabetes is a dream of many medical researchers. The transplantation of Langerhans islets is a potential treatment of choice for patients with type 1 diabetes as a source of endogenous insulin for the recipient.The aim of the experiment was to transplant Langerhans islets without immunosuppression.
Magdalena, Antosiak-Iwańska, Elzbieta, Sitarek, Marek, Sabat, Ewa, Godlewska, Joanna, Kinasiewicz, Andrzej, Weryński   +5 more
openaire   +2 more sources

The pancreas anatomy conditions the origin and properties of resident macrophages [PDF]

, 2015
We examine the features, origin, turnover, and gene expression of pancreatic macrophages under steady state. The data distinguish macrophages within distinct intrapancreatic microenvironments and suggest how macrophage phenotype is imprinted by the local
Ajami, Bain, Banaei-Bouchareb, Boris Calderon, Boyer, Boyer, Buza-Vidas, Böiers, Calderon, Calderon, Carrero, Chu, Clark, Cucak, DeFalco, Dorothy K. Sojka, Ehses, Emil R. Unanue, Epelman, Epelman, Ferrante, Ferris, Gautier, Geutskens, Ginhoux, Gordon, Gosselin, Guilliams, Gwendalyn J. Randolph, Haniffa, Hashimoto, Hoeffel, Hume, Ino, Javier A. Carrero, Kenneth M. Murphy, Kumaravelu, Lavin, Lewis, Li, Lichanska, Lichanska, Lin, Lindsay Moore, Lumeng, Melli, Merad, Meredith, Mohan, Molawi, Murray, Murray, Peng, Pinto, Pollard, Richardson, Salvalaggio, Satpathy, Satpathy, Schulz, Serbina, Shaul, Sica, Slava Epelman, Sojka, Spits, Stephen T. Ferris, Wang, Wayne M. Yokoyama, Westwell-Roper, Xiao, Yin, Yona   +72 more
core   +2 more sources

Long‐term efficacy of encapsulated xenogeneic islet transplantation: Impact of encapsulation techniques and donor genetic traits

Journal of Diabetes Investigation
Aims/Introduction To investigate the long‐term efficacy of various encapsulated xenogeneic islet transplantation, and to explore the impact of different donor porcine genetic traits on islet transplantation outcomes.
Heon‐Seok Park, Eun Young Lee, Young‐Hye You, Marie Rhee, Jong‐Min Kim, Seong‐Soo Hwang, Poong‐Yeon Lee   +6 more
doaj   +1 more source